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Receptors, Adrenergic, alpha-1 - Genetics
Research News and Information
Definition of 'Receptors, Adrenergic, alpha-1'A subclass of alpha-adrenergic receptors (RECEPTORS, ADRENERGIC, ALPHA). alpha-1 Adrenergic receptors can be pharmacologically discriminated, e.g., by their high affinity for the agonist phenylephrine and the antagonist prazosin. They are widespread, with clinically important concentrations in the liver, the heart, vascular, intestinal, and genitourinary smooth muscle, and the central and peripheral nervous systems. |
Monday, November 23, 2009
29 Sep 2009 
BACKGROUND: Recently, alpha(1)-adrenoceptors (alpha(1)-ARs) have been reported to play a prominent role in the growth of a variety of cells; however, little is known about prostate growth and subtype-specific effects on cell proliferation. We ... Read more...
20 Sep 2009 OBJECTIVES: The goal was to identify alpha-1-adrenergic receptor (AR) subtypes in human coronary arteries. BACKGROUND: The alpha1-ARs regulate human coronary blood flow. The alpha1-ARs exist as 3 molecular subtypes, alpha1A, alpha1B, and alpha1D, ... Read more...
DNA synthesis of rat bone marrow mesenchymal stem cells through alpha1-adrenergic receptors.
16 Aug 2009 Multipotential bone marrow mesenchymal stem cells (BMSCs) are important in maintaining the microenvironment of the bone marrow (BM). Sympathetic nerves histologically innervate the BM; however, their role remains unclear. In this study, the effects ... Read more...
Latest indexed articles for 'Receptors, Adrenergic, alpha-1 - Genetics'
These are the very latest articles for this heading:
- Prostate growth inhibition by subtype-selective alpha(1)-adrenoceptor antagonist naftopidil in benign prostatic hyperplasia. 29 Sep 2009
- The alpha-1D Is the predominant alpha-1-adrenergic receptor subtype in human epicardial coronary arteries. 20 Sep 2009
- DNA synthesis of rat bone marrow mesenchymal stem cells through alpha1-adrenergic receptors. 16 Aug 2009
- Protein tyrosine phosphatase 1B, a major regulator of leptin-mediated control of cardiovascular function. 15 Aug 2009
- Hypophosphatemia-mediated hypotension in transgenic mice overexpressing human FGF-23. 12 Aug 2009
- Association of adrenergic receptor gene polymorphisms with different fibromyalgia syndrome domains. 29 Jun 2009
- Alteration of messenger RNA and protein levels of cardiac alpha(1)-adrenergic receptor and angiotensin II receptor subtypes during aging in rats. 29 Jun 2009
- Functional alpha1- and beta2-adrenergic receptors in human osteoblasts. 29 Jun 2009
- alpha1-Adrenergic receptors regulate neurogenesis and gliogenesis. 30 May 2009
- Candidate gene analysis in an on-going genome-wide association study of attention-deficit hyperactivity disorder: suggestive association signals in ADRA1A. 30 May 2009
- Blockade of alpha 1A-adrenoceptor: a novel possible strategy for male contraception. 6 May 2009
- Mechanical function and gene expression of alpha(1)-adrenoceptor subtypes in dog intravesical ureter. 13 Apr 2009
- Genetic variation in the autonomic nervous system affects mortality: a study of 1,095 trauma patients. 24 Mar 2009
- Complex cardiovascular actions of alpha-adrenergic receptors expressed in the nucleus tractus solitarii of rats. 16 Mar 2009
- Temporally precise in vivo control of intracellular signalling. 16 Mar 2009
- Effects of lactational exposure to benzo[alpha]pyrene (B[alpha]P) on postnatal neurodevelopment, neuronal receptor gene expression and behaviour in mice. 2 Mar 2009
- Enhanced vascular contractility in alpha1-adrenergic receptor-deficient mice. 24 Feb 2009
- Adenosine receptors and second messenger signaling pathways in rat cardiac fibroblasts. 23 Feb 2009
- Lack of alpha 1b-adrenergic receptor protects against epileptic seizures. 30 Dec 2008
- Electrical remodeling in a transgenic mouse model of alpha1B-adrenergic receptor overexpression. 24 Dec 2008
See a longer list of these articles.
Technical information about 'Receptors, Adrenergic, alpha-1'
Definition: A subclass of alpha-adrenergic receptors (RECEPTORS, ADRENERGIC, ALPHA). alpha-1 Adrenergic receptors can be pharmacologically discriminated, e.g., by their high affinity for the agonist phenylephrine and the antagonist prazosin. They are widespread, with clinically important concentrations in the liver, the heart, vascular, intestinal, and genitourinary smooth muscle, and the central and peripheral nervous systems.
Registry Number: 0
Descriptor UI: D018340
Alternative terms: Receptors, Adrenergic, alpha-1; Receptor, Adrenergic, alpha-1; alpha 1 Adrenergic Receptor; Adrenergic alpha-1 Receptors; Adrenergic alpha 1 Receptors; Receptors, Adrenergic alpha-1; alpha-1 Receptors, Adrenergic; Receptors, alpha-1 Adrenergic; Receptors, alpha 1 Adrenergic; Adrenergic Receptor, alpha-1; Adrenergic Receptor, alpha 1; Receptor, alpha-1 Adrenergic; alpha-1 Adrenergic Receptor; alpha-1 Adrenergic Receptors; Adrenergic Receptors, alpha-1; alpha 1 Adrenergic Receptors;
Allowable Qualifiers: administration & dosage; analysis; antagonists & inhibitors; biosynthesis; blood; classification; deficiency; drug effects; genetics; history; immunology; isolation & purification; metabolism; physiology; radiation effects; therapeutic use; ultrastructure; chemistry; agonists;
Tree Number: D12.776.543.750.070.300.300.300.700; D12.776.543.750.100.150.300.300.700; D12.776.543.750.720.300.300.300.300.100;
History Note: 94