Receptors, Adenosine A2 - Genetics
Research News and Information

Tuesday, November 24, 2009

Adenosine A2A receptors enable the synaptic effects of cannabinoid CB1 receptors in the rodent striatum.

15 Jul 2009 Adenosine A(2A), cannabinoid CB(1) and metabotropic glutamate 5 (mGlu(5)) receptors are all highly expressed in the striatum. The aim of the present work was to investigate whether, and by which mechanisms, the above receptors interact in the ... Read more...

New bioinformatics approach to analyze gene expressions and signaling pathways reveals unique purine gene dysregulation profiles that distinguish between CD and UC.

29 Jun 2009 BACKGROUND: Expression of purine genes is modulated by inflammation or experimental colitis and altered expression leads to disrupted gut function. We studied purine gene dysregulation profiles in inflammatory bowel disease (IBD) and determined ... Read more...

Adenosine A2A receptor is a unique angiogenic target of HIF-2alpha in pulmonary endothelial cells.

15 Jun 2009 Hypoxia, through the hypoxia-inducible transcription factors HIF-1alpha and HIF-2alpha (HIFs), induces angiogenesis by up-regulating a common set of angiogenic cytokines. Unlike HIF-1alpha, which regulates a unique set of genes, most genes regulated ... Read more...

Latest indexed articles for 'Receptors, Adenosine A2 - Genetics'

These are the very latest articles for this heading:

• Adenosine A2A receptors enable the synaptic effects of cannabinoid CB1 receptors in the rodent striatum. 15 Jul 2009
• New bioinformatics approach to analyze gene expressions and signaling pathways reveals unique purine gene dysregulation profiles that distinguish between CD and UC. 29 Jun 2009
• Adenosine A2A receptor is a unique angiogenic target of HIF-2alpha in pulmonary endothelial cells. 15 Jun 2009
• D2R striatopallidal neurons inhibit both locomotor and drug reward processes. 6 Mar 2009
• Identification of zebrafish A2 adenosine receptors and expression in developing embryos. Dec 2008
• Mice heterozygous for both A1 and A(2A) adenosine receptor genes show similarities to mice given long-term caffeine. 24 Nov 2008
• Diminished iron concentrations increase adenosine A(2A) receptor levels in mouse striatum and cultured human neuroblastoma cells. 26 Oct 2008
• Adenosine A2A receptor hyperexpression in patients with severe SIRS after cardiopulmonary bypass. 30 Jul 2008
• Polymorphisms within the adenosine receptor 2a gene are associated with adverse events in RA patients treated with MTX. 4 Jun 2008
• [Establishment and evaluation of brain adenosine A2A receptors inactivation model of mice] 30 Mar 2008
• Hypoxia suppresses the production of MMP-9 by human monocyte-derived dendritic cells and requires activation of adenosine receptor A2b via cAMP/PKA signaling pathway. 20 Jan 2008
• Adenosine receptors in rat and human pancreatic ducts stimulate chloride transport. 3 Dec 2007
• Chronic but not acute treatment with caffeine attenuates traumatic brain injury in the mouse cortical impact model. 26 Nov 2007
• Regulation of A(2A) adenosine receptor expression and functioning following permanent focal ischemia in rat brain. 20 Oct 2007
• Genetic polymorphism of the adenosine A2A receptor is associated with habitual caffeine consumption. 29 Jun 2007
• Relationship between A2A adenosine receptor expression and intradialytic hypotension during hemodialysis. 29 Nov 2006
• Reduced response to the formalin test and lowered spinal NMDA glutamate receptor binding in adenosine A2A receptor knockout mice. 26 Nov 2006
• Presynaptic control of striatal glutamatergic neurotransmission by adenosine A1-A2A receptor heteromers. 13 Feb 2006
• Adenosine A2A receptors are expressed by GABAergic neurons of medulla oblongata in developing rat. 15 Jan 2006
• Luminal adenosine stimulates chloride secretion through A1 receptor in mouse jejunum. 4 Jan 2005

See a longer list of these articles.

Technical information about 'Receptors, Adenosine A2'

Definition: A subclass of ADENOSINE RECEPTORS that are generally considered to be coupled to the GS, STIMULATORY G-PROTEIN which causes up regulation of CYCLIC AMP.

Registry Number: 0

Descriptor UI: D043683

Alternative terms: Receptors, Adenosine A2; A2 Receptors, Adenosine; Adenosine A2 Receptors; Adenosine A2 Receptor; A2 Receptor, Adenosine; Receptor, Adenosine A2;

Allowable Qualifiers: administration & dosage; analysis; antagonists & inhibitors; biosynthesis; blood; classification; deficiency; drug effects; genetics; history; immunology; isolation & purification; metabolism; physiology; radiation effects; therapeutic use; ultrastructure; chemistry; agonists;

Tree Number: D12.776.543.750.100.700.700.200; D12.776.543.750.720.700.700.200; D12.776.543.750.810.700.200;

History Note: 2004; use RECEPTORS, PURINERGIC P1 1994-2003