Receptors, GABA-B
Research News and Information

Monday, November 23, 2009

N-type calcium channels mediate a GABA(B) presynaptic modulation in the corticostriatal synapse in turtle's paleostriatum augmentatum.

29 Sep 2009 Spikes population evoked by a paired pulse protocol were used to assess the influence of GABA(A) and GABA(B) receptors agonists and antagonists on the synaptic potentials and in the S2/S1 ratio in a paired pulse (PP) protocol in the ... Read more...

GABA(B) receptor activation triggers BDNF release and promotes the maturation of GABAergic synapses.

14 Sep 2009 GABA, the main inhibitory neurotransmitter in the adult brain, has recently emerged as an important signal in network development. Most of the trophic functions of GABA have been attributed to depolarization of the embryonic and neonatal neurons via ... Read more...

Angiotensin II enhances GABA(B) receptor-mediated responses and expression in nucleus tractus solitarii of rats.

9 Sep 2009 Angiotensin II (ANG II) increases GABA(B) receptor expression in neuronal cultures from the nucleus tractus solitarii (NTS). In the present study, the chronic effects of ANG II on GABA(B) receptor expression and activity were examined in the NTS of ... Read more...

Latest indexed articles for 'Receptors, GABA-B'

These are the very latest articles for this heading:

• N-type calcium channels mediate a GABA(B) presynaptic modulation in the corticostriatal synapse in turtle's paleostriatum augmentatum. 29 Sep 2009
• GABA(B) receptor activation triggers BDNF release and promotes the maturation of GABAergic synapses. 14 Sep 2009
• Angiotensin II enhances GABA(B) receptor-mediated responses and expression in nucleus tractus solitarii of rats. 9 Sep 2009
• Arrested maturation of excitatory synapses in autosomal dominant lateral temporal lobe epilepsy. 21 Aug 2009
• Spatial profile and differential recruitment of GABAB modulate oscillatory activity in auditory cortex. 17 Aug 2009
• GABA release from cerebellar stellate cells is developmentally regulated by presynaptic GABA(B) receptors in a target-cell-specific manner. 5 Aug 2009
• Genome-wide association study reveals multiple nasopharyngeal carcinoma-associated loci within the HLA region at chromosome 6p21.3. 4 Aug 2009
• The rat prelimbic cortex mediates inhibitory response control but not the consolidation of instrumental learning. 30 Jul 2009
• GABA(B) receptors, schizophrenia and sleep dysfunction: a review of the relationship and its potential clinical and therapeutic implications. 30 Jul 2009
• Hippocampal synapsin isoform levels are linked to spatial memory enhancement by SGS742. 30 Jul 2009
• GABA(B) receptor activation inhibits neuronal excitability and spatial learning in the entorhinal cortex by activating TREK-2 K+ channels. 28 Jul 2009
• GABA and cortical inhibition in motor and non-motor regions using combined TMS-EEG: a time analysis. 23 Jul 2009
• G-protein-coupled-receptor-mediated presynaptic inhibition in the cerebellum. 22 Jul 2009
• Role for GABA agonists in the nucleus accumbens in regulating morphine self-administration. 8 Jul 2009
• Narcolepsy: action of two gamma-aminobutyric acid type B agonists, baclofen and sodium oxybate. 29 Jun 2009
• Behavioral effects of gamma-hydroxybutyrate, its precursor gamma-butyrolactone, and GABA(B) receptor agonists: time course and differential antagonism by the GABA(B) receptor antagonist 3-aminopropyl(diethoxymethyl)phosphinic acid (CGP35348). 27 Jun 2009
• Subcellular compartment-specific molecular diversity of pre- and post-synaptic GABA-activated GIRK channels in Purkinje cells. 20 Jun 2009
• Distinct roles of GABA(A) and GABA(B) receptors in balancing and terminating persistent cortical activity. 8 Jun 2009
• The tuberal lateral hypothalamus is a major target for GABAA--but not GABAB-mediated control of food intake. 4 Jun 2009
• Site-specific microinjection of baclofen into the anterior ventral tegmental area reduces binge-like ethanol intake in male C57BL/6J mice. 30 May 2009

See a longer list of these articles.

Technical information about 'Receptors, GABA-B'

Definition: Cell surface proteins which bind GAMMA-AMINOBUTYRIC ACID and influence cells via interactions with G-proteins. GABA-B receptors are pharmacologically characterized by their insensitivity to the blocker bicuculline and sensitivity to the agonist L-baclofen. They are found both presynaptically and postsynaptically, and act variously by inhibition of adenylate cyclase, activation of phospholipase A2, activation of potassium channels, and inactivation of voltage-activated calcium channels.

Registry Number: 0

Descriptor UI: D018080

Alternative terms: Receptors, GABA-B; Receptors, GABA B; GABA-B Receptor; GABA B Receptor; Receptor, GABA-B; Receptors, Baclofen; Baclofen Receptor; Receptor, Baclofen; Baclofen Receptors; GABA-B Receptors; GABA B Receptors;

Allowable Qualifiers: administration & dosage; analysis; antagonists & inhibitors; biosynthesis; blood; classification; deficiency; drug effects; genetics; history; immunology; isolation & purification; metabolism; physiology; radiation effects; therapeutic use; ultrastructure; chemistry; agonists;

Tree Number: D12.776.543.750.100.300; D12.776.543.750.720.200.300.320;

Online Note: use RECEPTORS, GABA-B (NM) to search BACLOFEN RECEPTORS 1985-93

History Note: 94; BACLOFEN RECEPTORS was BACLOFEN RECEPTOR (NM) 1985-93

Technical Notes: DF: RECEPT GABA B