Renin - Blood
Research News and Information

Monday, November 23, 2009

Time-dependent effects of low-dose aspirin on plasma renin activity, aldosterone, cortisol, and catecholamines.

3 Oct 2009 Studies have shown that aspirin may decrease blood pressure when given at bedtime but not when administered on awakening. However, until now, a biologically plausible mechanism of this striking phenomenon was not revealed. We investigated the effect ... Read more...

Angiotensin-(1-7), an alternative metabolite of the renin-angiotensin system, is up-regulated in human liver disease and has antifibrotic activity in the bile-duct-ligated rat.

12 Sep 2009 Ang-(1-7) (angiotensin-1-7), a peptide product of the recently described ACE (angiotensin-converting enzyme) homologue ACE2, opposes the harmful actions of AngII (angiotensin II) in cardiovascular tissues, but its role in liver disease is unknown. ... Read more...

Lack of cardiac fibrosis in a new model of high prorenin hyperaldosteronism.

9 Sep 2009 The aim of the present study was to test the hypothesis that elevation of prorenin in plasma is sufficient to induce cardiac fibrosis. Normotensive cyp1a1ren-2 transgenic rats with normal plasma prorenin and aldosterone levels were given 0.125% ... Read more...

Latest indexed articles for 'Renin - Blood'

These are the very latest articles for this heading:

• Time-dependent effects of low-dose aspirin on plasma renin activity, aldosterone, cortisol, and catecholamines. 3 Oct 2009
• Angiotensin-(1-7), an alternative metabolite of the renin-angiotensin system, is up-regulated in human liver disease and has antifibrotic activity in the bile-duct-ligated rat. 12 Sep 2009
• Lack of cardiac fibrosis in a new model of high prorenin hyperaldosteronism. 9 Sep 2009
• Enhanced tubuloglomerular feedback in mice with vascular overexpression of A1 adenosine receptors. 7 Sep 2009
• Decreased renal perfusion rapidly increases plasma membrane Na-K-ATPase in rat cortex by an angiotensin II-dependent mechanism. 31 Aug 2009
• Physiological partial aldosterone resistance in human newborns. 30 Aug 2009
• Systematic review: diagnostic procedures to differentiate unilateral from bilateral adrenal abnormality in primary aldosteronism. 30 Aug 2009
• The influence of a tilt training programme on the renin-angiotensin-aldosterone system activity in patients with vasovagal syncope. 30 Jul 2009
• [Normokalaemic primary aldosteronism due to an aldosterone-producing adrenal adenoma--Case 06/2009] 21 Jul 2009
• Effects of dietary sodium reduction on blood pressure in subjects with resistant hypertension: results from a randomized trial. 18 Jul 2009
• Magnesium sulphate attenuates arterial pressure increase during laparoscopic cholecystectomy. 15 Jul 2009
• Independent relations of left ventricular structure with the 24-hour urinary excretion of sodium and aldosterone. 4 Jul 2009
• The lactotripeptides isoleucine-proline-proline and valine-proline-proline do not inhibit the N-terminal or C-terminal angiotensin converting enzyme active sites in humans. 29 Jun 2009
• Differential effects of p38 mitogen-activated protein kinase and cyclooxygenase 2 inhibitors in a model of cardiovascular disease. 23 Jun 2009
• The effect of angiotensin-converting enzyme inhibition using captopril on energy balance and glucose homeostasis. 2 Jun 2009
• Adrenal venous sampling for primary aldosteronism and clinical outcomes after unilateral adrenalectomy: a single-center experience. 30 May 2009
• Implication of chromosome 13 on hypertension and associated disorders in Lyon hypertensive rats. 30 May 2009
• Cross-sectional relations of multiple biomarkers representing distinct biological pathways to plasma markers of collagen metabolism in the community. 30 May 2009
• Low renal mineralocorticoid receptor expression at birth contributes to partial aldosterone resistance in neonates. 26 May 2009
• Replacement of connexin 40 by connexin 45 causes ectopic localization of renin-producing cells in the kidney but maintains in vivo control of renin gene expression. 25 May 2009

See a longer list of these articles.

Technical information about 'Renin'

Definition: A highly specific (Leu-Leu) endopeptidase that generates ANGIOTENSIN I from its precursor ANGIOTENSINOGEN, leading to a cascade of reactions which elevate BLOOD PRESSURE and increase sodium retention by the kidney in the RENIN-ANGIOTENSIN SYSTEM. The enzyme was formerly listed as EC 3.4.99.19.

Registry Number: EC 3.4.23.15

Descriptor UI: D012083

Alternative terms: Renin; Angiotensinogenase; Angiotensin-Forming Enzyme; Angiotensin Forming Enzyme; Prorenin; Cryorenin; Inactive Renin; Renin, Inactive; Big Renin; Renin, Big; Preprorenin; Pre-Prorenin; Pre Prorenin;

Allowable Qualifiers: administration & dosage; adverse effects; analysis; antagonists & inhibitors; biosynthesis; blood; cerebrospinal fluid; chemical synthesis; classification; deficiency; diagnostic use; drug effects; economics; genetics; history; immunology; isolation & purification; metabolism; pharmacokinetics; pharmacology; physiology; poisoning; radiation effects; secretion; standards; supply & distribution; therapeutic use; toxicity; ultrastructure; urine; chemistry; contraindications;

Tree Number: D08.811.277.656.300.066.780; D08.811.277.656.837.750;

History Note: 1963; for PRORENIN use RENIN (NM) 1977-2003, for PREPRORENIN use RENIN (NM) 1980-2003

Technical Notes: do not confuse with RENNIN see CHYMOSIN