Receptors, Cholinergic - Metabolism
Research News and Information

Saturday, November 21, 2009

Alterations in cholinergic sensitivity of respiratory neurons induced by pre-natal nicotine: a mechanism for respiratory dysfunction in neonatal mice.

10 Sep 2009 Nicotine may link cigarette smoking during pregnancy with sudden infant death syndrome (SIDS). Pre-natal nicotine leads to diminished ventilatory responses to hypercarbia and reduced central chemoreception in mice at post-natal days 0-3. We studied ... Read more...

Boosting cholinergic activity in gustatory cortex enhances the salience of a familiar conditioned stimulus in taste aversion learning.

30 Jul 2009 The cholinergic system is important for learning, memory, and responses to novel stimuli. Exposure to novel, but not familiar, tastes increases extracellular acetylcholine (ACh) levels in insular cortex (IC). To further examine whether cholinergic ... Read more...

Acetylcholine receptor pathway and lung cancer.

30 Jul 2009 Genome-wide association studies revealed chromosome regions 15q24-25 were associated with a higher risk for development of lung cancer. The 15q24-25 region encompasses the nicotinic acetylcholine receptor subunit genes (nAchR alpha3, alpha5, and ... Read more...

Latest indexed articles for 'Receptors, Cholinergic - Metabolism'

These are the very latest articles for this heading:

• Alterations in cholinergic sensitivity of respiratory neurons induced by pre-natal nicotine: a mechanism for respiratory dysfunction in neonatal mice. 10 Sep 2009
• Boosting cholinergic activity in gustatory cortex enhances the salience of a familiar conditioned stimulus in taste aversion learning. 30 Jul 2009
• Acetylcholine receptor pathway and lung cancer. 30 Jul 2009
• Receptor architecture of human cingulate cortex: evaluation of the four-region neurobiological model. 30 Jul 2009
• Acetylcholine receptor-alpha subunit expression in myasthenia gravis: a role for the autoantigen in pathogenesis? 30 Jul 2009
• Identification of an agrin mutation that causes congenital myasthenia and affects synapse function. 21 Jul 2009
• Myasthenic syndrome due to defects in rapsyn: Clinical and molecular findings in 39 patients. 19 Jul 2009
• The formation of acetylcholine receptor clusters visualized with quantum dots. 14 Jul 2009
• Reflex control of immunity. 30 May 2009
• Myasthenia gravis associated with etanercept therapy. 30 May 2009
• Acetylcholinesterase inhibitors in MG: to be or not to be? 30 May 2009
• Cholinergic control of inflammation. 30 May 2009
• Regulation of acetylcholine receptor clustering by ADF/cofilin-directed vesicular trafficking. 29 May 2009
• Cholinergic responses and intrinsic membrane properties of developing thalamic parafascicular neurons. 25 May 2009
• Energy and structure of the M2 helix in acetylcholine receptor-channel gating. 18 May 2009
• An increase in intracelluar free calcium ions modulated by cholinergic receptors in rat facial nucleus. 3 May 2009
• Cholinesterases and the basal lamina at vertebrate neuromuscular junctions. 3 May 2009
• Duck pancreatic acinar cell as a unique model for independent cholinergic stimulation-secretion coupling. 14 Apr 2009
• 3D-QSAR study of 8-azabicyclo[3.2.1] octane analogs antagonists of cholinergic receptor. 9 Apr 2009
• Redistribution of terbium ions across acetylcholine receptor-enriched membranes induced by agonist desensitization. 6 Apr 2009

See a longer list of these articles.

Technical information about 'Receptors, Cholinergic'

Definition: Cell surface proteins that bind acetylcholine with high affinity and trigger intracellular changes influencing the behavior of cells. Cholinergic receptors are divided into two major classes, muscarinic and nicotinic, based originally on their affinity for nicotine and muscarine. Each group is further subdivided based on pharmacology, location, mode of action, and/or molecular biology.

Registry Number: 0

Descriptor UI: D011950

Alternative terms: Receptors, Cholinergic; Receptors, Acetylcholine; Cholinoceptive Sites; Sites, Cholinoceptive; Receptors, ACh; Cholinergic Receptors; ACh Receptors; Acetylcholine Receptors; Cholinoceptors;

Allowable Qualifiers: administration & dosage; analysis; biosynthesis; blood; classification; deficiency; drug effects; genetics; history; immunology; isolation & purification; metabolism; physiology; radiation effects; therapeutic use; ultrastructure; chemistry;

Tree Number: D12.776.543.750.720.360;

History Note: 74(71)

Technical Notes: /antag = NEUROMUSCULAR BLOCKING AGENTS or NEUROMUSCULAR DEPOLARIZING AGENTS; coord IM with specific cholinergic agent (IM); DF: RECEPT CHOLINERGIC