Receptors, Neurokinin-2 - Physiology
Research News and Information

Friday, March 19, 2010

Further investigation into the mechanism of tachykinin NK(2) receptor-triggered serotonin release from guinea-pig proximal colon.

6 May 2009 The effects of the monoamine oxidase A (MAO-A) inhibitor clorgyline, the L-type calcium-channel blocker nicardipine, the syntaxin inhibitor botulinum toxin type C, and the potent thiol-oxidant phenylarsine oxide (PAO) on the selective tachykinin ... Read more...

Neurokinin receptors in recurrent airway obstruction: a comparative study of affected and unaffected horses.

30 Dec 2008 The purpose of the study was to compare in vitro airway responses to neurokinin A & B (NKA and NKB) and expression of NK-2 receptors in airways of horses affected and unaffected with recurrent airway obstruction (RAO). Neurokinin-A, an inflammatory ... Read more...

Involvement of the neurokinin-2 receptor in airway smooth muscle stretch-activated contractions assessed in perfused intact bovine bronchial segments.

19 Aug 2008 The airway response to deep inspirations (DIs) in asthmatics has been shown to be ineffective in producing bronchodilation and can even cause bronchoconstriction. However, the manner by which a DI is able to cause bronchoconstriction remains ... Read more...

Latest indexed articles for 'Receptors, Neurokinin-2 - Physiology'

These are the very latest articles for this heading:

• Further investigation into the mechanism of tachykinin NK(2) receptor-triggered serotonin release from guinea-pig proximal colon. 6 May 2009
• Neurokinin receptors in recurrent airway obstruction: a comparative study of affected and unaffected horses. 30 Dec 2008
• Involvement of the neurokinin-2 receptor in airway smooth muscle stretch-activated contractions assessed in perfused intact bovine bronchial segments. 19 Aug 2008
• Effects of ischemia on tachykinin-containing nerves and neurokinin receptors in the rabbit bladder. 5 Mar 2008
• Expression and coupling of neurokinin receptor subtypes to inositol phosphate and calcium signaling pathways in human airway smooth muscle cells. 16 Jan 2008
• Role of tachykinin NK(1) and NK(2) receptors in colonic sensitivity and stress-induced defecation in gerbils. 13 Dec 2007
• Effect of melatonin on the vasopressin secretion as influenced by tachykinin NK-1 receptor agonist and antagonist: in vivo and in vitro studies. 29 Nov 2007
• Intrathecal high-dose histamine induces spinally-mediated nociceptive behavioral responses through a polyamine site of NMDA receptors. 21 Nov 2007
• Tachykinin NK2 receptor and functional mechanisms in human colon: changes with indomethacin and in diverticular disease and ulcerative colitis. 22 Oct 2007
• Neurokinin receptors modulate the impact of uncontrollable stimulation on adaptive spinal plasticity. 29 Sep 2007
• Role for NK(1) and NK(2) receptors in the motor activity in mouse colon. 3 Jun 2007
• Intraluminal acid induces oesophageal shortening via capsaicin-sensitive neurokinin neurons. 22 May 2007
• Cannabinoid 1 (CB1) receptors coupled to cholinergic motorneurones inhibit neurogenic circular muscle contractility in the human colon. 29 Apr 2006
• Selective blockade of NK2 or NK3 receptors produces anxiolytic- and antidepressant-like effects in gerbils. 17 Apr 2006
• NK2 receptor-mediated spontaneous phasic contractions in normal and ulcerative colitis human sigmoid colon. 20 Mar 2006
• Role of NK1 and NK2 receptors in mouse gastric mechanical activity. 30 Jan 2006
• Functional characterisation of tachykinin receptors in the circular muscle layer of the mouse ileum. 13 Sep 2005
• Neurokinin receptors: relevance to the emerging immune system. 30 Aug 2004
• Neurokinin-1 receptor mediates stress-exacerbated allergic airway inflammation and airway hyperresponsiveness in mice. 29 Jun 2004
• Tachykinins regulate the function of platelets. 4 May 2004

See a longer list of these articles.

Technical information about 'Receptors, Neurokinin-2'

Definition: A class of cell surface receptors for tachykinins that prefers neurokinin A; (NKA, substance K, neurokinin alpha, neuromedin L), neuropeptide K; (NPK); or neuropeptide gamma over other tachykinins. Neurokinin-2 (NK-2) receptors have been cloned and are similar to other G-protein coupled receptors.

Registry Number: 0

Descriptor UI: D018041

Alternative terms: Receptors, Neurokinin-2; Receptors, Neurokinin 2; Neurokinin-2 Receptor; Neurokinin 2 Receptor; Receptor, Neurokinin-2; Neurokinin-2 Receptors; Neurokinin 2 Receptors; NK-2 Receptor; NK 2 Receptor; Receptor, NK-2; NK-2 Receptor Site; NK 2 Receptor Site; Receptor Site, NK-2; Substance K Receptors; Receptors, NK-2; Receptors, NK 2; Receptors, Substance K; SP-K Receptor; Receptor, SP-K; SP K Receptor; SP-K Receptors; Receptors, SP-K; SP K Receptors; Substance K Receptor; Receptor, Substance K; Neurokinin A Receptors; A Receptors, Neurokinin; Receptors, Neurokinin A; NK-2 Receptors; NK 2 Receptors;

Allowable Qualifiers: administration & dosage; analysis; antagonists & inhibitors; biosynthesis; blood; classification; deficiency; drug effects; genetics; history; immunology; isolation & purification; metabolism; physiology; radiation effects; therapeutic use; ultrastructure; chemistry; agonists;

Tree Number: D12.776.543.750.720.600.830.540; D12.776.543.750.750.555.830.540;

Online Note: use RECEPTORS, NEUROKININ-2 (NM) to search SUBSTANCE K RECEPTOR 1984-93

History Note: 94; was SUBSTANCE K RECEPTOR (NM) 1984-93; NK-2 RECEPTOR SITE was SY to TACHYKININ RECEPTOR 1989-93

Technical Notes: tachykinin receptors; DF: RECEPT NEUROKININ 2