Receptors, Opioid, delta - Drug effects
Research News and Information

Sunday, November 22, 2009

Morphine-6beta-glucuronide rapidly increases pain sensitivity independently of opioid receptor activity in mice and humans.

30 May 2009 BACKGROUND: Previous data indicate that morphine-6beta-glucuronide (M6G), a morphine metabolite with analgesic properties, can paradoxically increase pain sensitivity in mice and humans. The authors tested mice and humans for M6G hyperalgesia and ... Read more...

Neuropeptide VF-associated satiety involves mu and kappa but not delta subtypes of opioid receptors in chicks.

12 Mar 2009 Neuropeptide VF (NPVF) induces satiety through hypothalamic interactions; however, the central mechanism that mediates these effects is poorly understood. Therefore, this study was conducted to explore some possible opioid receptor associated ... Read more...

Role of mu- and delta-opioid receptors in the nucleus accumbens in cocaine-seeking behavior.

9 Mar 2009 Earlier studies suggest that opioid receptors in the ventral tegmental area, but not the nucleus accumbens (NAc), play a role in relapse to drug-seeking behavior. However, environmental stimuli that elicit relapse also release the endogenous opioid ... Read more...

Latest indexed articles for 'Receptors, Opioid, delta - Drug effects'

These are the very latest articles for this heading:

• Morphine-6beta-glucuronide rapidly increases pain sensitivity independently of opioid receptor activity in mice and humans. 30 May 2009
• Neuropeptide VF-associated satiety involves mu and kappa but not delta subtypes of opioid receptors in chicks. 12 Mar 2009
• Role of mu- and delta-opioid receptors in the nucleus accumbens in cocaine-seeking behavior. 9 Mar 2009
• Na+ mechanism of delta-opioid receptor induced protection from anoxic K+ leakage in the cortex. 27 Feb 2009
• Hypertensive state, independent of hypertrophy, exhibits an attenuated decrease in systolic function on cardiac kappa-opioid receptor stimulation. 28 Jan 2009
• Rewarding morphine-induced synaptic function of delta-opioid receptors on central glutamate synapses. 21 Jan 2009
• Pharmacological characterization of ATPM [(-)-3-aminothiazolo[5,4-b]-N-cyclopropylmethylmorphinan hydrochloride], a novel mixed kappa-agonist and mu-agonist/-antagonist that attenuates morphine antinociceptive tolerance and heroin self-administration behavior. 7 Jan 2009
• Targeting endogenous mu- and delta-opioid receptor systems for the treatment of drug addiction. 30 Oct 2008
• delta-Opioid receptor antagonism induces NMDA receptor-dependent excitotoxicity in anoxic turtle cortex. 30 Oct 2008
• In vivo trafficking of endogenous opioid receptors. 3 Oct 2008
• Evidence for a mu-delta opioid receptor complex in CHO cells co-expressing mu and delta opioid peptide receptors. 6 Apr 2008
• Opioid pharmacology. 28 Feb 2008
• Toward a structure-based model of salvinorin A recognition of the kappa-opioid receptor. 21 Feb 2008
• Acute and chronic heroin dependence in mice: contribution of opioid and excitatory amino acid receptors. 17 Feb 2008
• Mito-controversies: mitochondrial permeability transition pore and myocardial reperfusion injury. 30 Jan 2008
• Co-expression of mu and delta opioid receptors as receptor-G protein fusions enhances both mu and delta signalling via distinct mechanisms. 5 Jan 2008
• Alkaloids with human delta-opioid receptor binding affinity from the Australian rainforest tree Peripentadenia mearsii. 25 Nov 2007
• Modulation of extracellular signal-regulated kinase (ERK) by opioid and cannabinoid receptors that are expressed in the same cell. 2 Nov 2007
• Dependence of the analgesic activities of dermorphin, metenkephalin, and dynorphin A on the ambient temperature. 30 Oct 2007
• New benzomorphan derivatives of MPCB as MOP and KOP receptor ligands. 30 Oct 2007

See a longer list of these articles.

Technical information about 'Receptors, Opioid, delta'

Definition: A class of opioid receptors recognized by its pharmacological profile. Delta opioid receptors bind endorphins and enkephalins with approximately equal affinity and have less affinity for dynorphins.

Registry Number: 0

Descriptor UI: D017465

Alternative terms: Receptors, Opioid, delta; Opioid Receptors, delta; delta Opioid Receptors; Receptors, delta Opioid; Receptors, delta; delta Receptor; Receptor, delta; delta Receptors; delta Opioid Receptor; Opioid Receptor, delta; Receptor, delta Opioid;

Allowable Qualifiers: administration & dosage; analysis; antagonists & inhibitors; biosynthesis; blood; classification; deficiency; drug effects; genetics; history; immunology; isolation & purification; metabolism; physiology; radiation effects; therapeutic use; ultrastructure; chemistry; agonists;

Tree Number: D12.776.543.750.100.620.200; D12.776.543.750.720.600.610.200; D12.776.543.750.750.555.610.200;

Online Note: use RECEPTORS, OPIOID, DELTA to search RECEPTORS, DELTA 1993; use RECEPTORS, OPIOID, DELTA (NM) to search DELTA RECEPTOR 1982-92

History Note: 94; was RECEPTORS, DELTA 1993; was DELTA RECEPTOR (NM) 1982-92

Technical Notes: opioid receptors; DF: RECEPT DELTA