Receptors, Cell Surface - Genetics
Research News and Information

Monday, November 23, 2009

Equal contribution of increased intracranial pressure and subarachnoid blood to cerebral blood flow reduction and receptor upregulation after subarachnoid hemorrhage. Laboratory investigation.

30 Oct 2009 OBJECT: Cerebral ischemia remains the key cause of disability and death in the late phase after subarachnoid hemorrhage (SAH), and its pathogenesis is still poorly understood. The purpose of this study was to examine whether the change in ... Read more...

EIN2, the central regulator of ethylene signalling, is localized at the ER membrane where it interacts with the ethylene receptor ETR1.

21 Oct 2009 Genetic studies have identified the membrane protein EIN2 (ethylene insensitive 2) as a central component of ethylene signalling in Arabidopsis. In addition, EIN2 might take part in multiple hormone signalling pathways and in response to pathogens ... Read more...

Patched 1 is a crucial determinant of asymmetry and digit number in the vertebrate limb.

29 Sep 2009 The vertebrate hedgehog receptor patched 1 (Ptc1) is crucial for negative regulation of the sonic hedgehog (Shh) pathway during anterior-posterior patterning of the limb. We have conditionally inactivated Ptc1 in the mesenchyme of the mouse limb ... Read more...

Latest indexed articles for 'Receptors, Cell Surface - Genetics'

These are the very latest articles for this heading:

• Equal contribution of increased intracranial pressure and subarachnoid blood to cerebral blood flow reduction and receptor upregulation after subarachnoid hemorrhage. Laboratory investigation. 30 Oct 2009
• EIN2, the central regulator of ethylene signalling, is localized at the ER membrane where it interacts with the ethylene receptor ETR1. 21 Oct 2009
• [Genetics in chronic obstructive pulmonary disease] 20 Oct 2009
• Patched 1 is a crucial determinant of asymmetry and digit number in the vertebrate limb. 29 Sep 2009
• Endogenous Jmjd6 gene product is expressed at the cell surface and regulates phagocytosis in immature monocyte-like activated THP-1 cells. 29 Sep 2009
• Essential roles for Dok2 and RasGAP in CD200 receptor-mediated regulation of human myeloid cells. 26 Sep 2009
• Endothelial protein C receptor is expressed in rat cortical and hippocampal neurons and is necessary for protective effect of activated protein C at glutamate excitotoxicity. 23 Sep 2009
• Pathogenicity of a disease-associated human IL-4 receptor allele in experimental asthma. 19 Sep 2009
• Identification of functional LsrB-like autoinducer-2 receptors. 9 Sep 2009
• The plasmodium receptor for activated C kinase protein inhibits Ca(2+) signaling in mammalian cells. 9 Sep 2009
• Activation of sonic hedgehog signaling pathway in olfactory neuroblastoma. 5 Sep 2009
• Brassinosteroid signal transduction from cell-surface receptor kinases to nuclear transcription factors. 4 Sep 2009
• Following the hedgehog to new cancer therapies. 31 Aug 2009
• Inhibition of the hedgehog pathway in advanced basal-cell carcinoma. 31 Aug 2009
• Treatment of medulloblastoma with hedgehog pathway inhibitor GDC-0449. 31 Aug 2009
• Folate receptor alpha defect causes cerebral folate transport deficiency: a treatable neurodegenerative disorder associated with disturbed myelin metabolism. 30 Aug 2009
• Crystal structure of the plexin A3 intracellular region reveals an autoinhibited conformation through active site sequestration. 24 Aug 2009
• Multiple feedback loops through cytokinin signaling control stem cell number within the Arabidopsis shoot meristem. 24 Aug 2009
• Identification of 4 new HLA-DR-restricted minor histocompatibility antigens as hematopoietic targets in antitumor immunity. 23 Aug 2009
• Cilium-independent regulation of Gli protein function by Sufu in Hedgehog signaling is evolutionarily conserved. 13 Aug 2009

See a longer list of these articles.

Technical information about 'Receptors, Cell Surface'

Definition: Cell surface proteins that bind signalling molecules external to the cell with high affinity and convert this extracellular event into one or more intracellular signals that alter the behavior of the target cell (From Alberts, Molecular Biology of the Cell, 2nd ed, pp693-5). Cell surface receptors, unlike enzymes, do not chemically alter their ligands.

Registry Number: 0

Descriptor UI: D011956

Alternative terms: Receptors, Cell Surface; Cell Surface Receptors; Hormone Receptors, Cell Surface; Cell Surface Hormone Receptors; Endogenous Substances Receptors; Receptors, Endogenous Substances;

Allowable Qualifiers: administration & dosage; analysis; antagonists & inhibitors; biosynthesis; blood; classification; deficiency; drug effects; genetics; history; immunology; isolation & purification; metabolism; physiology; radiation effects; therapeutic use; ultrastructure; chemistry; agonists;

Tree Number: D12.776.543.750;

Online Note: use RECEPTORS, CELL SURFACE to search RECEPTORS, ENDOGENOUS SUBSTANCES 1983-93, CELL RECEPTORS 1985-93, HORMONE RECEPTORS 1975-93, RECEPTORS BIOLOGICAL 1985-93, & RECEPTORS, HORMONE 1973-93

History Note: 94; was RECEPTORS, ENDOGENOUS SUBSTANCES 1983-93; was RECEPTORS, HORMONE 1973-82; CELL RECEPTORS & RECEPTORS, BIOLOGIC were see RECEPTORS, ENDOGENOUS SUBSTANCES 1985-93; HORMONE RECEPTORS was see RECEPTORS, ENDOGENOUS SUBSTANCES 1975-93

Technical Notes: GEN: prefer specifics; coord IM with specific endogenous substance (IM); for hormone receptors in general coord HORMONES (IM) + RECEPTORS, CELL SURFACE (IM) or RECEPTORS, CYTOPLASMIC AND NUCLEAR (IM), for receptors of specific hormones, coord specific hormone or hormone group (IM) + precoord hormone receptor (e.g., RECEPTORS, ALDOSTERONE) (IM) or precoord hormone-group receptor (e.g., RECEPTORS, GLUCOCORTICOID) (IM); DF: RECEPT CELL SURFACE