Receptor Protein-Tyrosine Kinases - Metabolism
Research News and Information

Saturday, November 21, 2009

The Ron receptor tyrosine kinase is not required for adenoma formation in Apc(Min/+) mice.

30 Oct 2009 The Ron receptor tyrosine kinase is overexpressed in approximately half of all human colon cancers. Increased Ron expression positively correlates with tumor progression, and reduction of Ron levels in human colon adenocarcinoma cells reverses their ... Read more...

Receptor-like kinases shape the plant.

29 Sep 2009 To generate the various tissues and organs that build up the adult body, plants and animals require organized formative cell divisions and correct cell specification. In plants, these processes are controlled mainly by phytohormones and ... Read more...

A role for C. elegans Eph RTK signaling in PTEN regulation.

29 Sep 2009 PTEN is one of the most commonly lost tumor suppressors in human cancer and is known to inhibit insulin signaling. Eph receptor tyrosine kinases (RTKs) have also been implicated in cancer formation and progression, and they have diverse functions, ... Read more...

Latest indexed articles for 'Receptor Protein-Tyrosine Kinases - Metabolism'

These are the very latest articles for this heading:

• The Ron receptor tyrosine kinase is not required for adenoma formation in Apc(Min/+) mice. 30 Oct 2009
• Receptor-like kinases shape the plant. 29 Sep 2009
• A role for C. elegans Eph RTK signaling in PTEN regulation. 29 Sep 2009
• LIG family receptor tyrosine kinase-associated proteins modulate growth factor signals during neural development. 8 Sep 2009
• MMP-9 controls Schwann cell proliferation and phenotypic remodeling via IGF-1 and ErbB receptor-mediated activation of MEK/ERK pathway. 30 Aug 2009
• Proteomic characterization of HIV-modulated membrane receptors, kinases and signaling proteins involved in novel angiogenic pathways. 25 Aug 2009
• The adapter protein SLP-76 mediates "outside-in" integrin signaling and function in T cells. 8 Aug 2009
• A novel role for c-Src and STAT3 in apoptotic cell-mediated MerTK-dependent immunoregulation of dendritic cells. 8 Aug 2009
• Structural recognition of an optimized substrate for the ephrin family of receptor tyrosine kinases. 30 Jul 2009
• Extracorporeal photopheresis-induced immune tolerance: a focus on modulation of antigen-presenting cells and induction of regulatory T cells by apoptotic cells. 30 Jul 2009
• A functional antagonism between the pgc germline repressor and torso in the development of somatic cells. 29 Jul 2009
• Apoptotic cells promote their own clearance and immune tolerance through activation of the nuclear receptor LXR. 28 Jul 2009
• Axl as a potential therapeutic target in cancer: role of Axl in tumor growth, metastasis and angiogenesis. 25 Jul 2009
• Cancer cells harboring MET gene amplification activate alternative signaling pathways to escape MET inhibition but remain sensitive to Hsp90 inhibitors. 25 Jul 2009
• The Mer receptor tyrosine kinase is expressed on discrete macrophage subpopulations and mainly uses Gas6 as its ligand for uptake of apoptotic cells. 22 Jul 2009
• Intermolecular interactions of Sprouty proteins and their implications in development and disease. 29 Jun 2009
• PIKfyve regulation of endosome-linked pathways. 29 Jun 2009
• The kinase defective EPHB6 receptor tyrosine kinase activates MAP kinase signaling in lung adenocarcinoma. 29 Jun 2009
• Comparison of expression profiles of several fibroblast growth factor receptors in the mouse jejunum: suggestive evidence for a differential radioprotective effect among major FGF family members and the potency of FGF1. 29 Jun 2009
• Differential expression of Axl and Gas6 in renal cell carcinoma reflecting tumor advancement and survival. 28 Jun 2009

See a longer list of these articles.

Technical information about 'Receptor Protein-Tyrosine Kinases'

Definition: A class of cellular receptors that have an intrinsic PROTEIN-TYROSINE KINASE activity.

Registry Number: EC 2.7.1.112

Descriptor UI: D020794

Alternative terms: Receptor Protein-Tyrosine Kinases; Kinases, Receptor Protein-Tyrosine; Protein-Tyrosine Kinases, Receptor; Receptor Protein Tyrosine Kinases; PTK Receptors; Receptors, PTK; Receptor Protein-Tyrosine Kinase; Kinase, Receptor Protein-Tyrosine; Protein-Tyrosine Kinase, Receptor; Receptor Protein Tyrosine Kinase; Tyrosine Kinase Linked Receptors; Tyrosine Kinase Receptors; Protein-Tyrosine Kinase Receptor; Receptor, Protein-Tyrosine Kinase; Receptors, Protein-Tyrosine Kinase; Protein-Tyrosine Kinase Receptors; Receptors, Protein Tyrosine Kinase;

Allowable Qualifiers: administration & dosage; adverse effects; analysis; antagonists & inhibitors; biosynthesis; blood; cerebrospinal fluid; chemical synthesis; classification; deficiency; diagnostic use; drug effects; economics; genetics; history; immunology; isolation & purification; metabolism; pharmacokinetics; pharmacology; physiology; poisoning; radiation effects; secretion; standards; supply & distribution; therapeutic use; toxicity; ultrastructure; urine; chemistry; contraindications; agonists;

Tree Number: D08.811.913.696.620.682.725.400; D12.776.543.750.060;

History Note: 2000

Technical Notes: DF: PTK RECEPT