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Receptors, Cell Surface
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Definition of 'Receptors, Cell Surface'

Cell surface proteins that bind signalling molecules external to the cell with high affinity and convert this extracellular event into one or more intracellular signals that alter the behavior of the target cell (From Alberts, Molecular Biology of the Cell, 2nd ed, pp693-5). Cell surface receptors, unlike enzymes, do not chemically alter their ligands.

Common names: Receptors, Cell Surface; Cell Surface Receptors; Hormone Receptors, Cell Surface; Cell Surface Hormone Receptors; Endogenous Substances Receptors; Receptors, Endogenous Substances

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Monday, November 23, 2009

Diagnostic value of CD163 in cutaneous spindle cell lesions.

22 Nov 2009 BACKGROUND: The histologic diagnosis of atypical fibroxanthoma (AFX) can sometimes be challenging. No specific marker exists to confirm the diagnosis other than excluding other entities. CD163 has been shown to have great specificity for tumors of ... Read more...


Direct interaction between anthrax toxin receptor 1 and the actin cytoskeleton.

8 Nov 2009 The protective antigen component of anthrax toxin binds the I domain of the anthrax toxin receptors, ANTXR1 and ANTXR2, in a manner akin to how integrins bind their ligands. The I domains of integrins and ANTXR1 both have high- and low-affinity ... Read more...


Equal contribution of increased intracranial pressure and subarachnoid blood to cerebral blood flow reduction and receptor upregulation after subarachnoid hemorrhage. Laboratory investigation.

30 Oct 2009 OBJECT: Cerebral ischemia remains the key cause of disability and death in the late phase after subarachnoid hemorrhage (SAH), and its pathogenesis is still poorly understood. The purpose of this study was to examine whether the change in ... Read more...

 

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Technical information about 'Receptors, Cell Surface'

Definition: Cell surface proteins that bind signalling molecules external to the cell with high affinity and convert this extracellular event into one or more intracellular signals that alter the behavior of the target cell (From Alberts, Molecular Biology of the Cell, 2nd ed, pp693-5). Cell surface receptors, unlike enzymes, do not chemically alter their ligands.

Registry Number: 0

Descriptor UI: D011956

Alternative terms: Receptors, Cell Surface; Cell Surface Receptors; Hormone Receptors, Cell Surface; Cell Surface Hormone Receptors; Endogenous Substances Receptors; Receptors, Endogenous Substances;

Allowable Qualifiers: administration & dosage; analysis; antagonists & inhibitors; biosynthesis; blood; classification; deficiency; drug effects; genetics; history; immunology; isolation & purification; metabolism; physiology; radiation effects; therapeutic use; ultrastructure; chemistry; agonists;

Tree Number: D12.776.543.750;

Online Note: use RECEPTORS, CELL SURFACE to search RECEPTORS, ENDOGENOUS SUBSTANCES 1983-93, CELL RECEPTORS 1985-93, HORMONE RECEPTORS 1975-93, RECEPTORS BIOLOGICAL 1985-93, & RECEPTORS, HORMONE 1973-93

History Note: 94; was RECEPTORS, ENDOGENOUS SUBSTANCES 1983-93; was RECEPTORS, HORMONE 1973-82; CELL RECEPTORS & RECEPTORS, BIOLOGIC were see RECEPTORS, ENDOGENOUS SUBSTANCES 1985-93; HORMONE RECEPTORS was see RECEPTORS, ENDOGENOUS SUBSTANCES 1975-93

Technical Notes: GEN: prefer specifics; coord IM with specific endogenous substance (IM); for hormone receptors in general coord HORMONES (IM) + RECEPTORS, CELL SURFACE (IM) or RECEPTORS, CYTOPLASMIC AND NUCLEAR (IM), for receptors of specific hormones, coord specific hormone or hormone group (IM) + precoord hormone receptor (e.g., RECEPTORS, ALDOSTERONE) (IM) or precoord hormone-group receptor (e.g., RECEPTORS, GLUCOCORTICOID) (IM); DF: RECEPT CELL SURFACE

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