Renin
Research News and Information

Sunday, November 22, 2009

Time-dependent effects of low-dose aspirin on plasma renin activity, aldosterone, cortisol, and catecholamines.

3 Oct 2009 Studies have shown that aspirin may decrease blood pressure when given at bedtime but not when administered on awakening. However, until now, a biologically plausible mechanism of this striking phenomenon was not revealed. We investigated the effect ... Read more...

[Hypertension in diabetes mellitus]

25 Sep 2009 Hypertension can be detected very often in patients with diabetes mellitus. In some cases, hypertension develops as a consequence of diabetic nephropathy. Although diabetic nephropathy may occur both in type 1 and in type 2 diabetes, some ... Read more...

Angiotensin-(1-7), an alternative metabolite of the renin-angiotensin system, is up-regulated in human liver disease and has antifibrotic activity in the bile-duct-ligated rat.

12 Sep 2009 Ang-(1-7) (angiotensin-1-7), a peptide product of the recently described ACE (angiotensin-converting enzyme) homologue ACE2, opposes the harmful actions of AngII (angiotensin II) in cardiovascular tissues, but its role in liver disease is unknown. ... Read more...

Latest indexed articles for 'Renin'

These are the very latest articles for this heading:

• Time-dependent effects of low-dose aspirin on plasma renin activity, aldosterone, cortisol, and catecholamines. 3 Oct 2009
• [Hypertension in diabetes mellitus] 25 Sep 2009
• Angiotensin-(1-7), an alternative metabolite of the renin-angiotensin system, is up-regulated in human liver disease and has antifibrotic activity in the bile-duct-ligated rat. 12 Sep 2009
• Lack of cardiac fibrosis in a new model of high prorenin hyperaldosteronism. 9 Sep 2009
• Enhanced tubuloglomerular feedback in mice with vascular overexpression of A1 adenosine receptors. 7 Sep 2009
• Decreased renal perfusion rapidly increases plasma membrane Na-K-ATPase in rat cortex by an angiotensin II-dependent mechanism. 31 Aug 2009
• Physiological partial aldosterone resistance in human newborns. 30 Aug 2009
• Is there a role for direct renin inhibitors in chronic kidney disease? 30 Aug 2009
• Systematic review: diagnostic procedures to differentiate unilateral from bilateral adrenal abnormality in primary aldosteronism. 30 Aug 2009
• Quiz Page September 2009. Long-standing high-renin hypertension and hypokalemia: renin-secreting tumor of the juxtaglomerular apparatus. 30 Aug 2009
• Developmental renin expression in mice with a defective renin-angiotensin system. 24 Aug 2009
• Role of the renin-angiotensin system in autoimmune inflammation of the central nervous system. 17 Aug 2009
• Dominant renin gene mutations associated with early-onset hyperuricemia, anemia, and chronic kidney failure. 4 Aug 2009
• Vascular endothelial growth factor receptor 2 controls blood pressure by regulating nitric oxide synthase expression. Aug 2009
• Effect of rhythmic melatonin administration on clock gene expression in the suprachiasmatic nucleus and the heart of hypertensive TGR(mRen2)27 rats. 30 Jul 2009
• The influence of a tilt training programme on the renin-angiotensin-aldosterone system activity in patients with vasovagal syncope. 30 Jul 2009
• Hypertension in ethnic groups: epidemiological and clinical perspectives. 30 Jul 2009
• [The renin-angiotensin system] 30 Jul 2009
• Hypotonicity-induced Renin exocytosis from juxtaglomerular cells requires aquaporin-1 and cyclooxygenase-2. 21 Jul 2009
• [Normokalaemic primary aldosteronism due to an aldosterone-producing adrenal adenoma--Case 06/2009] 21 Jul 2009

See a longer list of these articles.

Technical information about 'Renin'

Definition: A highly specific (Leu-Leu) endopeptidase that generates ANGIOTENSIN I from its precursor ANGIOTENSINOGEN, leading to a cascade of reactions which elevate BLOOD PRESSURE and increase sodium retention by the kidney in the RENIN-ANGIOTENSIN SYSTEM. The enzyme was formerly listed as EC 3.4.99.19.

Registry Number: EC 3.4.23.15

Descriptor UI: D012083

Alternative terms: Renin; Angiotensinogenase; Angiotensin-Forming Enzyme; Angiotensin Forming Enzyme; Prorenin; Cryorenin; Inactive Renin; Renin, Inactive; Big Renin; Renin, Big; Preprorenin; Pre-Prorenin; Pre Prorenin;

Allowable Qualifiers: administration & dosage; adverse effects; analysis; antagonists & inhibitors; biosynthesis; blood; cerebrospinal fluid; chemical synthesis; classification; deficiency; diagnostic use; drug effects; economics; genetics; history; immunology; isolation & purification; metabolism; pharmacokinetics; pharmacology; physiology; poisoning; radiation effects; secretion; standards; supply & distribution; therapeutic use; toxicity; ultrastructure; urine; chemistry; contraindications;

Tree Number: D08.811.277.656.300.066.780; D08.811.277.656.837.750;

History Note: 1963; for PRORENIN use RENIN (NM) 1977-2003, for PREPRORENIN use RENIN (NM) 1980-2003

Technical Notes: do not confuse with RENNIN see CHYMOSIN