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Receptors, Presynaptic
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Definition of 'Receptors, Presynaptic'

Neurotransmitter receptors located on or near presynaptic terminals or varicosities. Presynaptic receptors which bind transmitter molecules released by the terminal itself are termed AUTORECEPTORS.

Common names: Receptors, Presynaptic; Presynaptic Receptors; Presynaptic Receptor; Receptor, Presynaptic

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Sunday, November 22, 2009

Brain-derived neurotrophic factor controls activity-dependent maturation of CA1 synapses by downregulating tonic activation of presynaptic kainate receptors.

7 Sep 2009 Immature hippocampal synapses express presynaptic kainate receptors (KARs), which tonically inhibit glutamate release. Presynaptic maturation involves activity-dependent downregulation of the tonic KAR activity and consequent increase in release ... Read more...


Exposure to an enriched environment selectively increases the functional response of the pre-synaptic NMDA receptors which modulate noradrenaline release in mouse hippocampus.

30 Aug 2009 We evaluated the impact of environmental training on the functions of pre-synaptic glutamatergic NMDA and alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate (AMPA) and nicotinic receptors expressed by hippocampal noradrenergic nerve terminals. ... Read more...


Presynaptic action of neurotensin on dopamine release through inhibition of D(2) receptor function.

12 Aug 2009 BACKGROUND: Neurotensin (NT) is known to act on dopamine (DA) neurons at the somatodendritic level to regulate cell firing and secondarily enhance DA release. In addition, anatomical and indirect physiological data suggest the presence of NT ... Read more...

 

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Technical information about 'Receptors, Presynaptic'

Definition: Neurotransmitter receptors located on or near presynaptic terminals or varicosities. Presynaptic receptors which bind transmitter molecules released by the terminal itself are termed AUTORECEPTORS.

Registry Number: 0

Descriptor UI: D017661

Alternative terms: Receptors, Presynaptic; Presynaptic Receptors; Presynaptic Receptor; Receptor, Presynaptic;

Allowable Qualifiers: administration & dosage; analysis; antagonists & inhibitors; biosynthesis; blood; classification; deficiency; drug effects; genetics; history; immunology; isolation & purification; metabolism; physiology; radiation effects; therapeutic use; ultrastructure; chemistry; agonists;

Tree Number: D12.776.543.750.720.670;

History Note: 94

Technical Notes: cell surface receptors: do not confuse with NEURORECEPTORS see SENSORY rRECEPTOR CELLS or with RECEPTORS, NEUROTRANSMITTER; DF: RECEPT PRESYNAPTIC

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