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Receptors, Opioid - Drug effects
Research News and Information
Definition of 'Receptors, Opioid'Cell membrane proteins that bind opioids and trigger intracellular changes which influence the behavior of cells. The endogenous ligands for opioid receptors in mammals include three families of peptides, the enkephalins, endorphins, and dynorphins. The receptor classes include mu, delta, and kappa receptors. Sigma receptors bind several psychoactive substances, including certain opioids, but their endogenous ligands are not known. |
Sunday, November 22, 2009
Aug 2009
rIPC (remote ischaemic preconditioning) is a phenomenon whereby short periods of ischaemia and reperfusion of a tissue or organ (e.g. mesentery, kidney) can protect a distant tissue or organ (e.g. heart) against subsequent, potentially lethal, ... Read more...
30 Jul 2009
BACKGROUND: In comparison with cutaneous pain, the role of alpha(2)-adrenoceptor (alpha(2)-AR) agonists in visceral pain has not been extensively examined. We aimed to characterize the antinociceptive effect of IV dexmedetomidine on visceral pain in ... Read more...
9 Jun 2009
AIMS: It has been well documented that ventrolateral periaqueductal gray (vlPAG) matter is a crucial component of the descending pain modulatory system in the chronic pain condition. The aim of the present study was to identify the role of the vlPAG ... Read more...
Latest indexed articles for 'Receptors, Opioid - Drug effects'
These are the very latest articles for this heading:
- Transient limb ischaemia remotely preconditions through a humoral mechanism acting directly on the myocardium: evidence suggesting cross-species protection.
Aug 2009 - The antinociceptive effects of intravenous dexmedetomidine in colorectal distension-induced visceral pain in rats: the role of opioid receptors.
30 Jul 2009 - Involvement of the Nociceptin/Orphanin FQ-NOP receptor system in the ventrolateral periaqueductal gray following mechanical allodynia in chronic pain.
9 Jun 2009 - Sustained morphine treatment augments capsaicin-evoked calcitonin gene-related peptide release from primary sensory neurons in a protein kinase A- and Raf-1-dependent manner.
31 May 2009 - [Comparison of the peripheral and central effects of opiates after iliac crest transplants. Reconstruction of severely atrophied maxilla]
30 May 2009 - Mechanisms underlying morphine analgesic tolerance and dependence.
30 May 2009 - Morphine-6beta-glucuronide rapidly increases pain sensitivity independently of opioid receptor activity in mice and humans.
30 May 2009 - Selective and high affinity labeling of neuronal and recombinant nociceptin receptors with the hexapeptide radioprobe [(3)H]Ac-RYYRIK-ol.
2 May 2009 - Antinociceptive and anti-inflammatory effects of the ethanol extract of Alpinia conchigera Griff. leaves in various animal models.
29 Apr 2009 - Identification of an additional supraspinal component to the analgesic mechanism of action of buprenorphine.
28 Apr 2009 - Opioid-free balanced anesthesia for cervical ganglionectomy subsequent to recent ultra rapid opioid detoxification.
20 Apr 2009 - Nausea and vomiting side effects with opioid analgesics during treatment of chronic pain: mechanisms, implications, and management options.
17 Mar 2009 - Neuropeptide VF-associated satiety involves mu and kappa but not delta subtypes of opioid receptors in chicks.
12 Mar 2009 - The effect of naltrexone on amphetamine-induced conditioned place preference and locomotor behaviour in the rat.
3 Mar 2009 - Potency of naltrexone to reduce ethanol self-administration in rats is greater for subcutaneous versus intraperitoneal injection.
27 Feb 2009 - Breakthrough pain: on the road again.
9 Feb 2009 - Targeting fatty acid amide hydrolase (FAAH) to treat pain and inflammation.
27 Jan 2009 - Opioids and sensory nerves.
30 Dec 2008 - Pain treatment with opioids : achieving the minimal effective and the minimal interacting dose.
30 Dec 2008 - Opiates as antidepressants.
30 Dec 2008
See a longer list of these articles.
Technical information about 'Receptors, Opioid'
Definition: Cell membrane proteins that bind opioids and trigger intracellular changes which influence the behavior of cells. The endogenous ligands for opioid receptors in mammals include three families of peptides, the enkephalins, endorphins, and dynorphins. The receptor classes include mu, delta, and kappa receptors. Sigma receptors bind several psychoactive substances, including certain opioids, but their endogenous ligands are not known.
Registry Number: 0
Descriptor UI: D011957
Alternative terms: Receptors, Opioid; Opiate Receptors; Opioid Receptor; Receptor, Opioid; Opioid Receptors; Opiate Receptor; Receptor, Opiate; Receptors, Opiate; Receptors, Normorphine; Normorphine Receptors; Receptors, Narcotic; Narcotic Receptors; Enkephalin Receptor; Receptor, Enkephalin; Receptors, Enkephalin; Enkephalin Receptors; beta-Endorphin Receptor; Receptor, beta-Endorphin; beta Endorphin Receptor; Receptors, beta-Endorphin; Receptors, beta Endorphin; beta-Endorphin Receptors; Receptors, Endorphin; Endorphin Receptor; Receptor, Endorphin; Endorphin Receptors;
Allowable Qualifiers: administration & dosage; analysis; antagonists & inhibitors; biosynthesis; blood; classification; deficiency; drug effects; genetics; history; immunology; isolation & purification; metabolism; physiology; radiation effects; therapeutic use; ultrastructure; chemistry; agonists;
Tree Number: D12.776.543.750.100.620; D12.776.543.750.720.600.610; D12.776.543.750.750.555.610;
Online Note: use RECEPTORS, OPIOID to search RECEPTORS, ENDORPHIN 1980-93 & RECEPTORS, NARCOTIC 1977-79
History Note: 94; was RECEPTORS, ENDORPHIN 1980-93; was RECEPTORS, NARCOTIC 1977-79
Technical Notes: coord IM with specific opioid (IM); DF: RECEPT OPIOID