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Receptor Protein-Tyrosine Kinases - Chemistry
Research News and Information
Definition of 'Receptor Protein-Tyrosine Kinases'A class of cellular receptors that have an intrinsic PROTEIN-TYROSINE KINASE activity. Common names: Receptor Protein-Tyrosine Kinases; Kinases, Receptor Protein-Tyrosine; Protein-Tyrosine Kinases, Receptor; Receptor Protein Tyrosine Kinases; PTK Receptors; Receptors, PTK; Receptor Protein-Tyrosine Kinase; Kinase, Receptor Protein-Tyrosine; Protein-Tyrosine Kinase, Receptor |
Monday, November 23, 2009
Crystal structure of the frizzled-like cysteine-rich domain of the receptor tyrosine kinase MuSK.
2 Aug 2009 
Muscle-specific kinase (MuSK) is an essential receptor tyrosine kinase for the establishment and maintenance of the neuromuscular junction (NMJ). Activation of MuSK by agrin, a neuronally derived heparan-sulfate proteoglycan, and LRP4 (low-density ... Read more...
Structural recognition of an optimized substrate for the ephrin family of receptor tyrosine kinases.
30 Jul 2009 Ephrin receptor tyrosine kinase A3 (EphA3, EC 2.7.10.1) is a member of a unique branch of the kinome in which downstream signaling occurs in both ligand- and receptor-expressing cells. Consequently, the ephrins and ephrin receptor tyrosine kinases ... Read more...
A glycopeptide regulating stem cell fate in Arabidopsis thaliana.
5 Jun 2009 The secreted peptide gene CLAVATA3 (CLV3) regulates stem cell fate in the shoot apical meristem in Arabidopsis thaliana plants, but the molecular structure of the active mature CLV3 peptide is controversial. Here, using nano-LC-MS/MS analysis of ... Read more...
Latest indexed articles for 'Receptor Protein-Tyrosine Kinases - Chemistry'
These are the very latest articles for this heading:
- Crystal structure of the frizzled-like cysteine-rich domain of the receptor tyrosine kinase MuSK. 2 Aug 2009
- Structural recognition of an optimized substrate for the ephrin family of receptor tyrosine kinases. 30 Jul 2009
- A glycopeptide regulating stem cell fate in Arabidopsis thaliana. 5 Jun 2009
- A new family of receptor tyrosine kinases with a venus flytrap binding domain in insects and other invertebrates activated by aminoacids.
19 May 2009 - Positive selection has driven the evolution of the Drosophila insulin-like receptor (InR) at different timescales. 25 Apr 2009
- Two GxxxG-like motifs facilitate promiscuous interactions of the human ErbB transmembrane domains. 6 Apr 2009
- Transmembrane helix of novel oncogene with kinase-domain (NOK) influences its oligomerization and limits the activation of RAS/MAPK signaling. 3 Feb 2009
- Development of multitargeted inhibitors of both the insulin-like growth factor receptor (IGF-IR) and members of the epidermal growth factor family of receptor tyrosine kinases. 28 Jan 2009
- PTK7 recruits dsh to regulate neural crest migration. 10 Nov 2008
- Structural insights into the inhibited states of the Mer receptor tyrosine kinase. 3 Nov 2008
- Cleavage of the Wnt receptor Ryk regulates neuronal differentiation during cortical neurogenesis. 30 Oct 2008
- Axl and Tyro3 modulate female reproduction by influencing gonadotropin-releasing hormone neuron survival and migration. 9 Sep 2008
- Template-directed self-assembly enhances RTK catalytic domain function. 30 Aug 2008
- Wnt-ligand-dependent interaction of TAK1 (TGF-beta-activated kinase-1) with the receptor tyrosine kinase Ror2 modulates canonical Wnt-signalling. 14 Aug 2008
- The human escort protein Hep binds to the ATPase domain of mitochondrial hsp70 and regulates ATP hydrolysis. 14 Jul 2008
- HIV-1 Tat mediates degradation of RON receptor tyrosine kinase, a regulator of inflammation. 13 Jul 2008
- In-cell biochemistry using NMR spectroscopy. 30 Jun 2008
- Effector mechanisms of therapeutic antibodies against ErbB receptors. 29 Jun 2008
- 7-Aminopyrazolo[1,5-a]pyrimidines as potent multitargeted receptor tyrosine kinase inhibitors. 15 Jun 2008
- Identification of nucleolin as new ErbB receptors- interacting protein. 2 Jun 2008
See a longer list of these articles.
Technical information about 'Receptor Protein-Tyrosine Kinases'
Definition: A class of cellular receptors that have an intrinsic PROTEIN-TYROSINE KINASE activity.
Registry Number: EC 2.7.1.112
Descriptor UI: D020794
Alternative terms: Receptor Protein-Tyrosine Kinases; Kinases, Receptor Protein-Tyrosine; Protein-Tyrosine Kinases, Receptor; Receptor Protein Tyrosine Kinases; PTK Receptors; Receptors, PTK; Receptor Protein-Tyrosine Kinase; Kinase, Receptor Protein-Tyrosine; Protein-Tyrosine Kinase, Receptor; Receptor Protein Tyrosine Kinase; Tyrosine Kinase Linked Receptors; Tyrosine Kinase Receptors; Protein-Tyrosine Kinase Receptor; Receptor, Protein-Tyrosine Kinase; Receptors, Protein-Tyrosine Kinase; Protein-Tyrosine Kinase Receptors; Receptors, Protein Tyrosine Kinase;
Allowable Qualifiers: administration & dosage; adverse effects; analysis; antagonists & inhibitors; biosynthesis; blood; cerebrospinal fluid; chemical synthesis; classification; deficiency; diagnostic use; drug effects; economics; genetics; history; immunology; isolation & purification; metabolism; pharmacokinetics; pharmacology; physiology; poisoning; radiation effects; secretion; standards; supply & distribution; therapeutic use; toxicity; ultrastructure; urine; chemistry; contraindications; agonists;
Tree Number: D08.811.913.696.620.682.725.400; D12.776.543.750.060;
History Note: 2000
Technical Notes: DF: PTK RECEPT