Receptor, Platelet-Derived Growth Factor beta - Genetics
Research News and Information

Monday, November 23, 2009

Additive effects of hyperbaric oxygen and platelet-derived growth factor-BB in chondrocyte transplantation via up-regulation expression of platelet-derived growth factor-beta receptor.

30 Oct 2009 The present study investigated the effects of hyperbaric oxygen (HBO) and platelet-derived growth factor-BB (PDGF-BB) in chondrocyte transplantation. In vitro, chondrocytes were treated with HBO, PDGF-BB, and HBO combined with PDGF-BB (H+P). Cell ... Read more...

(-)-Epigallocatechin gallate prevents carbon tetrachloride-induced rat hepatic fibrosis by inhibiting the expression of the PDGFRbeta and IGF-1R.

28 Jul 2009 Hepatic fibrosis is a major complication of various chronic liver diseases. Activated hepatic stellate cells (HSCs) play a critical role in the development of liver fibrosis and the axis of platelet-derived growth factor (PDGF)/PDGF receptor ... Read more...

Hypoxic ventilatory response in platelet-derived growth factor receptor-beta-knockout mice.

17 Jun 2009 The present study investigated whether the platelet-derived growth factor receptor (PDGFR)-beta-mediated mechanisms are involved in the hypoxic ventilatory response through modulating the N-methyl-D-aspartate (NMDA) function. The ventilatory changes ... Read more...

Latest indexed articles for 'Receptor, Platelet-Derived Growth Factor beta - Genetics'

These are the very latest articles for this heading:

• Additive effects of hyperbaric oxygen and platelet-derived growth factor-BB in chondrocyte transplantation via up-regulation expression of platelet-derived growth factor-beta receptor. 30 Oct 2009
• Trisomy 8 in PDGFRB-negative cells in a patient with imatinib-sensitive chronic myelomonocytic leukemia and t(5;16)(q33;p13), PDGFRB-NDE1 fusion. 29 Sep 2009
• (-)-Epigallocatechin gallate prevents carbon tetrachloride-induced rat hepatic fibrosis by inhibiting the expression of the PDGFRbeta and IGF-1R. 28 Jul 2009
• Hypoxic ventilatory response in platelet-derived growth factor receptor-beta-knockout mice. 17 Jun 2009
• Krüppel-like factor 4 inhibits proliferation by platelet-derived growth factor receptor beta-mediated, not by retinoic acid receptor alpha-mediated, phosphatidylinositol 3-kinase and ERK signaling in vascular smooth muscle cells. 14 Jun 2009
• Cell migration is regulated by platelet-derived growth factor receptor endocytosis. 13 Jun 2009
• ROS and PDGF-beta [corrected] receptors are critically involved in indoxyl sulfate actions that promote vascular smooth muscle cell proliferation and migration. Jun 2009
• Peripheral mural cell recruitment requires cell-autonomous heparan sulfate. 25 Apr 2009
• Design of chimeric histone deacetylase- and tyrosine kinase-inhibitors: a series of imatinib hybrides as potent inhibitors of wild-type and mutant BCR-ABL, PDGF-Rbeta, and histone deacetylases. 21 Apr 2009
• Regulation of platelet-derived growth factor receptor function by integrin-associated cell surface transglutaminase. 20 Apr 2009
• CSF1R copy number changes, point mutations, and RNA and protein overexpression in renal cell carcinomas. 15 Apr 2009
• Target-driven exploratory study of imatinib mesylate in children with solid malignancies by the Innovative Therapies for Children with Cancer (ITCC) European Consortium. 7 Apr 2009
• In vivo modulation of angiogenic gene expression by acyclic nucleoside phosphonates PMEDAP and PMEG. 30 Mar 2009
• Lack of evidence of stimulatory autoantibodies to platelet-derived growth factor receptor in patients with systemic sclerosis. 30 Mar 2009
• Combined anti-PDGFRalpha and PDGFRbeta targeting in non-small cell lung cancer. 30 Mar 2009
• Expression and molecular analysis of c-kit and PDGFRs in Kaposi's sarcoma of different stages and epidemiological settings. 17 Mar 2009
• [Myeloproliferative neoplasms and related diseases] 27 Feb 2009
• [Review of changes introduced by the new WHO classification (4th edition) of myeloid neoplasms. An overview] 27 Feb 2009
• [Hematological disorders and hypereosinophilias] 5 Feb 2009
• Identification of a MYO18A-PDGFRB fusion gene in an eosinophilia-associated atypical myeloproliferative neoplasm with a t(5;17)(q33-34;q11.2). 30 Jan 2009

See a longer list of these articles.

Technical information about 'Receptor, Platelet-Derived Growth Factor beta'

Definition: A PDGF receptor that binds specifically to the PDGF-B chain. It contains a protein-tyrosine kinase activity that is involved in SIGNAL TRANSDUCTION.

Registry Number: EC 2.7.1.112

Descriptor UI: D020797

Alternative terms: Receptor, Platelet-Derived Growth Factor beta; Receptor, Platelet Derived Growth Factor beta; PDGF beta Receptor; Platelet-Derived Growth Factor beta Receptor; Platelet Derived Growth Factor beta Receptor; CD140b Antigen; Antigen, CD140b; CD140b Antigens; PDGFR1; PDGFR beta; beta, PDGFR; Receptor, PDGF beta; PDGFRB; Antigens, CD140b;

Allowable Qualifiers: administration & dosage; analysis; antagonists & inhibitors; biosynthesis; blood; classification; deficiency; drug effects; genetics; history; immunology; isolation & purification; metabolism; physiology; radiation effects; therapeutic use; ultrastructure; chemistry; agonists;

Tree Number: D08.811.913.696.620.682.725.400.900.750; D12.776.543.750.060.625.400; D12.776.543.750.750.400.630.400;

History Note: 2000; use RECEPTOR, PDGF BETA (NM) 1994-1999

Technical Notes: DF: PDGF BETA RECEPT