Septum of Brain - Pathology
Research News and Information

Friday, March 19, 2010

Cortical deactivation induced by subcortical network dysfunction in limbic seizures.

12 Oct 2009 Normal human consciousness may be impaired by two possible routes: direct reduced function in widespread cortical regions or indirect disruption of subcortical activating systems. The route through which temporal lobe limbic seizures impair ... Read more...

Interleukin-2 deficiency-induced T cell autoimmunity in the mouse brain.

8 Jul 2009 Interleukin-2 (IL-2) has been implicated in the pathogenesis of neurodevelopmental and neurodegenerative disorders. Studies from our lab have shown that adult IL-2 knockout (KO) mice exhibit septohippocampal pathology and related behavioral ... Read more...

Early Tau pathology involving the septo-hippocampal pathway in a Tau transgenic model: relevance to Alzheimer's disease.

30 Mar 2009 Alzheimer's disease is a neurodegenerative disorder characterized by amyloid deposits and neurofibrillary tangles. Cholinergic dysfunction is also a main pathological feature of the disease. Nevertheless, the links between cholinergic dysfunction ... Read more...

Latest indexed articles for 'Septum of Brain - Pathology'

These are the very latest articles for this heading:

• Cortical deactivation induced by subcortical network dysfunction in limbic seizures. 12 Oct 2009
• Interleukin-2 deficiency-induced T cell autoimmunity in the mouse brain. 8 Jul 2009
• Early Tau pathology involving the septo-hippocampal pathway in a Tau transgenic model: relevance to Alzheimer's disease. 30 Mar 2009
• Theta activity of septal neurons during different epileptic phases: the same frequency but different significance? 8 Jan 2009
• Memory loss resulting from fornix and septal damage: impaired supra-span recall but preserved recognition over a 24-hour delay. 30 Aug 2008
• alpha(1)-Adrenoceptors in the lateral septal area modulate food intake behaviour in rats. 19 Jul 2008
• Selective cholinergic lesions in the rat nucleus basalis magnocellularis with limited damage in the medial septum specifically alter attention performance in the five-choice serial reaction time task. 3 Feb 2008
• Subsequent exposure to the choline uptake enhancer MKC-231 antagonizes phencyclidine-induced behavioral deficits and reduction in septal cholinergic neurons in rats. 28 Apr 2007
• Volumetric analysis of septal region in schizophrenia and affective disorder. 14 Dec 2006
• Septal GABAergic neurons are selectively vulnerable to pilocarpine-induced status epilepticus and chronic spontaneous seizures. 22 Aug 2006
• [Septal fibromuscular dysplasia of the internal carotid artery, associated to systemic lupus erythematosus] 30 Jul 2006
• Reorganization of CA3 area of the mouse hippocampus after pilocarpine induced temporal lobe epilepsy with special reference to the CA3-septum pathway. 30 Jan 2006
• Septal innervation regulates the function of alpha7 nicotinic receptors in CA1 hippocampal interneurons. 29 Sep 2005
• Mapping and reconstruction of domoic acid-induced neurodegeneration in the mouse brain. 14 Aug 2005
• Effects of 5-HT1A-receptor agonist, 8-OH-DPAT, and GABAB-receptor agonist, baclofen, on lordosis in female rats with lesions in either the dorsal raphe nucleus or septum. 31 Jul 2005
• IL-2 deficiency results in altered septal and hippocampal cytoarchitecture: relation to development and neurotrophins. 21 Dec 2004
• No facilitation of amphetamine- or cocaine-induced hyperactivity in adult rats after various 192 IgG-saporin lesions in the basal forebrain. 15 Dec 2004
• Heterogeneity between hippocampal and septal astroglia as a contributing factor to differential in vivo AMPA excitotoxicity. 30 Jul 2004
• Polyethylenimine-mediated NGF gene delivery protects transected septal cholinergic neurons. 20 May 2004
• Abnormal hippocampal axon bundling in EphB receptor mutant mice. 8 Mar 2004

See a longer list of these articles.

Technical information about 'Septum of Brain'

Definition: Gray matter structures of the telencephalon and limbic system in the brain, but containing widely varying definitions among authors. Included here is the cortical septal area, subcortical SEPTAL NUCLEI, and the SEPTUM PELLUCIDUM. Many authorities consider the septal region to be made up of the septal area and the septal nuclei, but excluding the septum pellucidum. (Anthoney, Neuroanatomy and the Neurologic Exam, 1994, pp485-489; NeuroNames, http://rprcsgi.rprc.washington.edu/neuronames/index.html (November 18, 1998)).

Descriptor UI: D020665

Alternative terms: Septum of Brain; Brain Septum; Brain Septums; Septal Region; Region, Septal; Septal Area; Area, Septal;

Allowable Qualifiers: abnormalities; anatomy & histology; blood supply; cytology; drug effects; embryology; enzymology; growth & development; immunology; injuries; metabolism; microbiology; parasitology; pathology; physiology; physiopathology; radiation effects; radiography; radionuclide imaging; secretion; surgery; transplantation; ultrastructure; ultrasonography; chemistry; virology;

Tree Number: A08.186.211.464.750; A08.186.211.730.885.750;

History Note: 2000

Technical Notes: SEPTUM PELLUCIDUM is also available