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Receptors, Dopamine D1
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Definition of 'Receptors, Dopamine D1'

A subfamily of G-PROTEIN-COUPLED RECEPTORS that bind the neurotransmitter DOPAMINE and modulate its effects. D1-class receptor genes lack INTRONS, and the receptors stimulate ADENYLATE CYCLASE.

Common names: Receptors, Dopamine D1; Dopamine-D1 Receptor; Dopamine D1 Receptor; Receptor, Dopamine-D1; Dopamine D1 Receptors; D1 Receptors, Dopamine

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Saturday, November 21, 2009

Time-dependent exposure of nicotine and smoke modulate ultrasubcellular organelle localization of dopamine D1 and D2 receptors in the rat caudate-putamen.

29 Sep 2009 The correlation of the subcellular localization of dopamine D(1) and D(2) receptors (DA D(1) R, DA D(2) R) with nicotine addiction has not been studied. We demonstrated the ultrasubcellular organelle localization of DA D(1) and D(2) Rs in the ... Read more...


Serotonin 1B receptor stimulation reduces D1 receptor agonist-induced dyskinesia.

21 Sep 2009 Dopamine replacement therapy for the treatment of Parkinson's disease leads to deleterious abnormal involuntary movements (AIMs), known as L-3,4-dihydroxyphenylalanine (L-DOPA)-induced dyskinesia, which parallels enhanced striatal dopamine D1 ... Read more...


Exercise activates redox-sensitive transcription factors and restores renal D1 receptor function in old rats.

14 Sep 2009 We have previously reported that age-associated oxidative stress via protein kinase C (PKC) increases D1 receptor (D1R) phosphorylation and causes D1R-G protein uncoupling in renal proximal tubules (RPTs) of old Fischer 344 rats. This results in ... Read more...

 

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Technical information about 'Receptors, Dopamine D1'

Definition: A subfamily of G-PROTEIN-COUPLED RECEPTORS that bind the neurotransmitter DOPAMINE and modulate its effects. D1-class receptor genes lack INTRONS, and the receptors stimulate ADENYLATE CYCLASE.

Registry Number: 0

Descriptor UI: D017447

Alternative terms: Receptors, Dopamine D1; Dopamine-D1 Receptor; Dopamine D1 Receptor; Receptor, Dopamine-D1; Dopamine D1 Receptors; D1 Receptors, Dopamine;

Allowable Qualifiers: administration & dosage; analysis; antagonists & inhibitors; biosynthesis; blood; classification; deficiency; drug effects; genetics; history; immunology; isolation & purification; metabolism; physiology; radiation effects; therapeutic use; ultrastructure; chemistry; agonists;

Tree Number: D12.776.543.750.070.300.400.400; D12.776.543.750.100.150.400.400; D12.776.543.750.720.300.300.400.400;

Online Note: use RECEPTORS, DOPAMINE D1 (NM) to search DOPAMINE-D1 RECEPTOR 1982-92

History Note: 93; was DOPAMINE-D1 RECEPTOR (NM) 1982-92

Technical Notes: DF: RECEPT DOPAMINE D1

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