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Receptors, Opioid - Drug effects
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Definition of 'Receptors, Opioid'

Cell membrane proteins that bind opioids and trigger intracellular changes which influence the behavior of cells. The endogenous ligands for opioid receptors in mammals include three families of peptides, the enkephalins, endorphins, and dynorphins. The receptor classes include mu, delta, and kappa receptors. Sigma receptors bind several psychoactive substances, including certain opioids, but their endogenous ligands are not known.

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Sunday, November 22, 2009

Transient limb ischaemia remotely preconditions through a humoral mechanism acting directly on the myocardium: evidence suggesting cross-species protection.

Aug 2009 rIPC (remote ischaemic preconditioning) is a phenomenon whereby short periods of ischaemia and reperfusion of a tissue or organ (e.g. mesentery, kidney) can protect a distant tissue or organ (e.g. heart) against subsequent, potentially lethal, ... Read more...


The antinociceptive effects of intravenous dexmedetomidine in colorectal distension-induced visceral pain in rats: the role of opioid receptors.

30 Jul 2009 BACKGROUND: In comparison with cutaneous pain, the role of alpha(2)-adrenoceptor (alpha(2)-AR) agonists in visceral pain has not been extensively examined. We aimed to characterize the antinociceptive effect of IV dexmedetomidine on visceral pain in ... Read more...


Involvement of the Nociceptin/Orphanin FQ-NOP receptor system in the ventrolateral periaqueductal gray following mechanical allodynia in chronic pain.

9 Jun 2009 AIMS: It has been well documented that ventrolateral periaqueductal gray (vlPAG) matter is a crucial component of the descending pain modulatory system in the chronic pain condition. The aim of the present study was to identify the role of the vlPAG ... Read more...

 

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Technical information about 'Receptors, Opioid'

Definition: Cell membrane proteins that bind opioids and trigger intracellular changes which influence the behavior of cells. The endogenous ligands for opioid receptors in mammals include three families of peptides, the enkephalins, endorphins, and dynorphins. The receptor classes include mu, delta, and kappa receptors. Sigma receptors bind several psychoactive substances, including certain opioids, but their endogenous ligands are not known.

Registry Number: 0

Descriptor UI: D011957

Alternative terms: Receptors, Opioid; Opiate Receptors; Opioid Receptor; Receptor, Opioid; Opioid Receptors; Opiate Receptor; Receptor, Opiate; Receptors, Opiate; Receptors, Normorphine; Normorphine Receptors; Receptors, Narcotic; Narcotic Receptors; Enkephalin Receptor; Receptor, Enkephalin; Receptors, Enkephalin; Enkephalin Receptors; beta-Endorphin Receptor; Receptor, beta-Endorphin; beta Endorphin Receptor; Receptors, beta-Endorphin; Receptors, beta Endorphin; beta-Endorphin Receptors; Receptors, Endorphin; Endorphin Receptor; Receptor, Endorphin; Endorphin Receptors;

Allowable Qualifiers: administration & dosage; analysis; antagonists & inhibitors; biosynthesis; blood; classification; deficiency; drug effects; genetics; history; immunology; isolation & purification; metabolism; physiology; radiation effects; therapeutic use; ultrastructure; chemistry; agonists;

Tree Number: D12.776.543.750.100.620; D12.776.543.750.720.600.610; D12.776.543.750.750.555.610;

Online Note: use RECEPTORS, OPIOID to search RECEPTORS, ENDORPHIN 1980-93 & RECEPTORS, NARCOTIC 1977-79

History Note: 94; was RECEPTORS, ENDORPHIN 1980-93; was RECEPTORS, NARCOTIC 1977-79

Technical Notes: coord IM with specific opioid (IM); DF: RECEPT OPIOID

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