Receptors, Cholinergic
Research News and Information

Saturday, November 21, 2009

Alterations in cholinergic sensitivity of respiratory neurons induced by pre-natal nicotine: a mechanism for respiratory dysfunction in neonatal mice.

10 Sep 2009 Nicotine may link cigarette smoking during pregnancy with sudden infant death syndrome (SIDS). Pre-natal nicotine leads to diminished ventilatory responses to hypercarbia and reduced central chemoreception in mice at post-natal days 0-3. We studied ... Read more...

Crystal structure of the frizzled-like cysteine-rich domain of the receptor tyrosine kinase MuSK.

2 Aug 2009 Muscle-specific kinase (MuSK) is an essential receptor tyrosine kinase for the establishment and maintenance of the neuromuscular junction (NMJ). Activation of MuSK by agrin, a neuronally derived heparan-sulfate proteoglycan, and LRP4 (low-density ... Read more...

[Molecular bases and therapeutic strategies in defective neuromuscular transmissions: lessons learned from a prototypical synapse]

30 Jul 2009 Neuromuscular junction is a prototypical synapse, and most synaptic molecules expressed in the central nervous system have been first identified at the neuromuscular junction. Congenital myasthenic syndromes are caused by genetic defects of ... Read more...

Latest indexed articles for 'Receptors, Cholinergic'

These are the very latest articles for this heading:

• Alterations in cholinergic sensitivity of respiratory neurons induced by pre-natal nicotine: a mechanism for respiratory dysfunction in neonatal mice. 10 Sep 2009
• Crystal structure of the frizzled-like cysteine-rich domain of the receptor tyrosine kinase MuSK. 2 Aug 2009
• [Molecular bases and therapeutic strategies in defective neuromuscular transmissions: lessons learned from a prototypical synapse] 30 Jul 2009
• Boosting cholinergic activity in gustatory cortex enhances the salience of a familiar conditioned stimulus in taste aversion learning. 30 Jul 2009
• Acetylcholine receptor pathway and lung cancer. 30 Jul 2009
• Receptor architecture of human cingulate cortex: evaluation of the four-region neurobiological model. 30 Jul 2009
• Acetylcholine receptor-alpha subunit expression in myasthenia gravis: a role for the autoantigen in pathogenesis? 30 Jul 2009
• Identification of an agrin mutation that causes congenital myasthenia and affects synapse function. 21 Jul 2009
• Myasthenic syndrome due to defects in rapsyn: Clinical and molecular findings in 39 patients. 19 Jul 2009
• The formation of acetylcholine receptor clusters visualized with quantum dots. 14 Jul 2009
• Seropositive myasthenia gravis: a nationwide epidemiologic study. 12 Jul 2009
• [Anti-MuSK antibody-positive myasthenia gravis with nephrotic syndrome: a case report] 29 Jun 2009
• Muscle-specific tyrosine kinase-antibody-positive myasthenic crisis with detailed electrophysiologic studies. 29 Jun 2009
• Analysis of the mechanism for the development of allergic skin inflammation and the application for its treatment:keratinocytes in atopic dermatitis - their pathogenic involvement. 29 Jun 2009
• Cholinergic receptor signaling modulates spontaneous firing of sinoatrial nodal cells via integrated effects on PKA-dependent Ca(2+) cycling and I(KACh). 17 Jun 2009
• Reflex control of immunity. 30 May 2009
• Involvement of the cholinergic system in the central histamine-induced reversal of critical haemorrhagic hypotension in rats. 30 May 2009
• Myasthenia gravis with presynaptic electrophysiologic abnormalities. 30 May 2009
• Long remission in muscle-specific kinase antibody-positive juvenile myasthenia. 30 May 2009
• Myasthenia gravis associated with etanercept therapy. 30 May 2009

See a longer list of these articles.

Technical information about 'Receptors, Cholinergic'

Definition: Cell surface proteins that bind acetylcholine with high affinity and trigger intracellular changes influencing the behavior of cells. Cholinergic receptors are divided into two major classes, muscarinic and nicotinic, based originally on their affinity for nicotine and muscarine. Each group is further subdivided based on pharmacology, location, mode of action, and/or molecular biology.

Registry Number: 0

Descriptor UI: D011950

Alternative terms: Receptors, Cholinergic; Receptors, Acetylcholine; Cholinoceptive Sites; Sites, Cholinoceptive; Receptors, ACh; Cholinergic Receptors; ACh Receptors; Acetylcholine Receptors; Cholinoceptors;

Allowable Qualifiers: administration & dosage; analysis; biosynthesis; blood; classification; deficiency; drug effects; genetics; history; immunology; isolation & purification; metabolism; physiology; radiation effects; therapeutic use; ultrastructure; chemistry;

Tree Number: D12.776.543.750.720.360;

History Note: 74(71)

Technical Notes: /antag = NEUROMUSCULAR BLOCKING AGENTS or NEUROMUSCULAR DEPOLARIZING AGENTS; coord IM with specific cholinergic agent (IM); DF: RECEPT CHOLINERGIC