Serotonin - Physiology
Research News and Information

Saturday, November 21, 2009

Autocrine and paracrine roles for ATP and serotonin in mouse taste buds.

2 Nov 2009 Receptor (type II) taste bud cells secrete ATP during taste stimulation. In turn, ATP activates adjacent presynaptic (type III) cells to release serotonin (5-hydroxytryptamine, or 5-HT) and norepinephrine (NE). The roles of these neurotransmitters ... Read more...

Fast synaptic subcortical control of hippocampal circuits.

14 Oct 2009 Cortical information processing is under state-dependent control of subcortical neuromodulatory systems. Although this modulatory effect is thought to be mediated mainly by slow nonsynaptic metabotropic receptors, other mechanisms, such as direct ... Read more...

[Pharmacological studies on responsiveness of 5-hydroxytryptamine in overcoming perioperative spasm of coronary artery bypass graft]

30 Aug 2009 In ischemic heart diseases, the use of the internal thoracic artery (ITA) as an arterial graft has been associated with longer survival and better quality of life. However, it has been reported that vasospasm of the ITA graft frequently occurs and ... Read more...

Latest indexed articles for 'Serotonin - Physiology'

These are the very latest articles for this heading:

• Autocrine and paracrine roles for ATP and serotonin in mouse taste buds. 2 Nov 2009
• Deciphering the interaction of the corticotropin-releasing factor and serotonin brain systems in anxiety-related disorders. 2 Nov 2009
• Fast synaptic subcortical control of hippocampal circuits. 14 Oct 2009
• [Pharmacological studies on responsiveness of 5-hydroxytryptamine in overcoming perioperative spasm of coronary artery bypass graft] 30 Aug 2009
• Descending serotonergic facilitation and the antinociceptive effects of pregabalin in a rat model of osteoarthritic pain. 5 Aug 2009
• Increased frequency of prediabetes in patients with irritable bowel syndrome. 30 Jul 2009
• Corticotropin-releasing factor, serotonin, and sex: keys to the castle of depressive illness. 30 Jul 2009
• 5-hydroxytryptamine modulates migration, cytokine and chemokine release and T-cell priming capacity of dendritic cells in vitro and in vivo. 29 Jul 2009
• Endocannabinoids suppress excitatory synaptic transmission to dorsal raphe serotonin neurons through the activation of presynaptic CB1 receptors. 8 Jul 2009
• Neural reconnection in the transected spinal cord of the freshwater turtle Trachemys dorbignyi. 8 Jul 2009
• [Local GABA-ergic modulation of serotonergic neuron activity in the nucleus raphe magnus] 29 Jun 2009
• [Hormones and osteoporosis update. Regulation of bone remodeling by neuropeptides and neurotransmitters] 29 Jun 2009
• Evaluating the role of serotonin in hot flashes after breast cancer using acute tryptophan depletion. 29 Jun 2009
• The bright side of being blue: depression as an adaptation for analyzing complex problems. 29 Jun 2009
• Enhancement of the function of rat serotonin and norepinephrine neurons by sustained vagus nerve stimulation. 29 Jun 2009
• The effects of tryptophan depletion on neural responses to emotional words in remitted depression. 15 Jun 2009
• The role of serotonin in the pathophysiology of depression: as important as ever. 2 Jun 2009
• Investigation of 17 candidate genes for personality traits confirms effects of the HTR2A gene on novelty seeking. 30 May 2009
• The neurochemistry of fairness: clarifying the link between serotonin and prosocial behavior. 30 May 2009
• Synapse- and stimulus-specific local translation during long-term neuronal plasticity. 12 May 2009

See a longer list of these articles.

Technical information about 'Serotonin'

Definition: A biochemical messenger and regulator, synthesized from the essential amino acid L-TRYPTOPHAN. In humans it is found primarily in the central nervous system, gastrointestinal tract, and blood platelets. Serotonin mediates several important physiological functions including neurotransmission, gastrointestinal motility, hemostasis, and cardiovascular integrity. Multiple receptor families (RECEPTORS, SEROTONIN) explain the broad physiological actions and distribution of this biochemical mediator.

Chemical name: 1H-Indol-5-ol, 3-(2-aminoethyl)-

Registry Number: 50-67-9

Descriptor UI: D012701

Alternative terms: Serotonin; 5-Hydroxytryptamine; 5 Hydroxytryptamine; 3-(2-Aminoethyl)-1H-indol-5-ol; 5-HT; Enteramine; Hippophaine; Hydroxytryptamine;

Related Mesh Headings: Receptors, Serotonin; Serotonin Agents; Serotonin Syndrome;

Allowable Qualifiers: administration & dosage; adverse effects; analogs & derivatives; analysis; biosynthesis; blood; cerebrospinal fluid; chemical synthesis; classification; deficiency; diagnostic use; economics; genetics; history; immunology; isolation & purification; metabolism; pharmacokinetics; pharmacology; physiology; poisoning; radiation effects; secretion; standards; supply & distribution; therapeutic use; toxicity; urine; chemistry; contraindications;

Pharmacological Action: Serotonin Agents;

Tree Number: D02.092.211.215.801.852; D03.438.473.914.814; D23.469.050.650;

Online Note: use SEROTONIN to search HYDROXYTRYPTAMINE 1975-92

History Note: HYDROXYTRYPTAMINE was see SEROTONIN 1975-92

Technical Notes: /antag = SEROTONIN ANTAGONISTS but consider also SEROTONIN UPTAKE INHIBITORS