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Receptors, Corticotropin-Releasing Hormone
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Definition of 'Receptors, Corticotropin-Releasing Hormone'

Cell surface proteins that bind corticotropin-releasing hormone with high affinity and trigger intracellular changes which influence the behavior of cells. The corticotropin releasing-hormone receptors on anterior pituitary cells mediate the stimulation of corticotropin release by hypothalamic corticotropin releasing factor. The physiological consequence of activating corticotropin-releasing hormone receptors on central neurons is not well understood.

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Sunday, November 22, 2009

Central nesfatin-1 reduces dark-phase food intake and gastric emptying in rats: differential role of corticotropin-releasing factor2 receptor.

29 Sep 2009 Nesfatin-1, derived from nucleobindin2, is expressed in the hypothalamus and reported in one study to reduce food intake (FI) in rats. To characterize the central anorexigenic action of nesfatin-1 and whether gastric emptying (GE) is altered, we ... Read more...


Protective effect of CRHR1 gene variants on the development of adult depression following childhood maltreatment: replication and extension.

30 Aug 2009 CONTEXT: A previous study reported a gene x environment interaction in which a haplotype in the corticotropin-releasing hormone receptor 1 gene (CRHR1) was associated with protection against adult depressive symptoms in individuals who were ... Read more...


Corticotropin-releasing factor receptor antagonism within the dorsal raphe nucleus reduces social anxiety-like behavior after early-life social isolation.

10 Aug 2009 Social isolation of rats during the early part of development increases social anxiety-like behavior in adulthood. Furthermore, early-life social isolation increases the levels of corticotropin-releasing factor (CRF) receptors in the serotonergic ... Read more...

 

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Technical information about 'Receptors, Corticotropin-Releasing Hormone'

Definition: Cell surface proteins that bind corticotropin-releasing hormone with high affinity and trigger intracellular changes which influence the behavior of cells. The corticotropin releasing-hormone receptors on anterior pituitary cells mediate the stimulation of corticotropin release by hypothalamic corticotropin releasing factor. The physiological consequence of activating corticotropin-releasing hormone receptors on central neurons is not well understood.

Registry Number: 0

Descriptor UI: D018019

Alternative terms: Receptors, Corticotropin-Releasing Hormone; Corticotropin-Releasing Hormone Receptors; Hormone Receptors, Corticotropin-Releasing; Receptors, Corticotropin Releasing Hormone; Corticotropin Releasing-Hormone Receptors; Corticotropin Releasing Hormone Receptors; Receptors, Corticotropin Releasing-Hormone; Releasing-Hormone Receptors, Corticotropin; CRF Receptors; Corticotropin Releasing-Factor Receptors; Corticotropin Releasing Factor Receptors; Receptors, Corticotropin Releasing-Factor; Releasing-Factor Receptors, Corticotropin; Receptors, CRF; CRH Receptor; Receptor, CRH; CRH Receptors; Receptors, CRH; Corticotropin Releasing-Hormone Receptor; Corticotropin Releasing Hormone Receptor; Receptor, Corticotropin Releasing-Hormone; Releasing-Hormone Receptor, Corticotropin; CRF Receptor; Receptor, CRF;

Allowable Qualifiers: administration & dosage; analysis; antagonists & inhibitors; biosynthesis; blood; classification; deficiency; drug effects; genetics; history; immunology; isolation & purification; metabolism; physiology; radiation effects; therapeutic use; ultrastructure; chemistry; agonists;

Tree Number: D12.776.543.750.100.180; D12.776.543.750.720.600.290; D12.776.543.750.750.555.290; D12.776.543.750.750.700.150;

Online Note: use RECEPTORS, CORTICOTROPIN-RELEASING HORMONE (NM) to search CORTICOTROPIN RELEASING HORMONE RECEPTOR 1983-93

History Note: 94; was CORTICOTROPIN RELEASING HORMONE RECEPTOR (NM) 1983-93

Technical Notes: DF: note short X ref

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