Receptors, Adrenergic, beta - Drug effects
Research News and Information

Sunday, November 22, 2009

Molecular mechanisms of combination therapy with inhaled corticosteroids and long-acting beta-agonists.

29 Sep 2009 The treatment of asthma relies on the use of the following two major drug classes: beta(2)-agonists, both short acting and long acting; and corticosteroids (CSs). Although the properties of each drug class are well described, their use in ... Read more...

Regulation of VASP phosphorylation in cardiac myocytes: differential regulation by cyclic nucleotides and modulation of protein expression in diabetic and hypertrophic heart.

2 Sep 2009 Vasodilator-stimulated phosphoprotein (VASP) is a major substrate for cyclic nucleotide-dependent kinases that has been implicated in cardiac pathology, yet many aspects of VASP's molecular regulation in cardiomyocytes are incompletely understood. ... Read more...

Suppression of collagen production in norepinephrine stimulated cardiac fibroblasts culture: differential effect of alpha and beta-adrenoreceptor antagonism.

30 Jul 2009 OBJECTIVES: Prolonged sympathetic activation is damaging to the heart and experimental norepinephrine (NE) infusion induces the deposition of myocardial collagen. This study investigated the effects of NE on collagen and transforming growth ... Read more...

Latest indexed articles for 'Receptors, Adrenergic, beta - Drug effects'

These are the very latest articles for this heading:

• Molecular mechanisms of combination therapy with inhaled corticosteroids and long-acting beta-agonists. 29 Sep 2009
• Regulation of VASP phosphorylation in cardiac myocytes: differential regulation by cyclic nucleotides and modulation of protein expression in diabetic and hypertrophic heart. 2 Sep 2009
• Suppression of collagen production in norepinephrine stimulated cardiac fibroblasts culture: differential effect of alpha and beta-adrenoreceptor antagonism. 30 Jul 2009
• Clinical and genetic modifiers of long-term survival in heart failure. 26 Jul 2009
• Use of fat-fed rats to study the metabolic and vascular sequelae of obesity and beta-adrenergic antagonism. 30 May 2009
• NO production and eNOS phosphorylation induced by epinephrine through the activation of beta-adrenoceptors. 6 May 2009
• Alpha and beta noradrenergic mediation of NMDA glutamatergic effects on lordosis behaviour and plasmatic LH concentrations in the primed female rat. 22 Apr 2009
• Surgical stress promotes tumor growth in ovarian carcinoma. 5 Apr 2009
• Novel pharmacotherapies to abrogate postinfarction ventricular remodeling. 30 Mar 2009
• CpG-C oligodeoxynucleotides limit the deleterious effects of beta-adrenoceptor stimulation on NK cytotoxicity and metastatic dissemination. 30 Mar 2009
• Noradrenaline reduces the ATP-stimulated phosphorylation of p38 MAP kinase via beta-adrenergic receptors-cAMP-protein kinase A-dependent mechanism in cultured rat spinal microglia. 16 Mar 2009
• Antioxidants but not doxycycline treatments restore depressed beta-adrenergic responses of the heart in diabetic rats. 16 Mar 2009
• Chronic beta-AR activation-induced calpain activation and impaired eNOS-Akt signaling mediates cardiac injury in ovariectomized female rats. 27 Feb 2009
• Does adenosine A(1) receptor stimulation causes QRS prolongation by blocking beta adrenergic receptors in amitriptyline poisoning? 18 Jan 2009
• Chloroform extract of cigarette smoke induces proliferation of human esophageal squamous-cell carcinoma cells: modulation by beta-adrenoceptors. 30 Dec 2008
• Gene profiling of left ventricle eccentric hypertrophy in aortic regurgitation in rats: rationale for targeting the beta-adrenergic and renin-angiotensin systems. 24 Dec 2008
• New perspectives on beta-adrenergic mediation of innate and learned fear responses to predator odor. Dec 2008
• Beta-adrenergic receptor regulation of growth factor protein levels in human choroidal endothelial cells. 29 Nov 2008
• Importance of adrenergic receptors in prenatally induced cognitive impairment in the domestic chick. 3 Nov 2008
• The reboxetine-induced increase of accumbal dopamine efflux is inhibited by l-propranolol: a microdialysis study with freely moving rats. 3 Nov 2008

See a longer list of these articles.

Technical information about 'Receptors, Adrenergic, beta'

Definition: One of the two major pharmacologically defined classes of adrenergic receptors. The alpha-beta distinction was originally based on the cellular effects of receptor activation but now relies on the relative affinities for characteristic synthetic ligands. Beta adrenergic receptors are further subdivided based on information from endogenous and cloned receptors.

Registry Number: 0

Descriptor UI: D011943

Alternative terms: Receptors, Adrenergic, beta; Receptor, Adrenergic, beta; Receptors, beta-Adrenergic; Receptors, beta Adrenergic; Adrenergic beta-Receptors; Adrenergic beta Receptors; beta-Receptors, Adrenergic; beta-Adrenergic Receptors; beta Adrenergic Receptors;

Allowable Qualifiers: administration & dosage; analysis; biosynthesis; blood; classification; deficiency; drug effects; genetics; history; immunology; isolation & purification; metabolism; physiology; radiation effects; therapeutic use; ultrastructure; chemistry;

Tree Number: D12.776.543.750.070.300.300.340; D12.776.543.750.100.150.300.340; D12.776.543.750.720.300.300.300.340;

History Note: 84(77); was see under RECEPTORS, ADRENERGIC 1977-83

Technical Notes: coord IM with specific beta adrenergic agent (IM); DF: ADREN BETA RECEPT