Schizophrenia - Genetics
Research News and Information

Saturday, November 21, 2009

Mice mutant for genes associated with schizophrenia: common phenotype or distinct endophenotypes?

5 Dec 2009 Schizophrenia is a complex neuropsychiatric disorder whose etiology involves a mixture of genetic and environmental factors. By virtue of this complexity, schizophrenia is a field of research in which a number of key technologies converge: in ... Read more...

From age correction to genome-wide association.

30 Oct 2009 OBJECTIVE: Eric Strömgren was one of the pioneers of psychiatric genetics and family studies. There has now been an explosion of interest in this field and research progress, including linkage and association studies, whole genome genotyping, copy ... Read more...

Altered effect of dopamine transporter 3'UTR VNTR genotype on prefrontal and striatal function in schizophrenia.

30 Oct 2009 CONTEXT: The dopamine transporter plays a key role in the regulation of central dopaminergic transmission, which modulates cognitive processing. Disrupted dopamine function and impaired executive processing are robust features of schizophrenia. ... Read more...

Latest indexed articles for 'Schizophrenia - Genetics'

These are the very latest articles for this heading:

• Mice mutant for genes associated with schizophrenia: common phenotype or distinct endophenotypes? 5 Dec 2009
• From age correction to genome-wide association. 30 Oct 2009
• Altered effect of dopamine transporter 3'UTR VNTR genotype on prefrontal and striatal function in schizophrenia. 30 Oct 2009
• Schizophrenia: the "BLOC" may be in the endosomes. 18 Oct 2009
• Human genetics: Hit or miss? 6 Oct 2009
• The association of olanzapine-induced weight gain with peroxisome proliferator-activated receptor-gamma2 Pro12Ala polymorphism in patients with schizophrenia. 29 Sep 2009
• A reverse-translational study of dysfunctional exploration in psychiatric disorders: from mice to men. 29 Sep 2009
• Susceptibility locus on chromosome 1q23-25 for a schizophrenia subtype resembling deficit schizophrenia identified by latent class analysis. 29 Sep 2009
• Influence of NOS1 on verbal intelligence and working memory in both patients with schizophrenia and healthy control subjects. 29 Sep 2009
• NMDA receptor phosphorylation at a site affected in schizophrenia controls synaptic and behavioral plasticity. 21 Sep 2009
• The P300 as a possible endophenotype for schizophrenia and bipolar disorder: Evidence from twin and patient studies. 9 Sep 2009
• DISC1 splice variants are upregulated in schizophrenia and associated with risk polymorphisms. 31 Aug 2009
• Association between COMT gene and Chinese male schizophrenic patients with violent behavior. 30 Aug 2009
• Family-based association study of SELENBP1 in schizophrenia. 30 Aug 2009
• Disparate diseases due to copycat copy number variations. 30 Aug 2009
• Recurrent rearrangements in synaptic and neurodevelopmental genes and shared biologic pathways in schizophrenia, autism, and mental retardation. 30 Aug 2009
• Neurexin 1 (NRXN1) deletions in schizophrenia. 10 Aug 2009
• No association of the rs4646396 SNP in the PEMT locus with schizophrenia in a Chinese case-control sample. Aug 2009
• Mutation screening of the glutamate cysteine ligase modifier (GCLM) gene in patients with schizophrenia. 30 Jul 2009
• A variant in the reelin gene increases the risk of schizophrenia and schizoaffective disorder but not bipolar disorder. 30 Jul 2009

See a longer list of these articles.

Technical information about 'Schizophrenia'

Definition: A severe emotional disorder of psychotic depth characteristically marked by a retreat from reality with delusion formation, HALLUCINATIONS, emotional disharmony, and regressive behavior.

Descriptor UI: D012559

Alternative terms: Schizophrenia; Schizophrenias; Dementia Praecox; Schizophrenic Disorders; Disorder, Schizophrenic; Disorders, Schizophrenic; Schizophrenic Disorder;

Allowable Qualifiers: blood; cerebrospinal fluid; chemically induced; classification; complications; diagnosis; diet therapy; drug therapy; economics; enzymology; ethnology; etiology; genetics; history; immunology; metabolism; microbiology; mortality; nursing; epidemiology; parasitology; pathology; physiopathology; prevention & control; radiography; radionuclide imaging; rehabilitation; surgery; therapy; urine; ultrasonography; virology;

Tree Number: F03.700.750;

Technical Notes: general or unspecified; prefer specifics