Receptors, Eph Family
Research News and Information

Sunday, November 22, 2009

A role for C. elegans Eph RTK signaling in PTEN regulation.

29 Sep 2009 PTEN is one of the most commonly lost tumor suppressors in human cancer and is known to inhibit insulin signaling. Eph receptor tyrosine kinases (RTKs) have also been implicated in cancer formation and progression, and they have diverse functions, ... Read more...

Integration of neuronal clones in the radial cortical columns by EphA and ephrin-A signalling.

14 Sep 2009 The cerebral cortex is a laminated sheet of neurons composed of the arrays of intersecting radial columns. During development, excitatory projection neurons originating from the proliferative units at the ventricular surface of the embryonic ... Read more...

Eph/ephrinB mediate dental pulp stem cell mobilization and function.

30 Aug 2009 Damage to the dentin matrix investigates the proliferation and mobilization of dental progenitor cells to the injury site, the mechanisms of which are not defined. EphB receptors and ephrin-B ligands expressed within the perivascular niche of dental ... Read more...

Latest indexed articles for 'Receptors, Eph Family'

These are the very latest articles for this heading:

• EphB maintains dendritic spine morphology through focal adhesion kinase. 19 Oct 2009
• A role for C. elegans Eph RTK signaling in PTEN regulation. 29 Sep 2009
• Integration of neuronal clones in the radial cortical columns by EphA and ephrin-A signalling. 14 Sep 2009
• Eph/ephrinB mediate dental pulp stem cell mobilization and function. 30 Aug 2009
• Control of extracellular matrix assembly along tissue boundaries via Integrin and Eph/Ephrin signaling. 27 Jul 2009
• Expression of ephrinA5 during development and potential involvement in the guidance of the mesostriatal pathway. 30 Jun 2009
• Focal adhesion kinase acts downstream of EphB receptors to maintain mature dendritic spines by regulating cofilin activity. 22 Jun 2009
• Ligand recognition by A-class Eph receptors: crystal structures of the EphA2 ligand-binding domain and the EphA2/ephrin-A1 complex. 10 Jun 2009
• EphrinB reverse signaling contributes to endothelial and mural cell assembly into vascular structures. 29 Apr 2009
• Venous and arterial identity: a role for caveolae? 29 Apr 2009
• Beta-Arrestin2 regulates RANKL and ephrins gene expression in response to bone remodeling in mice. 29 Apr 2009
• Eph/ephrin gradients in the retinotectal system of Rana pipiens: developmental and adult expression patterns. 29 Apr 2009
• EphrinA and TrkB interact to promote axon branching. 6 Apr 2009
• Key roles of Ephs and ephrins in retinotectal topographic map formation. 30 Mar 2009
• Beta2-chimaerin binds to EphA receptors and regulates cell migration. 20 Mar 2009
• Reverse signaling by glycosylphosphatidylinositol-linked Manduca ephrin requires a SRC family kinase to restrict neuronal migration in vivo. 16 Mar 2009
• Organizing the thymus gland. 30 Jan 2009
• [Role of ephrins in regulation of tumour cell migration] 30 Dec 2008
• EphrinA-EphA receptor interactions in mouse spinal neurulation: implications for neural fold fusion. 30 Dec 2008
• Specification of motor axon trajectory by ephrin-B:EphB signaling: symmetrical control of axonal patterning in the developing limb. 24 Dec 2008

See a longer list of these articles.

Technical information about 'Receptors, Eph Family'

Definition: A large family of receptor protein-tyrosine kinases that are structurally-related. The name of this family of proteins derives from original protein Eph (now called the EPHA1 RECEPTOR), which was named after the cell line it was first discovered in: Erythropoietin-Producing human Hepatocellular carcinoma cell line. Members of this family have been implicated in regulation of cell-cell interactions involved in nervous system patterning and development.

Registry Number: EC 2.7.1.112

Descriptor UI: D036081

Alternative terms: Receptors, Eph Family; Eph Family Receptors; Ephrin Receptors; Receptors, Ephrin; Eph Receptor Tyrosine Kinase; Eph Receptors; Receptors, Eph; Ephrin A Receptors; Receptors, Ephrin A; EphA Receptors; Ephrin B Receptors; EphB Receptors; Receptors, EphB; EphB Receptor; Ephrin B Receptor; Receptor, Ephrin B;

Allowable Qualifiers: administration & dosage; analysis; antagonists & inhibitors; biosynthesis; blood; classification; deficiency; drug effects; genetics; history; immunology; isolation & purification; metabolism; physiology; radiation effects; therapeutic use; ultrastructure; chemistry; agonists;

Tree Number: D08.811.913.696.620.682.725.400.850; D12.776.543.750.060.500;

History Note: 2003; use RECEPTORS, EPH FAMILY (NM) 1999-2002, for EPH RECEPTOR TYROSINE KINASE use EPHA1 RECEPTOR (NM) 1999-2002;