Receptors, Serotonin
Research News and Information

Sunday, November 22, 2009

Identification of novel indanylsulfonamide guanylhydrazones as potent 5-HT6 serotonin receptor antagonists.

6 Oct 2009 Changing the N,N-(dimethylamino)ethyl side chain in the N-[3-(aminoethyl)inden-5-yl]sulfonamide 5-HT(6) serotonin receptor agonists 1 by a conformationally rigid guanylhydrazone moiety at the indene 3-position led to the identification of the title ... Read more...

Selective serotonin receptor stimulation of the medial nucleus accumbens causes differential effects on food intake and locomotion.

29 Sep 2009 Substantial evidence suggests that pharmacological manipulations of neural serotonin pathways influence ingestive behaviors. Despite the known role of the nucleus accumbens in directing appetitive and consummatory behavior, there has been little ... Read more...

Serotonin targets inhibitory synapses to induce modulation of network functions.

10 Sep 2009 The cellular effects of serotonin (5-HT), a neuromodulator with widespread influences in the central nervous system, have been investigated. Despite detailed knowledge about the molecular biology of cellular signalling, it is not possible to ... Read more...

Latest indexed articles for 'Receptors, Serotonin'

These are the very latest articles for this heading:

• Anesthesia and pharmacogenomics: not ready for prime time. 30 Oct 2009
• Identification of novel indanylsulfonamide guanylhydrazones as potent 5-HT6 serotonin receptor antagonists. 6 Oct 2009
• Selective serotonin receptor stimulation of the medial nucleus accumbens causes differential effects on food intake and locomotion. 29 Sep 2009
• Serotonergic modulation of basal ganglia circuits: complexity and therapeutic opportunities. 13 Sep 2009
• Serotonin targets inhibitory synapses to induce modulation of network functions. 10 Sep 2009
• [Serotonin receptor gene polymorphism and analgesic sensitivity] 30 Aug 2009
• Effects of chronic blockade of 5-HT(6) receptors on NMDA receptor subunits expression. 30 Aug 2009
• Serotonergic-postsynaptic receptors modulate gripping-induced immobility episodes in male taiep rats. 30 Aug 2009
• Do variations in the 5-HT3A and 5-HT3B serotonin receptor genes (HTR3A and HTR3B) influence the occurrence of postoperative vomiting? 25 Aug 2009
• Comparative effectiveness of biomarkers and clinical indicators for predicting outcomes of SSRI treatment in Major Depressive Disorder: results of the BRITE-MD study. 25 Aug 2009
• [Neurobiological and pharmacologic aspects of atypical antipsychotic drugs] 14 Aug 2009
• Drug-induced fibrotic valvular heart disease. 13 Aug 2009
• Identification of a serotonin receptor coupled to adenylyl cyclase involved in learning-related heterosynaptic facilitation in Aplysia. 9 Aug 2009
• 5-HTR1A, 5-HTR2A, 5-HTR6, TPH1 and TPH2 polymorphisms and major depression. 3 Aug 2009
• The bovine mammary gland expresses multiple functional isoforms of serotonin receptors. 2 Aug 2009
• Receptor architecture of human cingulate cortex: evaluation of the four-region neurobiological model. 30 Jul 2009
• Translocation of a "winner" climbing fiber to the Purkinje cell dendrite and subsequent elimination of "losers" from the soma in developing cerebellum. 14 Jul 2009
• Test-retest variability of high resolution positron emission tomography (PET) imaging of cortical serotonin (5HT2A) receptors in older, healthy adults. 4 Jul 2009
• Locomotor-activated neurons of the cat. I. Serotonergic innervation and co-localization of 5-HT7, 5-HT2A, and 5-HT1A receptors in the thoraco-lumbar spinal cord. 29 Jun 2009
• The serotonin 5-HT6 receptor: a viable drug target for treating cognitive deficits in Alzheimer's disease. 29 Jun 2009

See a longer list of these articles.

Technical information about 'Receptors, Serotonin'

Definition: Cell-surface proteins that bind SEROTONIN and trigger intracellular changes which influence the behavior of cells. Several types of serotonin receptors have been recognized which differ in their pharmacology, molecular biology, and mode of action.

Registry Number: 0

Descriptor UI: D011985

Alternative terms: Receptors, Serotonin; 5-Hydroxytryptamine Receptors; 5 Hydroxytryptamine Receptors; 5-HT Receptors; 5 HT Receptors; Receptors, 5-HT; Receptors, 5 HT; Receptors, 5-Hydroxytryptamine; Receptors, 5 Hydroxytryptamine; Serotonin Receptors; Receptors, Tryptamine; Tryptamine Receptors;

Allowable Qualifiers: administration & dosage; analysis; biosynthesis; blood; classification; deficiency; drug effects; genetics; history; immunology; isolation & purification; metabolism; physiology; radiation effects; therapeutic use; ultrastructure; chemistry;

Tree Number: D12.776.543.750.070.800; D12.776.543.750.100.800; D12.776.543.750.720.300.800;

History Note: 77

Technical Notes: GEN; prefer specifics; DF: RECEPT SEROTONIN