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RNA, Double-Stranded
Research News and Information
Definition of 'RNA, Double-Stranded'RNA consisting of two strands as opposed to the more prevalent single-stranded RNA. Most of the double-stranded segments are formed from transcription of DNA by intramolecular base-pairing of inverted complementary sequences separated by a single-stranded loop. Some double-stranded segments of RNA are normal in all organisms. Common names: RNA, Double-Stranded; RNA, Double Stranded; Double-Stranded RNA; Double Stranded RNA |
Sunday, November 22, 2009
The dsRNA-mimetic poly (I:C) and IL-18 synergize for IFNgamma and TNFalpha expression.
13 Sep 2009 
Interleukin (IL)-18 bioactivity and dsRNA sensing by receptors of innate immunity are key components of anti-viral host defense. Despite extensive data on signal transduction activated by both pathways knowledge on cross-communication is incomplete. ... Read more...
Genetic determinants of mate recognition in Brachionus manjavacas (Rotifera).
7 Sep 2009 BACKGROUND: Mate choice is of central importance to most animals, influencing population structure, speciation, and ultimately the survival of a species. Mating behavior of male brachionid rotifers is triggered by the product of a chemosensory gene, ... Read more...
Brain tumor immunotherapy with type-1 polarizing strategies.
30 Aug 2009 Although the safety of vaccine approaches for central nervous system (CNS) malignancies has been established in early phase clinical trials, the success of a vaccine strategy will depend critically on the ability of effector T cells to home in to ... Read more...
Latest indexed articles for 'RNA, Double-Stranded'
These are the very latest articles for this heading:
- Silence of the budding yeast.
29 Sep 2009 - The dsRNA-mimetic poly (I:C) and IL-18 synergize for IFNgamma and TNFalpha expression. 13 Sep 2009
- Genetic determinants of mate recognition in Brachionus manjavacas (Rotifera). 7 Sep 2009
- Brain tumor immunotherapy with type-1 polarizing strategies. 30 Aug 2009
- Induction of apoptosis in the synovium of mice with autoantibody-mediated arthritis by the intraarticular injection of double-stranded MicroRNA-15a. 30 Aug 2009
- MicroRNA-140 is expressed in differentiated human articular chondrocytes and modulates interleukin-1 responses. 30 Aug 2009
- The promise of advanced imaging techniques for the detection of hepatitis C virus antigens in the infected liver. 29 Aug 2009
- An RNA-dependent RNA polymerase formed by TERT and the RMRP RNA. 21 Aug 2009
- C3PO, an endoribonuclease that promotes RNAi by facilitating RISC activation. 5 Aug 2009
- Activation of MDA5 requires higher-order RNA structures generated during virus infection. 3 Aug 2009
- 2'-5'-Oligoadenylate synthetase is activated by a specific RNA sequence motif. 3 Aug 2009
- Targeted activation of innate immunity for therapeutic induction of autophagy and apoptosis in melanoma cells. 2 Aug 2009
- Therapeutic opportunities of small interfering RNA. 30 Jul 2009
- Febrile seizures: characterization of double-stranded RNA-induced gene expression. 30 Jul 2009
- Endo-siRNAs depend on a new isoform of loquacious and target artificially introduced, high-copy sequences. 28 Jul 2009
- Avian reovirus sigmaA localizes to the nucleolus and enters the nucleus by a nonclassical energy- and carrier-independent pathway. 27 Jul 2009
- Visualizing hepatitis C virus infections in human liver by two-photon microscopy. 22 Jul 2009
- RNA polymerase III detects cytosolic DNA and induces type I interferons through the RIG-I pathway. 21 Jul 2009
- Ars2 regulates both miRNA- and siRNA- dependent silencing and suppresses RNA virus infection in Drosophila. 21 Jul 2009
- Transient transfection of Cryptosporidium parvum using green fluorescent protein (GFP) as a marker. 20 Jul 2009
See a longer list of these articles.
Technical information about 'RNA, Double-Stranded'
Definition: RNA consisting of two strands as opposed to the more prevalent single-stranded RNA. Most of the double-stranded segments are formed from transcription of DNA by intramolecular base-pairing of inverted complementary sequences separated by a single-stranded loop. Some double-stranded segments of RNA are normal in all organisms.
Registry Number: 0
Descriptor UI: D012330
Alternative terms: RNA, Double-Stranded; RNA, Double Stranded; Double-Stranded RNA; Double Stranded RNA;
Allowable Qualifiers: administration & dosage; adverse effects; analysis; antagonists & inhibitors; biosynthesis; blood; cerebrospinal fluid; chemical synthesis; classification; diagnostic use; drug effects; economics; genetics; history; immunology; isolation & purification; metabolism; pharmacokinetics; pharmacology; physiology; poisoning; radiation effects; secretion; standards; supply & distribution; therapeutic use; toxicity; ultrastructure; urine; chemistry; contraindications; agonists;
Tree Number: D13.444.735.490;
History Note: 80
Technical Notes: IM; /drug eff /ultrastruct permitted; DF: DSRNA