Second Messenger Systems
Research News and Information

Sunday, November 22, 2009

Role of p38 MAPK pathway in induction of iNOS expression in neutrophils and peripheral blood mononuclear cells in patients with squamous cell carcinoma of the oral cavity.

30 Oct 2009 PURPOSE: The aim of the present study was to assess the role of the p38 mitogen-activated protein kinase (MAPK) pathway in the induction of inducible nitric oxide synthase (iNOS) expression and the production of NO by neutrophils (polymorphonuclear ... Read more...

Neurotransmitters, receptors, and second messengers galore in 40 years.

12 Oct 2009 The past four decades have witnessed extraordinary advances in the molecular understanding of neurotransmitters, their receptors, and second messengers. This essay highlights a selected group of particular notable discoveries, emphasizing seminal ... Read more...

Dynamic visualization of signal transduction in living cells: from second messengers to kinases.

30 Aug 2009 The study of signal transduction, or the highly regulated series of biochemical events which allow a cell to convert a given stimulus into a functional response, has seen a paradigm shift with a recent explosion in the number of genetically encoded ... Read more...

Latest indexed articles for 'Second Messenger Systems'

These are the very latest articles for this heading:

• Role of p38 MAPK pathway in induction of iNOS expression in neutrophils and peripheral blood mononuclear cells in patients with squamous cell carcinoma of the oral cavity. 30 Oct 2009
• Neurotransmitters, receptors, and second messengers galore in 40 years. 12 Oct 2009
• Dynamic visualization of signal transduction in living cells: from second messengers to kinases. 30 Aug 2009
• Pharmacological stimulation of soluble guanylate cyclase modulates hypoxia-inducible factor-1alpha in rat heart. 12 Aug 2009
• A host type I interferon response is induced by cytosolic sensing of the bacterial second messenger cyclic-di-GMP. Aug 2009
• Direct inhibition of ERK1/2 phosphorylation as a possible mechanism for the antiproliferative action of 3,4-diOH-PCB3 in the MCF-7 cell line. 16 Jul 2009
• Second messenger signaling: multiple receptors for NAADP. 12 Jul 2009
• Inhibition of renal Na+-ATPase activity by inosine is mediated by A1 receptor-induced inhibition of the cAMP signaling pathway. 10 Jul 2009
• An unexpected effect of 5-MCA-NAT in chick retinal development. 7 Jul 2009
• Adenylate cyclase regulates elongation of mammalian primary cilia. 30 Jun 2009
• Activation of latent transforming growth factor-beta1 by nitric oxide in macrophages: role of soluble guanylate cyclase and MAP kinases. 29 Jun 2009
• Somatic cAMP signaling regulates MSP-dependent oocyte growth and meiotic maturation in C. elegans. 29 Jun 2009
• Connecting quorum sensing, c-di-GMP, pel polysaccharide, and biofilm formation in Pseudomonas aeruginosa through tyrosine phosphatase TpbA (PA3885). 17 Jun 2009
• Suppression of LPS-induced TNF-alpha production in macrophages by cAMP is mediated by PKA-AKAP95-p105. 14 Jun 2009
• Putting on the brakes: cyclic AMP as a multipronged controller of macrophage function. 14 Jun 2009
• Immunolocalization of tumor necrosis factor receptor-associated factor 6 in rat periapical lesions. 30 May 2009
• cAMP signaling in Mycobacterium tuberculosis. 30 May 2009
• In vivo reorganization of the actin cytoskeleton in leaves of Nicotiana tabacum L. transformed with plastin-GFP. Correlation with light-activated chloroplast responses. 27 May 2009
• Lipoxygenase-mediated pro-radical effect of melatonin via stimulation of arachidonic acid metabolism. 17 May 2009
• Extracts from salivary glands stimulate aggression and inositol-1, 4, 5-triphosphate (IP3) production in the vomeronasal organ of mice. 16 May 2009

See a longer list of these articles.

Technical information about 'Second Messenger Systems'

Definition: Systems in which an intracellular signal is generated in response to an intercellular primary messenger such as a hormone or neurotransmitter. They are intermediate signals in cellular processes such as metabolism, secretion, contraction, phototransduction, and cell growth. Examples of second messenger systems are the adenyl cyclase-cyclic AMP system, the phosphatidylinositol diphosphate-inositol triphosphate system, and the cyclic GMP system.

Descriptor UI: D015290

Alternative terms: Second Messenger Systems; Second Messenger System; System, Second Messenger; Systems, Second Messenger; Second Messengers; Messenger, Second; Messengers, Second; Second Messenger; Intracellular Second Messengers; Intracellular Second Messenger; Messengers, Intracellular Second; Second Messenger, Intracellular; Second Messengers, Intracellular;

Allowable Qualifiers: drug effects; genetics; immunology; physiology; radiation effects; ethics;

Tree Number: G02.111.087.800.800; G02.149.115.800.800; G04.299.880.800;

History Note: 89

Technical Notes: a metab concept; IM; coord with substance acting as the second messenger (IM) with /physiol or /antag as applicable; DF: SECOND MESSENGERS