Serine Endopeptidases - Metabolism
Research News and Information

Saturday, November 21, 2009

C-terminal region-dependent change of antibody-binding to the Eighth Reelin repeat reflects the signaling activity of Reelin.

30 Oct 2009 Reelin is a secreted glycoprotein that plays pivotal roles in the development and function of the brain, but how it activates downstream intracellular signaling is not fully understood. We have recently reported that the highly conserved C-terminal ... Read more...

Expression pattern alterations of the serine protease HtrA1 in normal human placental tissues and in gestational trophoblastic diseases.

29 Sep 2009 HtrA1 is a secreted protein which behaves as a molecular chaperone at low temperatures and as a serine protease at high temperatures. When the placenta escapes the normal growth control mechanisms, which are present during normal pregnancy, it may ... Read more...

A role for nuclear translocation of tripeptidyl-peptidase II in reactive oxygen species-dependent DNA damage responses.

8 Sep 2009 Responses to DNA damage are influenced by cellular metabolism through the continuous production of reactive oxygen species (ROS), of which most are by-products of mitochondrial respiration. ROS have a strong influence on signaling pathways during ... Read more...

Latest indexed articles for 'Serine Endopeptidases - Metabolism'

These are the very latest articles for this heading:

• C-terminal region-dependent change of antibody-binding to the Eighth Reelin repeat reflects the signaling activity of Reelin. 30 Oct 2009
• Expression pattern alterations of the serine protease HtrA1 in normal human placental tissues and in gestational trophoblastic diseases. 29 Sep 2009
• A new twist on a classic paradigm: illumination of a genetic switch in Vibrio cholerae phage CTX Phi. 9 Sep 2009
• A role for nuclear translocation of tripeptidyl-peptidase II in reactive oxygen species-dependent DNA damage responses. 8 Sep 2009
• Complement component C2, inhibiting a latent serine protease in the classical pathway of complement activation. 6 Sep 2009
• Accumulation of reelin-positive plaques is accompanied by a decline in basal forebrain projection neurons during normal aging. 2 Sep 2009
• Roles of periplasmic chaperone proteins in the biogenesis of serine protease autotransporters of Enterobacteriaceae. 2 Sep 2009
• Modelling of tumour--host coexistence In vitro in the presence of serine protease inhibitors. 30 Aug 2009
• ADAM-8 isolated from human osteoarthritic chondrocytes cleaves fibronectin at Ala(271). 30 Aug 2009
• The emerging roles of serine protease cascades in the epidermis. 29 Aug 2009
• Critical role of mast cell chymase in mouse abdominal aortic aneurysm formation. 29 Aug 2009
• Chemokine degradation by the Group A streptococcal serine proteinase ScpC can be reconstituted in vitro and requires two separate domains. 25 Aug 2009
• Downregulation of functional Reelin receptors in projection neurons implies that primary Reelin action occurs at early/premigratory stages. 24 Aug 2009
• Dynamics and function of compact nucleosome arrays. 21 Aug 2009
• Protein sectors: evolutionary units of three-dimensional structure. 19 Aug 2009
• Reddish, scaly, and itchy: how proteases and their inhibitors contribute to inflammatory skin diseases. 16 Aug 2009
• Structural determinants of autoproteolysis of the Haemophilus influenzae Hap autotransporter. 15 Aug 2009
• A mechanism for cell cycle regulation of sporulation initiation in Bacillus subtilis. 13 Aug 2009
• Reelin and apoE actions on signal transduction, synaptic function and memory formation. 11 Aug 2009
• Vibrio cholerae LexA coordinates CTX prophage gene expression. 5 Aug 2009

See a longer list of these articles.

Technical information about 'Serine Endopeptidases'

Definition: Any member of the group of ENDOPEPTIDASES containing at the active site a serine residue involved in catalysis. EC 3.4.21.

Registry Number: EC 3.4.21.-

Descriptor UI: D012697

Alternative terms: Serine Endopeptidases; Endopeptidases, Serine; Serine Proteinases; Proteinases, Serine; Serine Protein Hydrolases; Hydrolases, Serine Protein; Protein Hydrolases, Serine; Serine Proteinase; Proteinase, Serine; Serine Protease; Protease, Serine; Serine Proteases; Proteases, Serine;

Allowable Qualifiers: administration & dosage; adverse effects; analysis; biosynthesis; blood; cerebrospinal fluid; chemical synthesis; classification; deficiency; diagnostic use; drug effects; economics; genetics; history; immunology; isolation & purification; metabolism; pharmacokinetics; pharmacology; physiology; poisoning; radiation effects; secretion; standards; supply & distribution; therapeutic use; toxicity; ultrastructure; urine; chemistry; contraindications;

Tree Number: D08.811.277.656.300.760;

History Note: 2000(1988)