Repressor Proteins - Genetics
Research News and Information

Sunday, November 22, 2009

Association of HPV16 E6 variants with diagnostic severity in cervical cytology samples of 354 women in a US population.

29 Nov 2009 It has been suggested that DNA sequence variants of HPV16 contribute to differences in the behavior of individual cervical lesions. To address this question, we have analyzed the association of HPV16 variants with diagnostic severity in 354 ... Read more...

Novel SYT-SSX fusion transcript variants in synovial sarcoma.

30 Oct 2009 Synovial sarcoma (SS) is characterized by the t(X;18)(p11.2;q11.2) chromosomal translocation detected in >95% of cases. Through this translocation, one of the SYT genes, SYT4 on chromosome 18, is fused to one of the SSX genes on chromosome X. ... Read more...

Detailed cytogenetic and array analysis of pediatric primitive sarcomas reveals a recurrent CIC-DUX4 fusion gene event.

30 Oct 2009 Pediatric undifferentiated soft tissue sarcomas (USTS) are a diagnostically challenging group of neoplasms. Recently, a subcategory of USTS with primitive round cell morphology and a t(4;19)(q35;q13) rearrangement has been defined. The present study ... Read more...

Latest indexed articles for 'Repressor Proteins - Genetics'

These are the very latest articles for this heading:

• Association of HPV16 E6 variants with diagnostic severity in cervical cytology samples of 354 women in a US population. 29 Nov 2009
• Novel SYT-SSX fusion transcript variants in synovial sarcoma. 30 Oct 2009
• Detailed cytogenetic and array analysis of pediatric primitive sarcomas reveals a recurrent CIC-DUX4 fusion gene event. 30 Oct 2009
• Polycomb group proteins: navigators of lineage pathways led astray in cancer. 30 Oct 2009
• Recruitment of polycomb group complexes and their role in the dynamic regulation of cell fate choice. 30 Oct 2009
• Oncogenic human papillomaviruses block expression of the B-cell translocation gene-2 tumor suppressor gene. 30 Oct 2009
• Biochemical characterization of the multidrug regulator QacR distinguishes residues that are crucial to multidrug binding and induction of qacA transcription. 18 Oct 2009
• cDNA microarray expression profile in vestibular schwannoma: correlation with clinical and radiological features. 13 Oct 2009
• Rbpj cell autonomous regulation of retinal ganglion cell and cone photoreceptor fates in the mouse retina. 12 Oct 2009
• Spred2 interaction with the late endosomal protein NBR1 down-regulates fibroblast growth factor receptor signaling. 10 Oct 2009
• Functional characterization of the interactions between endosomal adaptor protein APPL1 and the NuRD co-repressor complex. 10 Oct 2009
• Modulation of vitamin d receptor activity by the corepressor hairless: differential effects of hairless isoforms. 7 Oct 2009
• CCCTC-binding factor and the transcription factor T-bet orchestrate T helper 1 cell-specific structure and function at the interferon-gamma locus. 6 Oct 2009
• Prohibitin couples diapause signalling to mitochondrial metabolism during ageing in C. elegans. 6 Oct 2009
• A computational study of lambda-lac mutants. 4 Oct 2009
• The Arabidopsis ATAF1, a NAC transcription factor, is a negative regulator of defense responses against necrotrophic fungal and bacterial pathogens. 29 Sep 2009
• Novel features of boundary cap cells revealed by the analysis of newly identified molecular markers. 29 Sep 2009
• The cell adhesion molecules Echinoid and Friend of Echinoid coordinate cell adhesion and cell signaling to regulate the fidelity of ommatidial rotation in the Drosophila eye. 29 Sep 2009
• Meis2 competes with the Groucho co-repressor Tle4 for binding to Otx2 and specifies tectal fate without induction of a secondary midbrain-hindbrain boundary organizer. 29 Sep 2009
• Human papillomavirus typing and viral gene expression analysis for the triage of women with abnormal results from papanicolaou test smears to colposcopy. 29 Sep 2009

See a longer list of these articles.

Technical information about 'Repressor Proteins'

Definition: Proteins which are normally bound to the operator locus of an operon, thereby preventing transcription of the structural genes. In enzyme induction, the substrate of the inducible enzyme binds to the repressor protein, causing its release from the operator and freeing the structural genes for transcription. In enzyme repression, the end product of the enzyme sequence binds to the free repressor protein, the resulting complex then binds to the operator and prevents transcription of the structural genes.

Registry Number: 0

Descriptor UI: D012097

Alternative terms: Repressor Proteins; Proteins, Repressor; Repressor Molecules; Molecules, Repressor; Lac Repressors; Repressors, Lac;

Allowable Qualifiers: supply & distribution; therapeutic use; toxicity; ultrastructure; urine; chemistry; contraindications; agonists; administration & dosage; adverse effects; analysis; antagonists & inhibitors; biosynthesis; blood; cerebrospinal fluid; chemical synthesis; classification; diagnostic use; drug effects; economics; genetics; history; immunology; isolation & purification; metabolism; pharmacokinetics; pharmacology; physiology; poisoning; radiation effects; secretion; standards;

Tree Number: D12.776.930.700;

History Note: 91(79); was see under TRANSCRIPTION FACTORS 1979-90

Technical Notes: transcription factors; /biosyn /drug eff /physiol permitted