Receptor, Serotonin, 5-HT2A
Research News and Information

Saturday, November 21, 2009

Association between the use of serotonin receptor 2A-blocking antidepressants and joint disorders.

13 Oct 2009 OBJECTIVE: There are case reports about antidepressants causing arthritis and arthralgia, and the majority of these reports deal with atypical antidepressants, which are serotonin receptor 2A (5-HT(2A))-blocking substances. The aim of this study was ... Read more...

Mechanisms by which the serotonergic system inhibits micturition in rats.

31 Aug 2009 AIMS: Serotonergic neurons and amino acid neurons are involved in the central nervous control of lower urinary tract function. We investigated the role of the serotonergic system in the central regulation of micturition, as well as the relationship ... Read more...

[Serotonin receptor gene polymorphism and analgesic sensitivity]

30 Aug 2009 There are gene polymorphisms changing the expression or activation of the serotonin (5-HT) receptors, which are associated with pain. This review showed an availability of 5-HT2A receptor gene polymorphism in analgesic sensitivity. To search gene ... Read more...

Latest indexed articles for 'Receptor, Serotonin, 5-HT2A'

These are the very latest articles for this heading:

• Association between the use of serotonin receptor 2A-blocking antidepressants and joint disorders. 13 Oct 2009
• Mechanisms by which the serotonergic system inhibits micturition in rats. 31 Aug 2009
• [Serotonin receptor gene polymorphism and analgesic sensitivity] 30 Aug 2009
• [Pharmacological studies on responsiveness of 5-hydroxytryptamine in overcoming perioperative spasm of coronary artery bypass graft] 30 Aug 2009
• Autoantibodies, polymorphisms in the serotonin pathway, and human leukocyte antigen class II alleles in chronic fatigue syndrome: are they associated with age at onset and specific symptoms? 30 Aug 2009
• 5-HT 1A and 2A receptor positive cells in the cerebella of mice and human and their decline during aging. 30 Aug 2009
• Inhibitory effect of serotonin antagonists on JC virus propagation in a carrier culture of human neuroblastoma cells. 30 Aug 2009
• Chronic treatment of hydroxytryptamine type 2a receptor antagonist sarpogrelate hydrochloride modulates the vasoreactivity of serotonin in experimental rabbit vein grafts. 30 Aug 2009
• Regional distribution and behavioral correlates of 5-HT(2A) receptors in Alzheimer's disease with [(18)F]deuteroaltanserin and PET. 11 Aug 2009
• 5-HTR1A, 5-HTR2A, 5-HTR6, TPH1 and TPH2 polymorphisms and major depression. 3 Aug 2009
• [Influence of serotonin (5-HT) 2A-receptor and transporter (5HTT) gene polymorphism upon the effect of olanzapine] 30 Jul 2009
• Expression of placental serotonin transporter and 5-HT 2A receptor in normal and gestational diabetes mellitus pregnancies. 30 Jul 2009
• Assessment of binding affinity to 5-hydroxytryptamine 2A (5-HT2A) receptor and inverse agonist activity of naftidrofuryl: comparison with those of sarpogrelate. 30 Jul 2009
• No association between lithium full responders and the DRD1, DRD2, DRD3, DAT1, 5-HTTLPR and HTR2A genes in a Sardinian sample. 29 Jul 2009
• APD791, 3-methoxy-n-(3-(1-methyl-1h-pyrazol-5-yl)-4-(2-morpholinoethoxy)phenyl)benzamide, a novel 5-hydroxytryptamine 2A receptor antagonist: pharmacological profile, pharmacokinetics, platelet activity and vascular biology. 21 Jul 2009
• Implication of the 5-HT2A and 5-HT2C (but not 5HT1A) receptors located within the periaqueductal gray in the elevated plus-maze test-retest paradigm in mice. 17 Jul 2009
• Locomotor-activated neurons of the cat. I. Serotonergic innervation and co-localization of 5-HT7, 5-HT2A, and 5-HT1A receptors in the thoraco-lumbar spinal cord. 29 Jun 2009
• Decrease in the kainate-induced wet dog shake behavior in genetically epilepsy-prone rats: possible involvement of an impaired synaptic transmission to the 5-HT(2A) receptor. 29 Jun 2009
• Conceptualizing autism: the role for emergence. 29 Jun 2009
• Sensorimotor gating depends on polymorphisms of the serotonin-2A receptor and catechol-O-methyltransferase, but not on neuregulin-1 Arg38Gln genotype: a replication study. 26 Jun 2009

See a longer list of these articles.

Technical information about 'Receptor, Serotonin, 5-HT2A'

Definition: A serotonin receptor subtype found widely distributed in peripheral tissues where it mediates the contractile responses of variety of tissues that contain SMOOTH MUSCLE. Selective 5-HT2A receptor antagonists include KETANSERIN. The 5-HT2A subtype is also located in BASAL GANGLIA and CEREBRAL CORTEX of the BRAIN where it mediates the effects of HALLUCINOGENS such as LSD.

Registry Number: 0

Descriptor UI: D044402

Alternative terms: Receptor, Serotonin, 5-HT2A; 5-HT2A Receptor; 5 HT2A Receptor; Receptor, 5-HT2A; Serotonin 2A Receptors; 2A Receptors, Serotonin; Receptors, Serotonin 2A; Serotonin 2A Receptor; 5-HT(2A) Receptor; Receptor, Serotonin 2A; 2A Receptor, Serotonin;

Allowable Qualifiers: administration & dosage; analysis; antagonists & inhibitors; biosynthesis; blood; classification; deficiency; drug effects; genetics; history; immunology; isolation & purification; metabolism; physiology; radiation effects; therapeutic use; ultrastructure; chemistry; agonists;

Tree Number: D12.776.543.750.070.800.200.100; D12.776.543.750.100.800.200.100; D12.776.543.750.720.300.800.200.100;

History Note: 2004; use RECEPTOR, SEROTONIN, 5-HT2A (NM) 1994-2003