Receptor Protein-Tyrosine Kinases
Research News and Information

Saturday, November 21, 2009

The Ron receptor tyrosine kinase is not required for adenoma formation in Apc(Min/+) mice.

30 Oct 2009 The Ron receptor tyrosine kinase is overexpressed in approximately half of all human colon cancers. Increased Ron expression positively correlates with tumor progression, and reduction of Ron levels in human colon adenocarcinoma cells reverses their ... Read more...

Melanocyte-like cells in the heart and pulmonary veins contribute to atrial arrhythmia triggers.

10 Oct 2009 Atrial fibrillation is the most common clinical cardiac arrhythmia. It is often initiated by ectopic beats arising from the pulmonary veins and atrium, but the source and mechanism of these beats remains unclear. The melanin synthesis enzyme ... Read more...

Receptor-like kinases shape the plant.

29 Sep 2009 To generate the various tissues and organs that build up the adult body, plants and animals require organized formative cell divisions and correct cell specification. In plants, these processes are controlled mainly by phytohormones and ... Read more...

Latest indexed articles for 'Receptor Protein-Tyrosine Kinases'

These are the very latest articles for this heading:

• The Ron receptor tyrosine kinase is not required for adenoma formation in Apc(Min/+) mice. 30 Oct 2009
• Melanocyte-like cells in the heart and pulmonary veins contribute to atrial arrhythmia triggers. 10 Oct 2009
• Receptor-like kinases shape the plant. 29 Sep 2009
• A role for C. elegans Eph RTK signaling in PTEN regulation. 29 Sep 2009
• LIG family receptor tyrosine kinase-associated proteins modulate growth factor signals during neural development. 8 Sep 2009
• The angiopietin-1-Tie2 pathway prevents rather than promotes pulmonary arterial hypertension in transgenic mice. 6 Sep 2009
• Delphinidin inhibits a broad spectrum of receptor tyrosine kinases of the ErbB and VEGFR family. 30 Aug 2009
• MMP-9 controls Schwann cell proliferation and phenotypic remodeling via IGF-1 and ErbB receptor-mediated activation of MEK/ERK pathway. 30 Aug 2009
• Possible neuroprotective effect of brimonidine in a mouse model of ischaemic optic neuropathy. 30 Aug 2009
• Phase I and biomarker study of ABT-869, a multiple receptor tyrosine kinase inhibitor, in patients with refractory solid malignancies. 29 Aug 2009
• Proteomic characterization of HIV-modulated membrane receptors, kinases and signaling proteins involved in novel angiogenic pathways. 25 Aug 2009
• Novel mechanism of lapatinib resistance in HER2-positive breast tumor cells: activation of AXL. 9 Aug 2009
• The adapter protein SLP-76 mediates "outside-in" integrin signaling and function in T cells. 8 Aug 2009
• A novel role for c-Src and STAT3 in apoptotic cell-mediated MerTK-dependent immunoregulation of dendritic cells. 8 Aug 2009
• Survival and migration of human dendritic cells are regulated by an IFN-alpha-inducible Axl/Gas6 pathway. 3 Aug 2009
• Crystal structure of the frizzled-like cysteine-rich domain of the receptor tyrosine kinase MuSK. 2 Aug 2009
• Structural recognition of an optimized substrate for the ephrin family of receptor tyrosine kinases. 30 Jul 2009
• Extracorporeal photopheresis-induced immune tolerance: a focus on modulation of antigen-presenting cells and induction of regulatory T cells by apoptotic cells. 30 Jul 2009
• A functional antagonism between the pgc germline repressor and torso in the development of somatic cells. 29 Jul 2009
• Mer receptor tyrosine kinase is a novel therapeutic target in pediatric B-cell acute lymphoblastic leukemia. 28 Jul 2009

See a longer list of these articles.

Technical information about 'Receptor Protein-Tyrosine Kinases'

Definition: A class of cellular receptors that have an intrinsic PROTEIN-TYROSINE KINASE activity.

Registry Number: EC 2.7.1.112

Descriptor UI: D020794

Alternative terms: Receptor Protein-Tyrosine Kinases; Kinases, Receptor Protein-Tyrosine; Protein-Tyrosine Kinases, Receptor; Receptor Protein Tyrosine Kinases; PTK Receptors; Receptors, PTK; Receptor Protein-Tyrosine Kinase; Kinase, Receptor Protein-Tyrosine; Protein-Tyrosine Kinase, Receptor; Receptor Protein Tyrosine Kinase; Tyrosine Kinase Linked Receptors; Tyrosine Kinase Receptors; Protein-Tyrosine Kinase Receptor; Receptor, Protein-Tyrosine Kinase; Receptors, Protein-Tyrosine Kinase; Protein-Tyrosine Kinase Receptors; Receptors, Protein Tyrosine Kinase;

Allowable Qualifiers: administration & dosage; adverse effects; analysis; antagonists & inhibitors; biosynthesis; blood; cerebrospinal fluid; chemical synthesis; classification; deficiency; diagnostic use; drug effects; economics; genetics; history; immunology; isolation & purification; metabolism; pharmacokinetics; pharmacology; physiology; poisoning; radiation effects; secretion; standards; supply & distribution; therapeutic use; toxicity; ultrastructure; urine; chemistry; contraindications; agonists;

Tree Number: D08.811.913.696.620.682.725.400; D12.776.543.750.060;

History Note: 2000

Technical Notes: DF: PTK RECEPT