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Receptors, Glucocorticoid
Research News and Information
Definition of 'Receptors, Glucocorticoid'Cytoplasmic proteins that specifically bind glucocorticoids and mediate their cellular effects. The glucocorticoid receptor-glucocorticoid complex acts in the nucleus to induce transcription of DNA. Glucocorticoids were named for their actions on blood glucose concentration, but they have equally important effects on protein and fat metabolism. Cortisol is the most important example. Common names: Receptors, Glucocorticoid; Glucocorticoid Receptors; Glucocorticoid Receptor; Receptor, Glucocorticoid; Receptors, Glucocorticoids; Glucocorticoids Receptors; Receptors, Corticoid Type II; Corticoid Type II Receptors; Corticoid II Receptor; Receptor, Corticoid II; Receptors, Corticoid II |
Sunday, November 22, 2009
An epistatic ratchet constrains the direction of glucocorticoid receptor evolution.
22 Sep 2009 
The extent to which evolution is reversible has long fascinated biologists. Most previous work on the reversibility of morphological and life-history evolution has been indecisive, because of uncertainty and bias in the methods used to infer ... Read more...
Enhancement of ligand-dependent down-regulation of glucocorticoid receptor by lipopolysaccharide.
31 Aug 2009 AIMS: The inhibitory actions of glucocorticoids are often attenuated in inflamed tissues. The aim of the present study was to investigate whether the dexamethasone-induced downregulation of glucocorticoid receptor (GR) expression was enhanced by the ... Read more...
Hop bitter acids efficiently block inflammation independent of GRalpha, PPARalpha, or PPARgamma.
30 Aug 2009 Hop (Humulus lupulus L.) is an essential ingredient of beer, where it provides the typical bitter taste, but is also applied in traditional folk medicine for sedative and antibacterial purposes. In this study, we demonstrate and compare the ... Read more...
Latest indexed articles for 'Receptors, Glucocorticoid'
These are the very latest articles for this heading:
- An epistatic ratchet constrains the direction of glucocorticoid receptor evolution. 22 Sep 2009
- Enhancement of ligand-dependent down-regulation of glucocorticoid receptor by lipopolysaccharide. 31 Aug 2009
- Hop bitter acids efficiently block inflammation independent of GRalpha, PPARalpha, or PPARgamma. 30 Aug 2009
- Corticosterone reduces dendritic complexity in developing hippocampal CA1 neurons. 30 Aug 2009
- Vulnerability to depression: what is the role of stress genes in gene x environment interaction? 30 Aug 2009
- Modulation of presynaptic glucocorticoid receptors on glutamate release from rat hippocampal nerve terminals. 30 Aug 2009
- Steroid hormone pulsing drives cyclic gene expression. 30 Aug 2009
- Stable silencing of the glucocorticoid receptor in myelin-specific T effector cells by retroviral delivery of shRNA: insight into neuroinflammatory disease. 30 Aug 2009
- Glucocorticoid production and regulation in thymus: of mice and birds.
30 Aug 2009 - Interaction of mitochondrial thioredoxin with glucocorticoid receptor and NF-kappaB modulates glucocorticoid receptor and NF-kappaB signalling in HEK-293 cells. 25 Aug 2009
- FoxA1 binding directs chromatin structure and the functional response of a glucocorticoid receptor-regulated promoter. 15 Aug 2009
- Ultradian hormone stimulation induces glucocorticoid receptor-mediated pulses of gene transcription. 14 Aug 2009
- Investigation of the relative cellular permeability of DNA-binding pyrrole-imidazole polyamides. 11 Aug 2009
- Compound A, a plant origin ligand of glucocorticoid receptors, increases regulatory T cells and M2 macrophages to attenuate experimental autoimmune neuritis with reduced side effects. 10 Aug 2009
- Overcoming steroid unresponsiveness in airways disease. 30 Jul 2009
- Activity of the 5-HT1A receptor is involved in the alteration of glucocorticoid receptor in hippocampus and corticotropin-releasing factor in hypothalamus in SPS rats. 30 Jul 2009
- Novel human pathological mutations. Gene symbol: NR3C1. Disease: glucocorticoid receptor deficiency. 30 Jul 2009
- Ursolic acid triggers apoptosis and Bcl-2 downregulation in MCF-7 breast cancer cells. 30 Jul 2009
- Transcriptional activation of an anti-oxidant mouse Pon2 gene by dexamethasone. 29 Jul 2009
- Acute stress enhances glutamatergic transmission in prefrontal cortex and facilitates working memory. 27 Jul 2009
See a longer list of these articles.
Technical information about 'Receptors, Glucocorticoid'
Definition: Cytoplasmic proteins that specifically bind glucocorticoids and mediate their cellular effects. The glucocorticoid receptor-glucocorticoid complex acts in the nucleus to induce transcription of DNA. Glucocorticoids were named for their actions on blood glucose concentration, but they have equally important effects on protein and fat metabolism. Cortisol is the most important example.
Registry Number: 0
Descriptor UI: D011965
Alternative terms: Receptors, Glucocorticoid; Glucocorticoid Receptors; Glucocorticoid Receptor; Receptor, Glucocorticoid; Receptors, Glucocorticoids; Glucocorticoids Receptors; Receptors, Corticoid Type II; Corticoid Type II Receptors; Corticoid II Receptor; Receptor, Corticoid II; Receptors, Corticoid II; Corticoid II Receptors;
Allowable Qualifiers: administration & dosage; analysis; antagonists & inhibitors; biosynthesis; blood; classification; deficiency; drug effects; genetics; history; immunology; isolation & purification; metabolism; physiology; radiation effects; therapeutic use; ultrastructure; chemistry; agonists;
Tree Number: D12.776.826.750.430; D12.776.930.682.430;
History Note: 86(77); was see under RECEPTORS, STEROID 1977-85
Technical Notes: coord IM with specific glucocorticoid (IM); DF: RECEPT GLUCOCORTICOID