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Sequence Alignment
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Definition of 'Sequence Alignment'

The arrangement of two or more amino acid or base sequences from an organism or organisms in such a way as to align areas of the sequences sharing common properties. The degree of relatedness or homology between the sequences is predicted computationally or statistically based on weights assigned to the elements aligned between the sequences. This in turn can serve as a potential indicator of the genetic relatedness between the organisms.

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Saturday, November 21, 2009

From consensus structure prediction to RNA gene finding.

30 Oct 2009 Reliable structure prediction is a prerequisite for most types of bioinformatical analysis of RNA. Since the accuracy of structure prediction from single sequences is limited, one often resorts to computing the consensus structure for a set of ... Read more...


Muscle FBPase is targeted to nucleus by its 203KKKGK207 sequence.

30 Oct 2009 It has been recently found that muscle fructose 1,6-bisphosphatase (FBPase) is actively transported into cells' nuclei. Results of an analysis in silico of muscle FBPase structure gave rise to a hypothesis that sequence (203)KKKGK(207) is ... Read more...


The Rho GTPase inactivation domain in Vibrio cholerae MARTX toxin has a circularly permuted papain-like thiol protease fold.

30 Oct 2009 A Rho GTPase inactivation domain (RID) has been discovered in the multifunctional, autoprocessing RTX toxin RtxA from Vibrio cholerae. The RID domain causes actin depolymerization and rounding of host cells through inactivation of the small Rho ... Read more...

 

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Technical information about 'Sequence Alignment'

Definition: The arrangement of two or more amino acid or base sequences from an organism or organisms in such a way as to align areas of the sequences sharing common properties. The degree of relatedness or homology between the sequences is predicted computationally or statistically based on weights assigned to the elements aligned between the sequences. This in turn can serve as a potential indicator of the genetic relatedness between the organisms.

Descriptor UI: D016415

Alternative terms: Sequence Alignment; Alignment, Sequence; Alignments, Sequence; Sequence Alignments; Determination, Sequence Homology; Determinations, Sequence Homology; Sequence Homology Determinations; Sequence Homology Determination;

Allowable Qualifiers: adverse effects; classification; economics; history; instrumentation; methods; mortality; nursing; psychology; standards; trends; utilization; veterinary; statistics & numerical data; contraindications;

Tree Number: E05.393.751;

History Note: 91

Technical Notes: DF: SEQ ALIGNMENT

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