Serine Endopeptidases
Research News and Information

Thursday, November 05, 2009

Expression pattern alterations of the serine protease HtrA1 in normal human placental tissues and in gestational trophoblastic diseases.

29 Sep 2009 HtrA1 is a secreted protein which behaves as a molecular chaperone at low temperatures and as a serine protease at high temperatures. When the placenta escapes the normal growth control mechanisms, which are present during normal pregnancy, it may ... Read more...

Expression, purification, and characterization of pro-phenoloxidase-activating serine protease from Spodoptera litura.

29 Sep 2009 One of the important trigger molecules for innate immunity is a serine protease that activates zymogen phenol oxidase (PPO). Central to wound healing response is the activation of phenol oxidase zymogen. Molecular characterization of phenol oxidase ... Read more...

Anomalous immunogenic properties of serine proteases.

29 Sep 2009 It has previously been shown that a approximately 27 kDa serine protease of Schistosoma mansoni larvae, the cercarial elastase (CE), was a poor immunogen in as much as it failed to induce an antibody response. The CE has a critical role in enabling ... Read more...

Latest indexed articles for 'Serine Endopeptidases'

These are the very latest articles for this heading:

• Expression pattern alterations of the serine protease HtrA1 in normal human placental tissues and in gestational trophoblastic diseases. 29 Sep 2009
• Expression, purification, and characterization of pro-phenoloxidase-activating serine protease from Spodoptera litura. 29 Sep 2009
• Anomalous immunogenic properties of serine proteases. 29 Sep 2009
• Crystallographic analysis of bacterial signal peptidase in ternary complex with arylomycin A2 and a beta-sultam inhibitor. 27 Sep 2009
• Membrane type-1 matrix metalloprotease-independent activation of pro-matrix metalloprotease-2 by proprotein convertases. 21 Sep 2009
• Evolutionary biology. How beach life favors blond mice. 9 Sep 2009
• A role for nuclear translocation of tripeptidyl-peptidase II in reactive oxygen species-dependent DNA damage responses. 8 Sep 2009
• Complement component C2, inhibiting a latent serine protease in the classical pathway of complement activation. 6 Sep 2009
• Bodo sp., a free-living flagellate, expresses divergent proteolytic activities from the closely related parasitic trypanosomatids. 30 Aug 2009
• ADAM-8 isolated from human osteoarthritic chondrocytes cleaves fibronectin at Ala(271). 30 Aug 2009
• The emerging roles of serine protease cascades in the epidermis. 29 Aug 2009
• Critical role of mast cell chymase in mouse abdominal aortic aneurysm formation. 29 Aug 2009
• Chemokine degradation by the Group A streptococcal serine proteinase ScpC can be reconstituted in vitro and requires two separate domains. 25 Aug 2009
• Downregulation of functional Reelin receptors in projection neurons implies that primary Reelin action occurs at early/premigratory stages. 24 Aug 2009
• Dynamics and function of compact nucleosome arrays. 21 Aug 2009
• Protein sectors: evolutionary units of three-dimensional structure. 19 Aug 2009
• Reddish, scaly, and itchy: how proteases and their inhibitors contribute to inflammatory skin diseases. 16 Aug 2009
• A mechanism for cell cycle regulation of sporulation initiation in Bacillus subtilis. 13 Aug 2009
• Flaviviral protease inhibitors identified by fragment-based library docking into a structure generated by molecular dynamics. 11 Aug 2009
• Effects of antibiotics and a proto-oncogene homolog on destruction of protein translocator SecY. 5 Aug 2009

See a longer list of these articles.

Technical information about 'Serine Endopeptidases'

Definition: Any member of the group of ENDOPEPTIDASES containing at the active site a serine residue involved in catalysis. EC 3.4.21.

Registry Number: EC 3.4.21.-

Descriptor UI: D012697

Alternative terms: Serine Endopeptidases; Endopeptidases, Serine; Serine Proteinases; Proteinases, Serine; Serine Protein Hydrolases; Hydrolases, Serine Protein; Protein Hydrolases, Serine; Serine Proteinase; Proteinase, Serine; Serine Protease; Protease, Serine; Serine Proteases; Proteases, Serine;

Allowable Qualifiers: administration & dosage; adverse effects; analysis; biosynthesis; blood; cerebrospinal fluid; chemical synthesis; classification; deficiency; diagnostic use; drug effects; economics; genetics; history; immunology; isolation & purification; metabolism; pharmacokinetics; pharmacology; physiology; poisoning; radiation effects; secretion; standards; supply & distribution; therapeutic use; toxicity; ultrastructure; urine; chemistry; contraindications;

Tree Number: D08.811.277.656.300.760;

History Note: 2000(1988)