Selenium - Therapeutic use
Research News and Information

Sunday, November 22, 2009

Methylselenol, a selenium metabolite, induces cell cycle arrest in G1 phase and apoptosis via the extracellular-regulated kinase 1/2 pathway and other cancer signaling genes.

20 Jul 2009 Methylselenol has been hypothesized to be a critical selenium (Se) metabolite for anticancer activity in vivo, and our previous study demonstrated that submicromolar methylselenol generated by incubating methionase with seleno-l-methionine inhibits ... Read more...

Selenium supplementation in HIV-infected patients: is there any potential clinical benefit?

29 Jun 2009 In HIV-infected patients undergoing antiretroviral therapy, the question of whether selenium supplementation has any therapeutic benefit is still open. With recent popular coverage of this issue, many patients have considered using selenium. ... Read more...

Cancer prevention: from 1727 to milestones of the past 100 years.

31 May 2009 The rich, multidisciplinary history of cancer prevention recounted here begins with surgical and workplace recommendations of the 1700s and ends with 2009 results of the enormous (35,535 men) Selenium and Vitamin E [prostate] Cancer Prevention Trial ... Read more...

Latest indexed articles for 'Selenium - Therapeutic use'

These are the very latest articles for this heading:

• Should we be considering selenium in glaucoma? 30 Aug 2009
• Re: Selenium and vitamin E: interesting biology and dashed hope. 25 Aug 2009
• Methylselenol, a selenium metabolite, induces cell cycle arrest in G1 phase and apoptosis via the extracellular-regulated kinase 1/2 pathway and other cancer signaling genes. 20 Jul 2009
• Selenium supplementation in HIV-infected patients: is there any potential clinical benefit? 29 Jun 2009
• Selenium, genetic variation, and prostate cancer risk: epidemiology reflects back on selenium and vitamin E cancer prevention trial. 13 Jun 2009
• Cancer prevention: from 1727 to milestones of the past 100 years. 31 May 2009
• Antioxidant supplementation and cancer prevention. 11 May 2009
• Selenium and vitamin E supplementation for cancer prevention. 11 May 2009
• Antioxidant supplementation and cancer prevention. 11 May 2009
• Selenium and vitamin E supplementation for cancer prevention. 11 May 2009
• Chemoprevention of prostate cancer: what can be recommended to patients? 29 Apr 2009
• Ingredients for functional drinks in neurodegenerative diseases: a review. 29 Apr 2009
• A combination of micronutrients is beneficial in reducing the incidence of prostate cancer and increasing survival in the Lady transgenic model. 26 Apr 2009
• Rationale and design of the pediatric critical illness stress-induced immune suppression (CRISIS) prevention trial. 12 Apr 2009
• Prostate cancer: a serious disease suitable for prevention. 30 Mar 2009
• Selenium as an essential micronutrient: roles in cell cycle and apoptosis. 21 Mar 2009
• Antioxidants: SELECTed out? 27 Feb 2009
• Selenium supplementation fails to correct the selenoprotein synthesis defect in subjects with SBP2 gene mutations. 27 Feb 2009
• Spectacular reduction in the mortality of acutely injured patients by the administration of vitamins C and E and selenium. 17 Feb 2009
• Does early administration of selenium improve neurological outcome after cardiac arrest? 30 Jan 2009

See a longer list of these articles.

Technical information about 'Selenium'

Definition: An element with the atomic symbol Se, atomic number 34, and atomic weight 78.96. It is an essential micronutrient for mammals and other animals but is toxic in large amounts. Selenium protects intracellular structures against oxidative damage. It is an essential component of GLUTATHIONE PEROXIDASE.

Registry Number: 7782-49-2

Descriptor UI: D012643

Alternative terms: Selenium;

Related Mesh Headings: Selenium Radioisotopes;

Allowable Qualifiers: administration & dosage; adverse effects; analysis; antagonists & inhibitors; blood; cerebrospinal fluid; classification; deficiency; diagnostic use; economics; history; immunology; isolation & purification; metabolism; pharmacokinetics; pharmacology; physiology; poisoning; radiation effects; standards; supply & distribution; therapeutic use; toxicity; urine; chemistry; contraindications; agonists;

Pharmacological Action: Trace Elements; Antioxidants;

Tree Number: D01.268.185.850; D01.578.700;

Technical Notes: Se-80; Se-74, 76-78, 82 = SELENIUM (IM) + ISOTOPES (NIM); Se-70-73, 75, 79, 81, 83-85 = SELENIUM RADIOISOTOPES (IM)