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Repressor Proteins
Research News and Information
Definition of 'Repressor Proteins'Proteins which are normally bound to the operator locus of an operon, thereby preventing transcription of the structural genes. In enzyme induction, the substrate of the inducible enzyme binds to the repressor protein, causing its release from the operator and freeing the structural genes for transcription. In enzyme repression, the end product of the enzyme sequence binds to the free repressor protein, the resulting complex then binds to the operator and prevents transcription of the structural genes. |
Sunday, November 22, 2009
29 Nov 2009 
It has been suggested that DNA sequence variants of HPV16 contribute to differences in the behavior of individual cervical lesions. To address this question, we have analyzed the association of HPV16 variants with diagnostic severity in 354 ... Read more...
Role of Wnt inhibitory factor-1 and Wnt/wingless signaling in choroid plexus tumors.
29 Nov 2009 Little is known on pathways involved in the pathogenesis of choroid plexus tumors (CPTs). The finding of overexpression of Wnt inhibitory factor-1 (Wif-1) prompted us to investigate the functional role of Wif-1 as well as nuclear accumulation of ... Read more...
12 Nov 2009 Curli are adhesive fimbriae of Escherichia coli and Salmonella enterica. Expression of curli (csgA) and cellulose (bcsA) is co-activated by the transcriptional activator CsgD. In this study, we investigated the contribution of curli and cellulose to ... Read more...
Latest indexed articles for 'Repressor Proteins'
These are the very latest articles for this heading:
- Association of HPV16 E6 variants with diagnostic severity in cervical cytology samples of 354 women in a US population. 29 Nov 2009
- Role of Wnt inhibitory factor-1 and Wnt/wingless signaling in choroid plexus tumors. 29 Nov 2009
- Synergistic role of curli and cellulose in cell adherence and biofilm formation of attaching and effacing Escherichia coli and identification of Fis as a negative regulator of curli. 12 Nov 2009
- Ring1B contains a ubiquitin-like docking module for interaction with Cbx proteins. 8 Nov 2009
- Vaccination against HPV-16 oncoproteins for vulvar intraepithelial neoplasia. 3 Nov 2009
- Necdin: a multi functional protein with potential tumor suppressor role? 30 Oct 2009
- Novel SYT-SSX fusion transcript variants in synovial sarcoma. 30 Oct 2009
- Detailed cytogenetic and array analysis of pediatric primitive sarcomas reveals a recurrent CIC-DUX4 fusion gene event. 30 Oct 2009
- Polycomb group proteins: navigators of lineage pathways led astray in cancer. 30 Oct 2009
- Recruitment of polycomb group complexes and their role in the dynamic regulation of cell fate choice. 30 Oct 2009
- Oncogenic human papillomaviruses block expression of the B-cell translocation gene-2 tumor suppressor gene. 30 Oct 2009
- RUNX3-mediated repression of RUNX1 in B cells. 30 Oct 2009
- Biochemical characterization of the multidrug regulator QacR distinguishes residues that are crucial to multidrug binding and induction of qacA transcription. 18 Oct 2009
- cDNA microarray expression profile in vestibular schwannoma: correlation with clinical and radiological features.
13 Oct 2009 - Rbpj cell autonomous regulation of retinal ganglion cell and cone photoreceptor fates in the mouse retina. 12 Oct 2009
- Spred2 interaction with the late endosomal protein NBR1 down-regulates fibroblast growth factor receptor signaling. 10 Oct 2009
- Functional characterization of the interactions between endosomal adaptor protein APPL1 and the NuRD co-repressor complex. 10 Oct 2009
- Modulation of vitamin d receptor activity by the corepressor hairless: differential effects of hairless isoforms. 7 Oct 2009
- CCCTC-binding factor and the transcription factor T-bet orchestrate T helper 1 cell-specific structure and function at the interferon-gamma locus. 6 Oct 2009
- Prohibitin couples diapause signalling to mitochondrial metabolism during ageing in C. elegans. 6 Oct 2009
See a longer list of these articles.
Technical information about 'Repressor Proteins'
Definition: Proteins which are normally bound to the operator locus of an operon, thereby preventing transcription of the structural genes. In enzyme induction, the substrate of the inducible enzyme binds to the repressor protein, causing its release from the operator and freeing the structural genes for transcription. In enzyme repression, the end product of the enzyme sequence binds to the free repressor protein, the resulting complex then binds to the operator and prevents transcription of the structural genes.
Registry Number: 0
Descriptor UI: D012097
Alternative terms: Repressor Proteins; Proteins, Repressor; Repressor Molecules; Molecules, Repressor; Lac Repressors; Repressors, Lac;
Allowable Qualifiers: supply & distribution; therapeutic use; toxicity; ultrastructure; urine; chemistry; contraindications; agonists; administration & dosage; adverse effects; analysis; antagonists & inhibitors; biosynthesis; blood; cerebrospinal fluid; chemical synthesis; classification; diagnostic use; drug effects; economics; genetics; history; immunology; isolation & purification; metabolism; pharmacokinetics; pharmacology; physiology; poisoning; radiation effects; secretion; standards;
Tree Number: D12.776.930.700;
History Note: 91(79); was see under TRANSCRIPTION FACTORS 1979-90
Technical Notes: transcription factors; /biosyn /drug eff /physiol permitted