Serotonin - Therapeutic use
Research News and Information

Sunday, November 22, 2009

[Research of interactions in the dopamine-serotonin-somatostatin system promises new outlook in fundamental and practical respects]

27 Feb 2009 Dopamine and serotonin are the two important key neurotransmitters, which participate in the formation and regulation of various physiological parameters in the normal and pathological states. It is very interesting and important in both fundamental ... Read more...

Calcitonin gene-related peptide receptor antagonism does not affect the severity of myocardial ischemia during atrial pacing in dogs with coronary artery stenosis.

5 Nov 2008 Calcitonin gene-related peptide (CGRP) is a sensory neuropeptide that also has potent vasodilator activity. There are conflicting preclinical reports regarding the effect of CGRP receptor antagonism in the setting of myocardial ischemia. The present ... Read more...

Increased oxidant activity mediates vascular dysfunction in vibration injury.

25 Oct 2008 Occupational exposure to hand-operated vibrating tools causes a spectrum of pathological changes in the vascular, neurological, and musculoskeletal systems described as the hand-arm vibration syndrome (HAVS). Experiments were performed to determine ... Read more...

Latest indexed articles for 'Serotonin - Therapeutic use'

These are the very latest articles for this heading:

• [Research of interactions in the dopamine-serotonin-somatostatin system promises new outlook in fundamental and practical respects] 27 Feb 2009
• Calcitonin gene-related peptide receptor antagonism does not affect the severity of myocardial ischemia during atrial pacing in dogs with coronary artery stenosis. 5 Nov 2008
• Increased oxidant activity mediates vascular dysfunction in vibration injury. 25 Oct 2008
• Understanding behavior: serotonin syndrome. 30 Aug 2008
• Anticonvulsant serotonergic and deep brain stimulation in anterior thalamus. 27 Jul 2008
• Antiplatelet drugs. 28 May 2008
• Indolealkylamines: biotransformations and potential drug-drug interactions. May 2008
• 5-Hydroxytryptamine lowers blood pressure in normotensive and hypertensive rats. 25 Feb 2008
• [The wound healing stimulation] 30 Dec 2007
• Budesonide/formoterol for maintenance and relief in uncontrolled asthma vs. high-dose salmeterol/fluticasone. 29 Sep 2007
• Serotonin neuron transplants exacerbate L-DOPA-induced dyskinesias in a rat model of Parkinson's disease. 23 Jul 2007
• Serotonin but not zonisamide inhibits theophylline-induced epileptiform activity in guinea pig hippocampal CA3 neurons. 10 Jul 2007
• Enhancement of docetaxel efficacy in head and neck cancer treatment by G0 cell stimulation. 21 May 2007
• [The role of the serotoninergic system in the pathogenesis of experimental ulcerous colitis] 30 Dec 2006
• Peripheral sympathetic component of the temporomandibular joint inflammatory pain in rats. 29 Nov 2006
• Pharmacotherapy of aphasia: myth or reality? 16 Sep 2006
• Serotonergic mechanisms in amyotrophic lateral sclerosis. 29 Jun 2006
• Blocking of striated muscle degeneration by serotonin in C. elegans. 20 Jun 2006
• The effect of serotonin and serotonin antagonists on bladder cancer cell proliferation. 27 Feb 2006
• Enteric nervous system. 27 Feb 2006

See a longer list of these articles.

Technical information about 'Serotonin'

Definition: A biochemical messenger and regulator, synthesized from the essential amino acid L-TRYPTOPHAN. In humans it is found primarily in the central nervous system, gastrointestinal tract, and blood platelets. Serotonin mediates several important physiological functions including neurotransmission, gastrointestinal motility, hemostasis, and cardiovascular integrity. Multiple receptor families (RECEPTORS, SEROTONIN) explain the broad physiological actions and distribution of this biochemical mediator.

Chemical name: 1H-Indol-5-ol, 3-(2-aminoethyl)-

Registry Number: 50-67-9

Descriptor UI: D012701

Alternative terms: Serotonin; 5-Hydroxytryptamine; 5 Hydroxytryptamine; 3-(2-Aminoethyl)-1H-indol-5-ol; 5-HT; Enteramine; Hippophaine; Hydroxytryptamine;

Related Mesh Headings: Receptors, Serotonin; Serotonin Agents; Serotonin Syndrome;

Allowable Qualifiers: administration & dosage; adverse effects; analogs & derivatives; analysis; biosynthesis; blood; cerebrospinal fluid; chemical synthesis; classification; deficiency; diagnostic use; economics; genetics; history; immunology; isolation & purification; metabolism; pharmacokinetics; pharmacology; physiology; poisoning; radiation effects; secretion; standards; supply & distribution; therapeutic use; toxicity; urine; chemistry; contraindications;

Pharmacological Action: Serotonin Agents;

Tree Number: D02.092.211.215.801.852; D03.438.473.914.814; D23.469.050.650;

Online Note: use SEROTONIN to search HYDROXYTRYPTAMINE 1975-92

History Note: HYDROXYTRYPTAMINE was see SEROTONIN 1975-92

Technical Notes: /antag = SEROTONIN ANTAGONISTS but consider also SEROTONIN UPTAKE INHIBITORS