Receptors, IgE - Metabolism
Research News and Information

Tuesday, November 24, 2009

Mechanisms of mast cell signaling in anaphylaxis.

29 Sep 2009 The recent development of a consensus definition and proposed diagnostic criteria for anaphylaxis offers promise for research efforts and a better understanding of the epidemiology and pathogenesis of this enigmatic and life-threatening disease. ... Read more...

Phospholipase d promotes lipid microdomain-associated signaling events in mast cells.

28 Sep 2009 Initial IgE-dependent signaling events are associated with detergent-resistant membrane microdomains. Following Ag stimulation, the IgE-receptor (Fc(epsilon)RI ) accumulates within these domains. This facilitates the phosphorylation of Fc(epsilon)RI ... Read more...

SH2 domain-containing phosphatase-2 protein-tyrosine phosphatase promotes Fc(epsilon)RI-induced activation of Fyn and Erk pathways leading to TNF(alpha) release from bone marrow-derived mast cells.

26 Sep 2009 Clustering of the high affinity IgE receptor (Fc(epsilon)RI) in mast cells leads to degranulation and production of numerous cytokines and lipid mediators that promote allergic inflammation. Initiation of FFc(epsilon)RI signaling involves rapid ... Read more...

Latest indexed articles for 'Receptors, IgE - Metabolism'

These are the very latest articles for this heading:

• Mechanisms of mast cell signaling in anaphylaxis. 29 Sep 2009
• Phospholipase d promotes lipid microdomain-associated signaling events in mast cells. 28 Sep 2009
• SH2 domain-containing phosphatase-2 protein-tyrosine phosphatase promotes Fc(epsilon)RI-induced activation of Fyn and Erk pathways leading to TNF(alpha) release from bone marrow-derived mast cells. 26 Sep 2009
• Diffusion and signaling revisited. 16 Sep 2009
• Molecular hydrogen suppresses FcepsilonRI-mediated signal transduction and prevents degranulation of mast cells. 15 Sep 2009
• Small, mobile FcepsilonRI receptor aggregates are signaling competent. 8 Sep 2009
• Mast cell modulation of the immune response. 30 Aug 2009
• IgE-binding properties and selectivity of peptide mimics of the FcvarepsilonRI binding site. 19 Aug 2009
• The basophil activation test in immediate-type drug allergy. 30 Jul 2009
• TLR4-mediated signaling induces MMP9-dependent cleavage of B cell surface CD23. 25 Jul 2009
• FcepsilonRI-mediated mast cell migration: signaling pathways and dependence on cytosolic free Ca2+ concentration. 22 Jul 2009
• SDF-1 and PDGF enhance alphavbeta5-mediated ERK activation and adhesion-independent growth of human pre-B cell lines. 14 Jul 2009
• IgE receptor-mediated alteration of membrane-cytoskeleton interactions revealed by mass spectrometric analysis of detergent-resistant membranes. 12 Jul 2009
• CCR1 expression and signal transduction by murine BMMC results in secretion of TNF-alpha, TGFbeta-1 and IL-6. 8 Jul 2009
• Proinflammatory and Th2 cytokines regulate the high affinity IgE receptor (FcepsilonRI) and IgE-dependant activation of human airway smooth muscle cells. 5 Jul 2009
• Pathogenesis of atopic dermatitis: new developments. 29 Jun 2009
• Basophil responsiveness in chronic urticaria. 29 Jun 2009
• Sphingosine kinase 1 is pivotal for Fc epsilon RI-mediated mast cell signaling and functional responses in vitro and in vivo. 29 Jun 2009
• The beta- and gamma-isoforms of type I PIP5K regulate distinct stages of Ca2+ signaling in mast cells. 21 Jun 2009
• Suppression of IgE B cells and IgE binding to Fc(epsilon)RI by gene therapy with single-chain anti-IgE. 13 Jun 2009

See a longer list of these articles.

Technical information about 'Receptors, IgE'

Definition: Specific molecular sites on the surface of B- and T-lymphocytes which combine with IgEs. Two subclasses exist: low affinity receptors (Fc epsilon RII) and high affinity receptors (Fc epsilon RI).

Registry Number: 0

Descriptor UI: D017455

Alternative terms: Receptors, IgE; CD23 Antigen; Antigen, CD23; Antigens, CD23; CD23 Antigens; IgE Receptors; Immunoglobulin E Receptor; Receptor, Immunoglobulin E; Fc Receptors, epsilon; Receptors, epsilon Fc; epsilon Fc Receptors; Fc epsilon Receptors; epsilon Receptors, Fc; Receptors, Fc epsilon; CD 23 Antigens; Antigens, CD 23; Fc epsilon RII; epsilon RII, Fc; Fc epsilon RI; epsilon RI, Fc;

Allowable Qualifiers: administration & dosage; analysis; antagonists & inhibitors; biosynthesis; blood; classification; deficiency; drug effects; genetics; history; immunology; isolation & purification; metabolism; physiology; radiation effects; therapeutic use; ultrastructure; chemistry; agonists;

Tree Number: D12.776.543.750.705.871.280; D23.050.301.264.035.690; D23.101.100.110.690;

Online Note: use RECEPTORS, IGE (NM) to search IMMUNOGLOBULIN E RECEPTOR 1981-92

History Note: 93; was IMMUNOGLOBULIN E RECEPTOR (NM) 1981-92

Technical Notes: DF: RECEPT IGE