Second Messenger Systems - Physiology
Research News and Information

Monday, November 23, 2009

Role of p38 MAPK pathway in induction of iNOS expression in neutrophils and peripheral blood mononuclear cells in patients with squamous cell carcinoma of the oral cavity.

30 Oct 2009 PURPOSE: The aim of the present study was to assess the role of the p38 mitogen-activated protein kinase (MAPK) pathway in the induction of inducible nitric oxide synthase (iNOS) expression and the production of NO by neutrophils (polymorphonuclear ... Read more...

Neurotransmitters, receptors, and second messengers galore in 40 years.

12 Oct 2009 The past four decades have witnessed extraordinary advances in the molecular understanding of neurotransmitters, their receptors, and second messengers. This essay highlights a selected group of particular notable discoveries, emphasizing seminal ... Read more...

Second messenger signaling: multiple receptors for NAADP.

12 Jul 2009 The second messenger NAADP appears to have an essential role as a universal trigger of Ca(2+) signaling. Following on from previously published NAADP receptor candidates, recent work now describes the identification of a novel NAADP-sensitive Ca(2+) ... Read more...

Latest indexed articles for 'Second Messenger Systems - Physiology'

These are the very latest articles for this heading:

• Role of p38 MAPK pathway in induction of iNOS expression in neutrophils and peripheral blood mononuclear cells in patients with squamous cell carcinoma of the oral cavity. 30 Oct 2009
• Neurotransmitters, receptors, and second messengers galore in 40 years. 12 Oct 2009
• Second messenger signaling: multiple receptors for NAADP. 12 Jul 2009
• An unexpected effect of 5-MCA-NAT in chick retinal development. 7 Jul 2009
• Adenylate cyclase regulates elongation of mammalian primary cilia. 30 Jun 2009
• Somatic cAMP signaling regulates MSP-dependent oocyte growth and meiotic maturation in C. elegans. 29 Jun 2009
• cAMP signaling in Mycobacterium tuberculosis. 30 May 2009
• Lipoxygenase-mediated pro-radical effect of melatonin via stimulation of arachidonic acid metabolism. 17 May 2009
• Extracts from salivary glands stimulate aggression and inositol-1, 4, 5-triphosphate (IP3) production in the vomeronasal organ of mice. 16 May 2009
• Cellular prion protein coupling to TACE-dependent TNF-alpha shedding controls neurotransmitter catabolism in neuronal cells. 16 May 2009
• An Ang1-Tie2-PI3K axis in neural progenitor cells initiates survival responses against oxygen and glucose deprivation. 3 May 2009
• PrPc activation induces neurite outgrowth and differentiation in PC12 cells: role for caveolin-1 in the signal transduction pathway. 25 Apr 2009
• D3 dopamine receptor regulation of ETB receptors in renal proximal tubule cells from WKY and SHRs. 21 Apr 2009
• Inhibitory effect of ZPDC glycoprotein on the expression of inflammation-related cytokines through p38 MAP kinase and JNK in lipopolysaccharide-stimulated RAW 264.7 cells. 30 Mar 2009
• Imaging cytoplasmic cAMP in mouse brainstem neurons. 25 Mar 2009
• Bacterial nucleotide-based second messengers. 19 Mar 2009
• Activation of ROS/NF-kappaB and Ca2+/CaM kinase II are necessary for VCAM-1 induction in IL-1beta-treated human tracheal smooth muscle cells. 8 Mar 2009
• Pretreatment with a single estradiol-17beta bolus activates cyclic-AMP response element binding protein and protects CA1 neurons against global cerebral ischemia. 7 Mar 2009
• Some scientific reflections on possible mechanisms of general anaesthesia. 27 Feb 2009
• Gene regulation by voltage-dependent calcium channels. 25 Feb 2009

See a longer list of these articles.

Technical information about 'Second Messenger Systems'

Definition: Systems in which an intracellular signal is generated in response to an intercellular primary messenger such as a hormone or neurotransmitter. They are intermediate signals in cellular processes such as metabolism, secretion, contraction, phototransduction, and cell growth. Examples of second messenger systems are the adenyl cyclase-cyclic AMP system, the phosphatidylinositol diphosphate-inositol triphosphate system, and the cyclic GMP system.

Descriptor UI: D015290

Alternative terms: Second Messenger Systems; Second Messenger System; System, Second Messenger; Systems, Second Messenger; Second Messengers; Messenger, Second; Messengers, Second; Second Messenger; Intracellular Second Messengers; Intracellular Second Messenger; Messengers, Intracellular Second; Second Messenger, Intracellular; Second Messengers, Intracellular;

Allowable Qualifiers: drug effects; genetics; immunology; physiology; radiation effects; ethics;

Tree Number: G02.111.087.800.800; G02.149.115.800.800; G04.299.880.800;

History Note: 89

Technical Notes: a metab concept; IM; coord with substance acting as the second messenger (IM) with /physiol or /antag as applicable; DF: SECOND MESSENGERS