Receptors, Adrenergic, beta
Research News and Information

Sunday, November 22, 2009

Molecular mechanisms of combination therapy with inhaled corticosteroids and long-acting beta-agonists.

29 Sep 2009 The treatment of asthma relies on the use of the following two major drug classes: beta(2)-agonists, both short acting and long acting; and corticosteroids (CSs). Although the properties of each drug class are well described, their use in ... Read more...

The alpha-1D Is the predominant alpha-1-adrenergic receptor subtype in human epicardial coronary arteries.

20 Sep 2009 OBJECTIVES: The goal was to identify alpha-1-adrenergic receptor (AR) subtypes in human coronary arteries. BACKGROUND: The alpha1-ARs regulate human coronary blood flow. The alpha1-ARs exist as 3 molecular subtypes, alpha1A, alpha1B, and alpha1D, ... Read more...

Regulation of VASP phosphorylation in cardiac myocytes: differential regulation by cyclic nucleotides and modulation of protein expression in diabetic and hypertrophic heart.

2 Sep 2009 Vasodilator-stimulated phosphoprotein (VASP) is a major substrate for cyclic nucleotide-dependent kinases that has been implicated in cardiac pathology, yet many aspects of VASP's molecular regulation in cardiomyocytes are incompletely understood. ... Read more...

Latest indexed articles for 'Receptors, Adrenergic, beta'

These are the very latest articles for this heading:

• Perioperative strokes and beta-blockade. 30 Oct 2009
• Molecular mechanisms of combination therapy with inhaled corticosteroids and long-acting beta-agonists. 29 Sep 2009
• The best "model system" for human (coronary arteries) is human. 20 Sep 2009
• The alpha-1D Is the predominant alpha-1-adrenergic receptor subtype in human epicardial coronary arteries. 20 Sep 2009
• Regulation of VASP phosphorylation in cardiac myocytes: differential regulation by cyclic nucleotides and modulation of protein expression in diabetic and hypertrophic heart. 2 Sep 2009
• Chronic administration of KB-R7943 induces up-regulation of cardiac NCX1. 4 Aug 2009
• Suppression of collagen production in norepinephrine stimulated cardiac fibroblasts culture: differential effect of alpha and beta-adrenoreceptor antagonism. 30 Jul 2009
• Expression of alpha1-adrenoceptors on thymic cells and their role in fine tuning of thymopoiesis. 28 Jul 2009
• Clinical and genetic modifiers of long-term survival in heart failure. 26 Jul 2009
• Beta-adrenoceptor stimulation of alveolar fluid clearance is increased in rats with heart failure. 8 Jul 2009
• Chronic intermittent hypoxia increases left ventricular contractility in C57BL/6J mice. 7 Jul 2009
• Cardiac myocytes derived from murine reprogrammed fibroblasts: intact hormonal regulation, cardiac ion channel expression and development of contractility. 29 Jun 2009
• Regulation of basal and reserve cardiac pacemaker function by interactions of cAMP-mediated PKA-dependent Ca2+ cycling with surface membrane channels. 28 Jun 2009
• The potential beneficial effects of beta adrenergic blockade in the treatment of ventricular fibrillation. 21 Jun 2009
• Discovery of novel thiourea derivatives as potent and selective beta3-adrenergic receptor agonists. 19 Jun 2009
• Zebrafish beta-adrenergic receptor mRNA expression and control of pigmentation. 16 Jun 2009
• Involvement of the beta-adrenergic system in the cardiac chronic form of experimental Trypanosoma cruzi infection. 13 Jun 2009
• Loss of M2 muscarinic receptor function inhibits development of hypoxic bradycardia and alters cardiac beta-adrenergic sensitivity in larval zebrafish (Danio rerio). 8 Jun 2009
• Adrenergic activation of electrogenic K+ secretion in guinea pig distal colonic epithelium: desensitization via the Y2-neuropeptide receptor. 2 Jun 2009
• Regulation of the Src homology 2 domain-containing inositol 5'-phosphatase (SHIP1) by the cyclic AMP-dependent protein kinase. Jun 2009

See a longer list of these articles.

Technical information about 'Receptors, Adrenergic, beta'

Definition: One of the two major pharmacologically defined classes of adrenergic receptors. The alpha-beta distinction was originally based on the cellular effects of receptor activation but now relies on the relative affinities for characteristic synthetic ligands. Beta adrenergic receptors are further subdivided based on information from endogenous and cloned receptors.

Registry Number: 0

Descriptor UI: D011943

Alternative terms: Receptors, Adrenergic, beta; Receptor, Adrenergic, beta; Receptors, beta-Adrenergic; Receptors, beta Adrenergic; Adrenergic beta-Receptors; Adrenergic beta Receptors; beta-Receptors, Adrenergic; beta-Adrenergic Receptors; beta Adrenergic Receptors;

Allowable Qualifiers: administration & dosage; analysis; biosynthesis; blood; classification; deficiency; drug effects; genetics; history; immunology; isolation & purification; metabolism; physiology; radiation effects; therapeutic use; ultrastructure; chemistry;

Tree Number: D12.776.543.750.070.300.300.340; D12.776.543.750.100.150.300.340; D12.776.543.750.720.300.300.300.340;

History Note: 84(77); was see under RECEPTORS, ADRENERGIC 1977-83

Technical Notes: coord IM with specific beta adrenergic agent (IM); DF: ADREN BETA RECEPT