Sequence Alignment - Methods
Research News and Information

Monday, November 23, 2009

Sense from sequence reads: methods for alignment and assembly.

30 Oct 2009 The most important first step in understanding next-generation sequencing data is the initial alignment or assembly that determines whether an experiment has succeeded and provides a first glimpse into the results. In parallel with the growth of new ... Read more...

Computation for ChIP-seq and RNA-seq studies.

30 Oct 2009 Genome-wide measurements of protein-DNA interactions and transcriptomes are increasingly done by deep DNA sequencing methods (ChIP-seq and RNA-seq). The power and richness of these counting-based measurements comes at the cost of routinely handling ... Read more...

Next-generation gap.

30 Oct 2009 There is a growing gap between the generation of massively parallel sequencing output and the ability to process and analyze the resulting data. New users are left to navigate a bewildering maze of base calling, alignment, assembly and analysis ... Read more...

Latest indexed articles for 'Sequence Alignment - Methods'

These are the very latest articles for this heading:

• Sense from sequence reads: methods for alignment and assembly. 30 Oct 2009
• Computation for ChIP-seq and RNA-seq studies. 30 Oct 2009
• Next-generation gap. 30 Oct 2009
• A robust method for searching the smallest set of smallest rings with a path-included distance matrix. 22 Sep 2009
• An introduction to sequence similarity ("homology") searching. 30 Aug 2009
• Graphical models of protein-protein interaction specificity from correlated mutations and interaction data. 30 Aug 2009
• PAVE: program for assembling and viewing ESTs. 24 Aug 2009
• CSA: an efficient algorithm to improve circular DNA multiple alignment. 21 Jul 2009
• The RNA structure alignment ontology. 19 Jul 2009
• Iterative refinement of structure-based sequence alignments by Seed Extension. 7 Jul 2009
• RBT-GA: a novel metaheuristic for solving the Multiple Sequence Alignment problem. 5 Jul 2009
• Di-codon usage for classification of genes. Jul 2009
• Ensemble approach to predict specificity determinants: benchmarking and validation. 30 Jun 2009
• Representative transcript sets for evaluating a translational initiation sites predictor. 30 Jun 2009
• GR-Aligner: an algorithm for aligning pairwise genomic sequences containing rearrangement events. 17 Jun 2009
• Rapid and accurate large-scale coestimation of sequence alignments and phylogenetic trees. 17 Jun 2009
• RegExpBlasting (REB), a Regular Expression Blasting algorithm based on multiply aligned sequences. 14 Jun 2009
• Towards accurate human promoter recognition: a review of currently used sequence features and classification methods. 14 Jun 2009
• Domain-oriented edge-based alignment of protein interaction networks. 13 Jun 2009
• Predictions of RNA secondary structure by combining homologous sequence information. 13 Jun 2009

See a longer list of these articles.

Technical information about 'Sequence Alignment'

Definition: The arrangement of two or more amino acid or base sequences from an organism or organisms in such a way as to align areas of the sequences sharing common properties. The degree of relatedness or homology between the sequences is predicted computationally or statistically based on weights assigned to the elements aligned between the sequences. This in turn can serve as a potential indicator of the genetic relatedness between the organisms.

Descriptor UI: D016415

Alternative terms: Sequence Alignment; Alignment, Sequence; Alignments, Sequence; Sequence Alignments; Determination, Sequence Homology; Determinations, Sequence Homology; Sequence Homology Determinations; Sequence Homology Determination;

Allowable Qualifiers: adverse effects; classification; economics; history; instrumentation; methods; mortality; nursing; psychology; standards; trends; utilization; veterinary; statistics & numerical data; contraindications;

Tree Number: E05.393.751;

History Note: 91

Technical Notes: DF: SEQ ALIGNMENT