Reactive Oxygen Species
Research News and Information

Saturday, November 21, 2009

Oxidized low density lipoprotein decreases Rankl-induced differentiation of osteoclasts by inhibition of Rankl signaling.

29 Nov 2009 The role of OxLDL in the generation and progression of atherosclerosis is well admitted. In addition, it is well known that atherosclerosis is often accompanied by perturbations in bone remodeling, resulting in osteoporosis. In the current studies, ... Read more...

Membrane-dependent bystander effect contributes to amplification of the response to alpha-particle irradiation in targeted and nontargeted cells.

13 Nov 2009 PURPOSE: Free radicals are believed to play an active role in the bystander response. This study investigated their origin as well as their temporal and spatial impacts in the bystander effect. METHODS AND MATERIALS: We employed a precise ... Read more...

Clinical implication of urinary neutrophil gelatinase-associated lipocalin and kidney injury molecule-1 in patients with acute paraquat intoxication.

30 Oct 2009 BACKGROUND: Paraquat (PQ)-induced acute kidney injury (AKI) might show the role for reactive oxygen species (ROS) in AKI. The purpose of this study was to investigate the characteristics of early urinary biomarkers in patients with acute PQ ... Read more...

Latest indexed articles for 'Reactive Oxygen Species'

These are the very latest articles for this heading:

• Oxidized low density lipoprotein decreases Rankl-induced differentiation of osteoclasts by inhibition of Rankl signaling. 29 Nov 2009
• Membrane-dependent bystander effect contributes to amplification of the response to alpha-particle irradiation in targeted and nontargeted cells. 13 Nov 2009
• Clinical implication of urinary neutrophil gelatinase-associated lipocalin and kidney injury molecule-1 in patients with acute paraquat intoxication. 30 Oct 2009
• Hypoxia induces chemoresistance in ovarian cancer cells by activation of signal transducer and activator of transcription 3. 30 Oct 2009
• Heat-shock pretreatment inhibits sorbitol-induced apoptosis in K562, U937 and HeLa cells. 30 Oct 2009
• Elevated levels of select gangliosides in T cells from renal cell carcinoma patients is associated with T cell dysfunction. 13 Oct 2009
• The podocyte in diabetic kidney disease. 12 Oct 2009
• Beta-catenin is involved in alterations in mitochondrial activity in non-transformed intestinal epithelial and colon cancer cells. 11 Oct 2009
• Genetic silencing of Nox2 and Nox4 reveals differential roles of these NADPH oxidase homologues in the vasopressor and dipsogenic effects of brain angiotensin II. 3 Oct 2009
• Small-molecule screening using a human primary cell model of HIV latency identifies compounds that reverse latency without cellular activation. 29 Sep 2009
• Comment on "The bacterial fermentation product butyrate influences epithelial signaling via reactive oxygen species-mediated changes in cullin-1 neddylation". 29 Sep 2009
• Effect of the free radical scavenger edaravone on peripheral nerve ischemia-reperfusion injury. 29 Sep 2009
• The Arabidopsis ATAF1, a NAC transcription factor, is a negative regulator of defense responses against necrotrophic fungal and bacterial pathogens. 29 Sep 2009
• Photodynamic treatment of culture medium containing serum induces long-lasting toxicity in vitro. 29 Sep 2009
• Oxidative DNA modifications in hypoxic signaling. 29 Sep 2009
• Regulation of oxygen sensitivity in adrenal chromaffin cells. 29 Sep 2009
• Mitochondrial metabolism and cancer. 29 Sep 2009
• Cigarette smoke and reactive oxygen species metabolism: implications for the pathophysiology of Reinke's edema. 29 Sep 2009
• Ectopic expression of MgSM1, a Cerato-platanin family protein from Magnaporthe grisea, confers broad-spectrum disease resistance in Arabidopsis. 29 Sep 2009
• S100A8 and S100A9 are novel nuclear factor kappa B target genes during malignant progression of murine and human liver carcinogenesis. 29 Sep 2009

See a longer list of these articles.

Technical information about 'Reactive Oxygen Species'

Definition: Molecules or ions formed by the incomplete one-electron reduction of oxygen. These reactive oxygen intermediates include SINGLET OXYGEN; SUPEROXIDES; PEROXIDES; HYDROXYL RADICAL; and HYPOCHLOROUS ACID. They contribute to the microbicidal activity of PHAGOCYTES, regulation of signal transduction and gene expression, and the oxidative damage to NUCLEIC ACIDS; PROTEINS; and LIPIDS.

Registry Number: 0

Descriptor UI: D017382

Alternative terms: Reactive Oxygen Species; Oxygen Species, Reactive; Active Oxygen; Oxygen, Active; Oxygen Radicals; Pro-Oxidants; Pro Oxidants;

Related Mesh Headings: Free Radicals; Oxidative Stress;

Allowable Qualifiers: administration & dosage; adverse effects; analysis; antagonists & inhibitors; blood; cerebrospinal fluid; chemical synthesis; classification; diagnostic use; economics; history; immunology; isolation & purification; metabolism; pharmacokinetics; pharmacology; poisoning; radiation effects; standards; supply & distribution; therapeutic use; toxicity; urine; chemistry; contraindications; agonists;

Tree Number: D01.339.431; D01.650.775;

History Note: 1993