Receptors, Serotonin - Metabolism
Research News and Information

Monday, November 23, 2009

Serotonin targets inhibitory synapses to induce modulation of network functions.

10 Sep 2009 The cellular effects of serotonin (5-HT), a neuromodulator with widespread influences in the central nervous system, have been investigated. Despite detailed knowledge about the molecular biology of cellular signalling, it is not possible to ... Read more...

Serotonergic-postsynaptic receptors modulate gripping-induced immobility episodes in male taiep rats.

30 Aug 2009 The Taiep rat is a myelin mutant with a motor syndrome characterized by tremor, ataxia, immobility, epilepsy, and paralysis. The rat shows a hypomyelination followed by a progressive demyelination. During immobilities taiep rats show a REM-like ... Read more...

[Neurobiological and pharmacologic aspects of atypical antipsychotic drugs]

14 Aug 2009 Atypical (second generation) antipsychotic drugs have radically changed and revolutionized the pharmacological treatment of schizophrenia and related disorders. The currently approved atypical antipsychotic drugs, which are available, are ... Read more...

Latest indexed articles for 'Receptors, Serotonin - Metabolism'

These are the very latest articles for this heading:

• Serotonergic modulation of basal ganglia circuits: complexity and therapeutic opportunities. 13 Sep 2009
• Serotonin targets inhibitory synapses to induce modulation of network functions. 10 Sep 2009
• Effects of chronic blockade of 5-HT(6) receptors on NMDA receptor subunits expression. 30 Aug 2009
• Serotonergic-postsynaptic receptors modulate gripping-induced immobility episodes in male taiep rats. 30 Aug 2009
• [Neurobiological and pharmacologic aspects of atypical antipsychotic drugs] 14 Aug 2009
• The bovine mammary gland expresses multiple functional isoforms of serotonin receptors. 2 Aug 2009
• Receptor architecture of human cingulate cortex: evaluation of the four-region neurobiological model. 30 Jul 2009
• Test-retest variability of high resolution positron emission tomography (PET) imaging of cortical serotonin (5HT2A) receptors in older, healthy adults. 4 Jul 2009
• Locomotor-activated neurons of the cat. I. Serotonergic innervation and co-localization of 5-HT7, 5-HT2A, and 5-HT1A receptors in the thoraco-lumbar spinal cord. 29 Jun 2009
• The serotonin 5-HT6 receptor: a viable drug target for treating cognitive deficits in Alzheimer's disease. 29 Jun 2009
• Antagonism of alpha1-adrenergic and serotonergic receptors in the hypoglossal motor nucleus does not prevent motoneuronal activation elicited from the posterior hypothalamus. 28 Jun 2009
• Dimebolin is a 5-HT6 antagonist with acute cognition enhancing activities. 19 Jun 2009
• Sulfonamides with the N-alkyl-N'-dialkylguanidine moiety as 5-HT7 receptor ligands. 11 Jun 2009
• Specific targeting of peripheral serotonin 5-HT(3) receptors. Synthesis, biological investigation, and structure-activity relationships. 9 Jun 2009
• Serotonin rising. 9 Jun 2009
• Human 5-HT7 receptor-induced inactivation of forskolin-stimulated adenylate cyclase by risperidone, 9-OH-risperidone and other "inactivating antagonists". 7 Jun 2009
• Serotonin neuron-dependent and -independent reduction of dyskinesia by 5-HT1A and 5-HT1B receptor agonists in the rat Parkinson model. Jun 2009
• PSD-95 is essential for hallucinogen and atypical antipsychotic drug actions at serotonin receptors. Jun 2009
• From nature to drug discovery: the indole scaffold as a 'privileged structure'. 30 May 2009
• Molecular dynamics simulation of the heterodimeric mGluR2/5HT(2A) complex. An atomistic resolution study of a potential new target in psychiatric conditions. 30 May 2009

See a longer list of these articles.

Technical information about 'Receptors, Serotonin'

Definition: Cell-surface proteins that bind SEROTONIN and trigger intracellular changes which influence the behavior of cells. Several types of serotonin receptors have been recognized which differ in their pharmacology, molecular biology, and mode of action.

Registry Number: 0

Descriptor UI: D011985

Alternative terms: Receptors, Serotonin; 5-Hydroxytryptamine Receptors; 5 Hydroxytryptamine Receptors; 5-HT Receptors; 5 HT Receptors; Receptors, 5-HT; Receptors, 5 HT; Receptors, 5-Hydroxytryptamine; Receptors, 5 Hydroxytryptamine; Serotonin Receptors; Receptors, Tryptamine; Tryptamine Receptors;

Allowable Qualifiers: administration & dosage; analysis; biosynthesis; blood; classification; deficiency; drug effects; genetics; history; immunology; isolation & purification; metabolism; physiology; radiation effects; therapeutic use; ultrastructure; chemistry;

Tree Number: D12.776.543.750.070.800; D12.776.543.750.100.800; D12.776.543.750.720.300.800;

History Note: 77

Technical Notes: GEN; prefer specifics; DF: RECEPT SEROTONIN