RNA Interference - Physiology
Research News and Information

Monday, November 23, 2009

Temperature entrainment of Drosophila's circadian clock involves the gene nocte and signaling from peripheral sensory tissues to the brain.

27 Oct 2009 Circadian clocks are synchronized by the natural day/night and temperature cycles. Our previous work demonstrated that synchronization by temperature is a tissue autonomous process, similar to synchronization by light. We show here that this is ... Read more...

Roles of disrupted-in-schizophrenia 1-interacting protein girdin in postnatal development of the dentate gyrus.

22 Sep 2009 Disrupted-In-Schizophrenia 1 (DISC1), a susceptibility gene for major psychiatric disorders, regulates neuronal migration and differentiation during mammalian brain development. Although roles for DISC1 in postnatal neurogenesis in the dentate gyrus ... Read more...

EFHC1 interacts with microtubules to regulate cell division and cortical development.

4 Sep 2009 Mutations in the EFHC1 gene are linked to juvenile myoclonic epilepsy (JME), one of the most frequent forms of idiopathic generalized epilepsies. JME is associated with subtle alterations of cortical and subcortical architecture, but the underlying ... Read more...

Latest indexed articles for 'RNA Interference - Physiology'

These are the very latest articles for this heading:

• Temperature entrainment of Drosophila's circadian clock involves the gene nocte and signaling from peripheral sensory tissues to the brain. 27 Oct 2009
• TR(I)Pping towards treatment for ischemia. 29 Sep 2009
• Roles of disrupted-in-schizophrenia 1-interacting protein girdin in postnatal development of the dentate gyrus. 22 Sep 2009
• EFHC1 interacts with microtubules to regulate cell division and cortical development. 4 Sep 2009
• Identification of an RNA-dependent RNA polymerase in Drosophila involved in RNAi and transposon suppression. 30 Aug 2009
• PACS-1 mediates phosphorylation-dependent ciliary trafficking of the cyclic-nucleotide-gated channel in olfactory sensory neurons. 24 Aug 2009
• Control of chicken CR1 retrotransposons is independent of Dicer-mediated RNA interference pathway. 17 Aug 2009
• Dynamic Pax6 expression during the neurogenic cell cycle influences proliferation and cell fate choices of retinal progenitors. 15 Aug 2009
• Overexpression of protease-activated receptor-1 contributes to melanoma metastasis via regulation of connexin 43. 13 Aug 2009
• The DOUBLETIME protein kinase regulates phosphorylation of the Drosophila PDP1epsilon. 3 Aug 2009
• RNAi screening: tips and techniques. 30 Jul 2009
• A critical step for postsynaptic F-actin organization: regulation of Baz/Par-3 localization by aPKC and PTEN. 30 Jul 2009
• Progress and challenges in RNA interference therapy for Huntington disease. 30 Jul 2009
• Dose optimization for long-term rAAV-mediated RNA interference in the nigrostriatal projection neurons. 5 Jul 2009
• NgR RNA interference, combined with zymosan intravitreal injection, enhances optic nerve regeneration. 30 Jun 2009
• Rapid screening of RNA silencing suppressors by using a recombinant virus derived from beet necrotic yellow vein virus. 29 Jun 2009
• Repression of BMI1 in normal and leukemic human CD34(+) cells impairs self-renewal and induces apoptosis. 23 Jun 2009
• Inhibition of coxsackievirus B3 and related enteroviruses by antiviral short interfering RNA pools produced using phi6 RNA-dependent RNA polymerase. 22 Jun 2009
• Regulation of postsynaptic structure and function by an A-kinase anchoring protein-membrane-associated guanylate kinase scaffolding complex. 15 Jun 2009
• Allele-specific RNAi mitigates phenotypic progression in a transgenic model of Alzheimer's disease. 14 Jun 2009

See a longer list of these articles.

Technical information about 'RNA Interference'

Definition: A gene silencing phenomenon whereby specific dsRNAs (RNA, DOUBLE-STRANDED) trigger the degradation of homologous mRNA (RNA, MESSENGER). The specific dsRNAs are processed into SMALL INTERFERING RNA (siRNA) which serves as a guide for cleavage of the homologous mRNA in the RNA-INDUCED SILENCING COMPLEX. DNA METHYLATION may also be triggered during this process.

Descriptor UI: D034622

Alternative terms: RNA Interference; Interference, RNA; Gene Silencing, Post-Transcriptional; Gene Silencing, Post Transcriptional; Post-Transcriptional Gene Silencings; Silencing, Post-Transcriptional Gene; Post-Transcriptional Gene Silencing; Post Transcriptional Gene Silencing; Posttranscriptional Gene Silencing; Gene Silencing, Posttranscriptional; Gene Silencings, Posttranscriptional; RNA Silencing; Cosuppression; Co-Suppression; Co Suppression;

Related Mesh Headings: RNA, Small Interfering; RNA-Induced Silencing Complex;

Allowable Qualifiers: drug effects; immunology; physiology; radiation effects;

Tree Number: G05.355.315.203.374.790;

History Note: 2003