Serine Endopeptidases - Analysis
Research News and Information

Monday, November 23, 2009

Bodo sp., a free-living flagellate, expresses divergent proteolytic activities from the closely related parasitic trypanosomatids.

30 Aug 2009 We report the characterization of cell-associated and extracellular peptidases of Bodo sp., a free-living flagellate of the Bodonidae family, order Kinetoplastida, which is considered ancestral to the trypanosomatids. This bodonid isolate is ... Read more...

Aberrant ENaC activation in Dahl salt-sensitive rats.

30 Jul 2009 BACKGROUND: The epithelial sodium channel (ENaC) plays an important role in the regulation of blood pressure by modulating Na reabsorption in the kidney. Dahl salt-sensitive rats on high-salt diet develop severe hypertension, and high-salt diet has ... Read more...

Use of IHC and newly designed matriptase inhibitors to elucidate the role of matriptase in pancreatic ductal adenocarcinoma.

30 Jul 2009 Matriptase, also known as MT-SP1, is a type II transmembrane serine protease strongly implicated in both the development and progression of a variety of epithelial cancers. Evidence comes from studies of its expression in human cancers and from ... Read more...

Latest indexed articles for 'Serine Endopeptidases - Analysis'

These are the very latest articles for this heading:

• Bodo sp., a free-living flagellate, expresses divergent proteolytic activities from the closely related parasitic trypanosomatids. 30 Aug 2009
• Aberrant ENaC activation in Dahl salt-sensitive rats. 30 Jul 2009
• Use of IHC and newly designed matriptase inhibitors to elucidate the role of matriptase in pancreatic ductal adenocarcinoma. 30 Jul 2009
• Identification of transplantable dopamine neuron precursors at different stages of midbrain neurogenesis. 21 Jun 2009
• Exploring the venom proteome of the western diamondback rattlesnake, Crotalus atrox, via snake venomics and combinatorial peptide ligand library approaches. 30 May 2009
• Expression of human HtrA1, HtrA2, HtrA3 and TGF-beta1 genes in primary endometrial cancer. 30 May 2009
• Development of a liquid chromatography-based screening methodology for proteolytic enzyme activity. 23 Mar 2009
• Diversity of serine hydrolase activities of unchallenged and botrytis-infected Arabidopsis thaliana. 9 Jan 2009
• [Merkel cell carcinoma--immunohistochemical study in a group of 11 patients] 30 Dec 2008
• Delineating protease functions during cancer development. 30 Dec 2008
• Current state and future applications of active targeting in malignancies using superparamagnetic iron oxide nanoparticles. 30 Dec 2008
• Protein expression of matriptase and its cognate inhibitor HAI-1 in human prostate cancer: a tissue microarray and automated quantitative analysis. 30 Dec 2008
• Hepsin colocalizes with desmosomes and induces progression of ovarian cancer in a mouse model. 30 Oct 2008
• Characterization of a serine proteinase mediating encystation of Acanthamoeba. 30 Jul 2008
• Significance of thrombomodulin release from gingival epithelial cells in periodontitis patients. 30 Jul 2008
• Elevated expression of serine protease HtrA1 in preeclampsia and its role in trophoblast cell migration and invasion. 27 Jul 2008
• Distribution of prolyl oligopeptidase in the mouse whole-body sections and peripheral tissues. 9 Jul 2008
• Purification from human milk of matriptase complexes with secreted serpins: mechanism for inhibition of matriptase other than HAI-1. 9 Jun 2008
• The androgen-regulated type II serine protease TMPRSS2 is differentially expressed and mislocalized in prostate adenocarcinoma. 30 May 2008
• Detection of the TMPRSS2-ETS fusion gene in prostate carcinomas: retrospective analysis of 55 formalin-fixed and paraffin-embedded samples with clinical data. 29 Apr 2008

See a longer list of these articles.

Technical information about 'Serine Endopeptidases'

Definition: Any member of the group of ENDOPEPTIDASES containing at the active site a serine residue involved in catalysis. EC 3.4.21.

Registry Number: EC 3.4.21.-

Descriptor UI: D012697

Alternative terms: Serine Endopeptidases; Endopeptidases, Serine; Serine Proteinases; Proteinases, Serine; Serine Protein Hydrolases; Hydrolases, Serine Protein; Protein Hydrolases, Serine; Serine Proteinase; Proteinase, Serine; Serine Protease; Protease, Serine; Serine Proteases; Proteases, Serine;

Allowable Qualifiers: administration & dosage; adverse effects; analysis; biosynthesis; blood; cerebrospinal fluid; chemical synthesis; classification; deficiency; diagnostic use; drug effects; economics; genetics; history; immunology; isolation & purification; metabolism; pharmacokinetics; pharmacology; physiology; poisoning; radiation effects; secretion; standards; supply & distribution; therapeutic use; toxicity; ultrastructure; urine; chemistry; contraindications;

Tree Number: D08.811.277.656.300.760;

History Note: 2000(1988)