Salicylic Acids - Metabolism
Research News and Information

Sunday, November 22, 2009

Crystal structure of dicamba monooxygenase: a Rieske nonheme oxygenase that catalyzes oxidative demethylation.

13 Jul 2009 Dicamba (3,6-dichloro-2-methoxybenzoic acid) is a widely used herbicide that is efficiently degraded by soil microbes. These microbes use a novel Rieske nonheme oxygenase, dicamba monooxygenase (DMO), to catalyze the oxidative demethylation of ... Read more...

Photonucleophilic addition of the epsilon-amino group of lysine to a triflusal metabolite as a mechanistic key to photoallergy mediated by the parent drug.

29 Jun 2009 A mechanism for triflusal-induced photoallergy involving complexation of 2-hydroxy-4-trifluoromethylbenzoic acid with site I of human serum albumin and subsequent formation of a covalent adduct by photoreaction between a metabolite and a neighboring ... Read more...

Structural elucidation of metabolites of ginkgolic acid in rat liver microsomes by ultra-performance liquid chromatography/electrospray ionization tandem mass spectrometry and hydrogen/deuterium exchange.

29 Jun 2009 Ginkgolic acids have been shown to possess allergenic as well as genotoxic and cytotoxic properties. The question arises whether the metabolism of ginkgolic acids in the liver could decrease or increase their toxicity. In this study, the in vitro ... Read more...

Latest indexed articles for 'Salicylic Acids - Metabolism'

These are the very latest articles for this heading:

• Crystal structure of dicamba monooxygenase: a Rieske nonheme oxygenase that catalyzes oxidative demethylation. 13 Jul 2009
• Photonucleophilic addition of the epsilon-amino group of lysine to a triflusal metabolite as a mechanistic key to photoallergy mediated by the parent drug. 29 Jun 2009
• Structural elucidation of metabolites of ginkgolic acid in rat liver microsomes by ultra-performance liquid chromatography/electrospray ionization tandem mass spectrometry and hydrogen/deuterium exchange. 29 Jun 2009
• Roles of a membrane-bound caleosin and putative peroxygenase in biotic and abiotic stress responses in Arabidopsis. 7 May 2009
• Expression of metallothionein mRNAs on mouse cerebellum microglia cells by thimerosal and its metabolites. 17 Apr 2009
• [Studies on dynamic change of total ginkgolic acids in Ginkgo biloba leaves of different aged trees and different collecting seasons] 30 Mar 2009
• Differential in vitro inhibition of polyphenoloxidase from a wild edible mushroom Lactarius salmonicolor. 30 Mar 2009
• Bacterial consortium proteomics under 4-chlorosalicylate carbon-limiting conditions. 30 Mar 2009
• Ginkgolic acid inhibits protein SUMOylation by blocking formation of the E1-SUMO intermediate. 25 Feb 2009
• Purification and cDNA cloning of a wound inducible glucosyltransferase active toward 12-hydroxy jasmonic acid. 19 Feb 2009
• Ancient horizontal gene transfer from bacteria enhances biosynthetic capabilities of fungi. 10 Feb 2009
• Salirasib (farnesyl thiosalicylic acid) for brain tumor treatment: a convection-enhanced drug delivery study in rats. 30 Oct 2008
• Contribution of salicylic acid glucosyltransferase, OsSGT1, to chemically induced disease resistance in rice plants. 24 Sep 2008
• Structure of aldehyde reductase in ternary complex with coenzyme and the potent 20alpha-hydroxysteroid dehydrogenase inhibitor 3,5-dichlorosalicylic acid: implications for inhibitor binding and selectivity. 26 Aug 2008
• Expression of concern. Jun 2008
• Community-based degradation of 4-chorosalicylate tracked on the single cell level. 24 May 2008
• Production of the polyketide 6-MSA in yeast engineered for increased malonyl-CoA supply. 8 May 2008
• Exogenous spermidine, arsenic and beta-aminobutyric acid modulate tobacco resistance to tobacco mosaic virus, and affect local and systemic glucosylsalicylic acid levels and arginine decarboxylase gene expression in tobacco leaves. 4 May 2008
• Two angular dioxygenases contribute to the metabolic versatility of dibenzofuran-degrading Rhodococcus sp. strain HA01. 23 Apr 2008
• Identification and characterization of (1R,6R)-2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase in the menaquinone biosynthesis of Escherichia coli. 18 Feb 2008

See a longer list of these articles.

Technical information about 'Salicylic Acids'

Definition: Derivatives and salts of SALICYLIC ACID.

Registry Number: 0

Descriptor UI: D012461

Alternative terms: Salicylic Acids; Acids, Salicylic;

Allowable Qualifiers: administration & dosage; adverse effects; analysis; antagonists & inhibitors; blood; cerebrospinal fluid; chemical synthesis; classification; diagnostic use; economics; history; immunology; isolation & purification; metabolism; pharmacokinetics; pharmacology; poisoning; radiation effects; standards; supply & distribution; therapeutic use; toxicity; urine; chemistry; contraindications; agonists;

Tree Number: D02.241.223.100.380.800; D02.241.511.390.700; D02.755.410.700;

Online Note: use SALICYLIC ACIDS to search SALICYLIC ACID 1966-74

History Note: 75; was SALICYLIC ACID 1963-74

Technical Notes: SALICYLIC ACID is also available