RNA, Messenger - Biosynthesis
Research News and Information

Saturday, November 21, 2009

PARP1 expression in pediatric central nervous system tumors.

13 Dec 2009 BACKGROUND: Despite advances in therapy, outcome in many high-grade pediatric central nervous system (CNS) tumors remains poor. The focus of neuro-oncology research has thus turned towards identifying novel therapeutic targets. Poly(ADP-ribose) ... Read more...

Decreased brain edema after collagenase-induced intracerebral hemorrhage in mice lacking the inducible nitric oxide synthase gene. Laboratory investigation.

30 Oct 2009 OBJECT: Hematoma size and brain edema after intracerebral hemorrhage (ICH) are important prognostic factors. Inducible nitric oxide synthase (iNOS) is induced after cerebral ischemia and is known to be involved in secondary neuronal injury, but its ... Read more...

Androgen receptor as a potential sign of prostate cancer metastasis.

30 Oct 2009 BACKGROUND: Androgen receptor (AR) expression and its modulation through the carcinogenesis process have been investigated in several studies with conflicting results. MATERIALS AND METHODS: In situ hybridization and immunocytochemistry were used to ... Read more...

Latest indexed articles for 'RNA, Messenger - Biosynthesis'

These are the very latest articles for this heading:

• PARP1 expression in pediatric central nervous system tumors. 13 Dec 2009
• Decreased brain edema after collagenase-induced intracerebral hemorrhage in mice lacking the inducible nitric oxide synthase gene. Laboratory investigation. 30 Oct 2009
• Androgen receptor as a potential sign of prostate cancer metastasis. 30 Oct 2009
• In vitro propagation and characterization of neoplastic stem/progenitor-like cells from human prostate cancer tissue. 30 Oct 2009
• Preliminary evaluation of the effect of dutasteride on PCA3 in post-DRE urine sediments: a randomized, open-label, parallel-group pilot study. 30 Oct 2009
• Genetic effect of CysLTR2 polymorphisms on its mRNA synthesis and stabilization. 18 Oct 2009
• Enhanced maternal aggression and associated changes in neuropeptide gene expression in multiparous rats. 29 Sep 2009
• Maternal nutrient restriction during early fetal kidney development attenuates the renal innate inflammatory response in obese young adult offspring. 14 Sep 2009
• Microgram-order ammonium perfluorooctanoate may activate mouse peroxisome proliferator-activated receptor alpha, but not human PPARalpha. 10 Sep 2009
• Enhanced tubuloglomerular feedback in mice with vascular overexpression of A1 adenosine receptors. 7 Sep 2009
• Insulin receptor substrate-1 suppresses transforming growth factor-beta1-mediated epithelial-mesenchymal transition. 6 Sep 2009
• Mouse mammary tumor virus p75 and p110 CUX1 transgenic mice develop mammary tumors of various histologic types. 6 Sep 2009
• mTOR signal and hypoxia-inducible factor-1 alpha regulate CD133 expression in cancer cells. 6 Sep 2009
• Inactivation of the Carney complex gene 1 (protein kinase A regulatory subunit 1A) inhibits SMAD3 expression and TGF beta-stimulated apoptosis in adrenocortical cells. 6 Sep 2009
• VDR and MEK-ERK dependent induction of the antimicrobial peptide cathelicidin in keratinocytes by lithocholic acid. 3 Sep 2009
• Identification of NR4A2 as a transcriptional activator of IL-8 expression in human inflammatory arthritis. Sep 2009
• The expression of the nuclear receptors NR5A1 and NR5A2 and transcription factor GATA6 correlates with steroidogenic gene expression in the bovine corpus luteum. 30 Aug 2009
• Gene expression during the oocyte-to-embryo transition in mammals. 30 Aug 2009
• Gene expression profiling during early response to injury and microbial challenges in the silkworm, Bombyx mori. 30 Aug 2009
• Evaluation of angiogenic activities of hyaluronan oligosaccharides of defined minimum size. 27 Aug 2009

See a longer list of these articles.

Technical information about 'RNA, Messenger'

Definition: RNA sequences that serve as templates for protein synthesis. Bacterial mRNAs are generally primary transcripts in that they do not require post-transcriptional processing. Eukaryotic mRNA is synthesized in the nucleus and must be exported to the cytoplasm for translation. Most eukaryotic mRNAs have a sequence of polyadenylic acid at the 3' end, referred to as the poly(A) tail. The function of this tail is not known for certain, but it may play a role in the export of mature mRNA from the nucleus as well as in helping stabilize some mRNA molecules by retarding their degradation in the cytoplasm.

Registry Number: 0

Descriptor UI: D012333

Alternative terms: RNA, Messenger; mRNA; Messenger RNA; RNA, Polyadenylated; Polyadenylated RNA; Poly(A)+ RNA; Poly(A) RNA; Poly(A) Tail; mRNA, Non-Polyadenylated; mRNA, Non Polyadenylated; Non-Polyadenylated mRNA; Non Polyadenylated mRNA; mRNA, Polyadenylated; RNA, Messenger, Polyadenylated; Polyadenylated mRNA; Messenger RNA, Polyadenylated; Polyadenylated Messenger RNA; RNA, Polyadenylated Messenger; Poly(A)+ mRNA;

Allowable Qualifiers: administration & dosage; adverse effects; analysis; antagonists & inhibitors; biosynthesis; blood; cerebrospinal fluid; chemical synthesis; classification; diagnostic use; drug effects; economics; genetics; history; immunology; isolation & purification; metabolism; pharmacokinetics; pharmacology; physiology; poisoning; radiation effects; secretion; standards; supply & distribution; therapeutic use; toxicity; ultrastructure; urine; chemistry; contraindications; agonists;

Tree Number: D13.444.735.544;

Online Note: use RNA, MESSENGER (NM) to search MRNA, NON-POLYADENYLATED 1981-94, MRNA, POLYADENYLATED 1980-94, & POLY(A)+ RNA 1980-94

History Note: 65(64); MRNA, NON-POLYADENYLATED was NON-POLYADENYLATED MRNA (NM) 1981-94; MRNA, POLYADENYLATED was POLYADENYLATED MRNA (NM) 1980-94; POLY(A)+ RNA was SY to POLY(A) RNA (NM) 1980-94

Technical Notes: IM; /drug eff /ultrastruct permitted; DF: note short X ref