Retinoid X Receptor alpha
Research News and Information

Sunday, November 22, 2009

Epigenetic modulation of the retinoid X receptor alpha by green tea in the azoxymethane-Apc Min/+ mouse model of intestinal cancer.

29 Sep 2009 We investigated the possible mechanisms of inhibition of colorectal carcinogenesis by green tea (GT) in azoxymethane-treated (AOM) Apc(Min/+) mice. Mice received water or a 0.6% (w/v) solution of GT as the only source of beverage. GT treatment ... Read more...

Dynamic interactions and cooperative functions of PGC-1alpha and MED1 in TRalpha-mediated activation of the brown-fat-specific UCP-1 gene.

22 Sep 2009 PGC-1alpha is an inducible nuclear receptor coactivator with direct functions in both p300-mediated chromatin remodeling and Mediator-dependent transcription in vitro. Here, we have employed the PPARgamma- and TRalpha-activated brown adipose ... Read more...

Retinoid X receptor alpha participation in dexamethasone-induced rat bile acid coenzyme A-amino acid N-acyltransferase expression in septic liver.

30 Jul 2009 To test the hypothesis that dexamethasone (Dex) treatment would restore rat hepatic bile acid coenzyme A-amino acid N-acyltransferase (rBAT) expression in septic rats after cecal ligation and puncture by increasing expression of retinoic acid X ... Read more...

Latest indexed articles for 'Retinoid X Receptor alpha'

These are the very latest articles for this heading:

• Epigenetic modulation of the retinoid X receptor alpha by green tea in the azoxymethane-Apc Min/+ mouse model of intestinal cancer. 29 Sep 2009
• Dynamic interactions and cooperative functions of PGC-1alpha and MED1 in TRalpha-mediated activation of the brown-fat-specific UCP-1 gene. 22 Sep 2009
• Retinoid X receptor alpha participation in dexamethasone-induced rat bile acid coenzyme A-amino acid N-acyltransferase expression in septic liver. 30 Jul 2009
• Differential action on coregulator interaction defines inverse retinoid agonists and neutral antagonists. 27 May 2009
• Involvement of Vitamin D receptor in the intestinal induction of human ABCB1. 19 May 2009
• A unique cytoplasmic localization of retinoic acid receptor-gamma and its regulations. 3 May 2009
• The peroxisome proliferator-activated receptor gamma/retinoid X receptor alpha heterodimer targets the histone modification enzyme PR-Set7/Setd8 gene and regulates adipogenesis through a positive feedback loop. 2 May 2009
• Pyrazine arotinoids with inverse agonist activities on the retinoid and rexinoid receptors. 2 May 2009
• Retinoic acid activates monoamine oxidase B promoter in human neuronal cells. 26 Apr 2009
• Activation of the PI3 kinase pathway by retinoic acid mediates sodium/iodide symporter induction and iodide transport in MCF-7 breast cancer cells. 5 Apr 2009
• Retinoid X receptor overexpression desensitizes laryngeal epithelium to carcinogenic effects associated with epidermal growth factor receptor upregulation. 30 Mar 2009
• Effects of MAPK signaling on 1,25-dihydroxyvitamin D-mediated CYP24 gene expression in the enterocyte-like cell line, Caco-2. 30 Mar 2009
• IGFBP-3, hypoxia and TNF-alpha inhibit adiponectin transcription. 22 Mar 2009
• RXRA gene variations influence Alzheimer's disease risk and cholesterol metabolism. 27 Feb 2009
• The aryl hydrocarbon receptor activator benzo[a]pyrene enhances vitamin D3 catabolism in macrophages. 23 Feb 2009
• Differential expression of nuclear receptors in T helper cells. 30 Jan 2009
• Suppression of pancreatic carcinoma growth by activating peroxisome proliferator-activated receptor gamma involves angiogenesis inhibition. 26 Jan 2009
• Mechanisms of resistance of hepatocyte retinoid X receptor alpha-null mice to WY-14,643-induced hepatocyte proliferation and cholestasis. 25 Jan 2009
• Structure of full-length PPARgamma-RXRalpha: a snapshot of a functional complex? 5 Jan 2009
• Adipocyte-specific expression of murine resistin is mediated by synergism between peroxisome proliferator-activated receptor gamma and CCAAT/enhancer-binding proteins. 3 Jan 2009

See a longer list of these articles.

Technical information about 'Retinoid X Receptor alpha'

Definition: A nuclear transcription factor. Heterodimerization with PPAR GAMMA is important in regulation of GLUCOSE metabolism and CELL GROWTH PROCESSES.

Registry Number: 0

Descriptor UI: D047490

Alternative terms: Retinoid X Receptor alpha; RXR alpha Receptor; Receptor, RXR alpha;

Allowable Qualifiers: administration & dosage; adverse effects; analysis; antagonists & inhibitors; biosynthesis; blood; cerebrospinal fluid; chemical synthesis; classification; deficiency; diagnostic use; drug effects; economics; genetics; history; immunology; isolation & purification; metabolism; pharmacokinetics; pharmacology; physiology; poisoning; radiation effects; secretion; standards; supply & distribution; therapeutic use; toxicity; ultrastructure; urine; chemistry; contraindications; agonists;

Tree Number: D12.776.826.701.500.500; D12.776.930.675.500.500;

History Note: 2005