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Restless Legs Syndrome - Drug therapy
Research News and Information
Definition of 'Restless Legs Syndrome'A disorder characterized by aching or burning sensations in the lower and rarely the upper extremities that occur prior to sleep or may awaken the patient from sleep. Complying with an irresistible urge to move the affected limbs brings temporary relief. Sleep may become disrupted, resulting in excessive daytime hypersomnolence. This condition may be associated with UREMIA; DIABETES MELLITUS; and rheumatoid arthritis. Restless Legs Syndrome differs from NOCTURNAL MYOCLONUS SYNDROME in that in the latter condition the individual does not report adverse sensory stimuli and it is primarily a sleep-associated movement disorder. (Adams et al., Principles of Neurology, 6th ed, p387; Schweiz Rundsch Med Prax 1997 Apr 30;86(18):732-736) |
Monday, March 22, 2010
29 Sep 2009 
Ropinirole hydrochloride (REQUIP, ADARTREL) and pramipexole dihydrochloride (MIRAPEX, SIFROL) are two putative dopamine D(3) receptor subtype-selective agonists recently approved by the FDA for the treatment of 'restless legs syndrome' (RLS). RLS is ... Read more...
[Sleep-related movement disorders]
22 Sep 2009 BACKGROUND: Restless legs syndrome is a common cause of sleep problems; the condition is often associated with periodic limb movement during sleep. The syndrome is probably under-diagnosed and under-treated. MATERIAL AND METHODS: The article is ... Read more...
16 Aug 2009 BACKGROUND: Traditional treatment approaches for the management of restless legs syndrome (RLS) and Parkinson's disease (PD) include the use of medications that either directly or indirectly increase dopamine levels. In turn, a potential adverse ... Read more...
Latest indexed articles for 'Restless Legs Syndrome - Drug therapy'
These are the very latest articles for this heading:
- Critical review of ropinirole and pramipexole - putative dopamine D(3)-receptor selective agonists - for the treatment of RLS. 29 Sep 2009
- [Sleep-related movement disorders] 22 Sep 2009
- An exploratory retrospective evaluation of ropinirole-associated psychotic symptoms in an outpatient population treated for restless legs syndrome or Parkinson's disease. 16 Aug 2009
- Restless legs syndrome. 30 Jul 2009
- A randomized, double-blind, placebo controlled, multi-center study of intravenous iron sucrose and placebo in the treatment of restless legs syndrome. 28 Jul 2009
- Lack of pharmacokinetic interactions between transdermal rotigotine and oral levodopa/carbidopa. 21 Jul 2009
- Excessive Daytime sleepiness in idiopathic restless legs syndrome: characteristics and evolution under dopaminergic treatment. 9 Jul 2009
- Too soon for dopaminergics in the management of restless legs syndrome in children.
25 May 2009 - Oxcarbazepine treatment of restless legs syndrome: three case reports. 29 Apr 2009
- Catecholamine excess in a patient with restless legs syndrome treated with levodopa and benserazide. 29 Apr 2009
- Leg cramps and restless legs syndrome during pregnancy. 29 Apr 2009
- A case of compulsive behaviors observed in a restless legs syndrome patient treated with a dopamine agonist. 29 Apr 2009
- Bilateral restless legs affecting a phantom limb, treated with dopamine agonists. 29 Apr 2009
- Effect of non-ergot dopamine agonists on health-related quality of life of patients with restless legs syndrome. 26 Apr 2009
- Recent advances in the diagnosis, genetics and treatment of restless legs syndrome. 25 Apr 2009
- Dopamine agonists restore cortical plasticity in patients with idiopathic restless legs syndrome. 13 Apr 2009
- Dopamine dysregulation syndrome in a patient with restless legs syndrome. 30 Mar 2009
- [Restless legs, restless nights: therapeutic options in RLS] 24 Mar 2009
- Drug hoarding: a case of atypical dopamine dysregulation syndrome in a RLS patient. 13 Mar 2009
- Treatment of restless legs syndrome with iron infusion therapy. 27 Feb 2009
See a longer list of these articles.
Technical information about 'Restless Legs Syndrome'
Definition: A disorder characterized by aching or burning sensations in the lower and rarely the upper extremities that occur prior to sleep or may awaken the patient from sleep. Complying with an irresistible urge to move the affected limbs brings temporary relief. Sleep may become disrupted, resulting in excessive daytime hypersomnolence. This condition may be associated with UREMIA; DIABETES MELLITUS; and rheumatoid arthritis. Restless Legs Syndrome differs from NOCTURNAL MYOCLONUS SYNDROME in that in the latter condition the individual does not report adverse sensory stimuli and it is primarily a sleep-associated movement disorder. (Adams et al., Principles of Neurology, 6th ed, p387; Schweiz Rundsch Med Prax 1997 Apr 30;86(18):732-736)
Descriptor UI: D012148
Alternative terms: Restless Legs Syndrome; Restless Legs; Ekbom Syndrome; Syndrome, Ekbom; Ekbom's Syndrome; Ekboms Syndrome; Syndrome, Ekbom's;
Allowable Qualifiers: blood; cerebrospinal fluid; chemically induced; classification; complications; congenital; diagnosis; diet therapy; drug therapy; economics; embryology; enzymology; ethnology; etiology; genetics; history; immunology; metabolism; microbiology; mortality; nursing; epidemiology; parasitology; pathology; physiopathology; prevention & control; psychology; radiography; radionuclide imaging; radiotherapy; rehabilitation; surgery; therapy; urine; veterinary; ultrasonography; virology;
Tree Number: C10.886.425.800.700; C10.886.659.634; F03.870.400.800.700; F03.870.664.634;
History Note: 2000(1973)