Serotonin Antagonists - Pharmacology
Research News and Information

Monday, November 23, 2009

Selective serotonin receptor stimulation of the medial nucleus accumbens causes differential effects on food intake and locomotion.

29 Sep 2009 Substantial evidence suggests that pharmacological manipulations of neural serotonin pathways influence ingestive behaviors. Despite the known role of the nucleus accumbens in directing appetitive and consummatory behavior, there has been little ... Read more...

Differential effects of topiramate on prefrontal glutamatergic transmission when combined with raclopride or clozapine.

29 Sep 2009 Treatment with topiramate may improve negative symptoms in schizophrenia when added to typical antipsychotic drugs (APDs) but not to clozapine. Both dopaminergic and glutamatergic transmissions in the medial prefrontal cortex (mPFC) are facilitated ... Read more...

Mechanisms by which the serotonergic system inhibits micturition in rats.

31 Aug 2009 AIMS: Serotonergic neurons and amino acid neurons are involved in the central nervous control of lower urinary tract function. We investigated the role of the serotonergic system in the central regulation of micturition, as well as the relationship ... Read more...

Latest indexed articles for 'Serotonin Antagonists - Pharmacology'

These are the very latest articles for this heading:

• Selective serotonin receptor stimulation of the medial nucleus accumbens causes differential effects on food intake and locomotion. 29 Sep 2009
• Differential effects of topiramate on prefrontal glutamatergic transmission when combined with raclopride or clozapine. 29 Sep 2009
• Mechanisms by which the serotonergic system inhibits micturition in rats. 31 Aug 2009
• Effect of yokukansan, a traditional Japanese medicine, on social and aggressive behaviour of para-chloroamphetamine-injected rats. 30 Aug 2009
• Inhibitory effect of serotonin antagonists on JC virus propagation in a carrier culture of human neuroblastoma cells. 30 Aug 2009
• Effects of chronic blockade of 5-HT(6) receptors on NMDA receptor subunits expression. 30 Aug 2009
• Serotonergic-postsynaptic receptors modulate gripping-induced immobility episodes in male taiep rats. 30 Aug 2009
• [Update: Current clinical developments in pulmonary hypertension] 26 Aug 2009
• In vivo evidence that constitutive activity of serotonin2C receptors in the medial prefrontal cortex participates in the control of dopamine release in the rat nucleus accumbens: differential effects of inverse agonist versus antagonist. 20 Aug 2009
• Synthesis, potency, and in vivo evaluation of 2-piperazin-1-ylquinoline analogues as dual serotonin reuptake inhibitors and serotonin 5-HT1A receptor antagonists. 11 Aug 2009
• Serotonergic modulation of crayfish hindgut. 30 Jul 2009
• Activity of the 5-HT1A receptor is involved in the alteration of glucocorticoid receptor in hippocampus and corticotropin-releasing factor in hypothalamus in SPS rats. 30 Jul 2009
• Interactions of serotonin (5-HT)2 receptor-targeting ligands and nicotine: locomotor activity studies in rats. 30 Jul 2009
• Activation of human enteric neurons by supernatants of colonic biopsy specimens from patients with irritable bowel syndrome. 26 Jul 2009
• APD791, 3-methoxy-n-(3-(1-methyl-1h-pyrazol-5-yl)-4-(2-morpholinoethoxy)phenyl)benzamide, a novel 5-hydroxytryptamine 2A receptor antagonist: pharmacological profile, pharmacokinetics, platelet activity and vascular biology. 21 Jul 2009
• Neurochemical mechanisms of consolidation of associative aversive learning to food in the common snail. 20 Jul 2009
• Ondansetron and fluoxetine reduce sleep apnea in mice lacking monoamine oxidase A. 13 Jul 2009
• [Comparison of the effects of selank and tuftsin on the metabolism of serotonin in the brain of rats pretreated with PCPA] 29 Jun 2009
• A high-throughput screen for chemicals that increase the lifespan of Caenorhabditis elegans. 29 Jun 2009
• Enhancement of the function of rat serotonin and norepinephrine neurons by sustained vagus nerve stimulation. 29 Jun 2009

See a longer list of these articles.

Technical information about 'Serotonin Antagonists'

Definition: Drugs that bind to but do not activate serotonin receptors, thereby blocking the actions of serotonin or serotonin agonists.

Registry Number: 0

Descriptor UI: D012702

Alternative terms: Serotonin Antagonists; Antagonists, Serotonin; 5-Hydroxytryptamine Antagonists; 5 Hydroxytryptamine Antagonists; Antagonists, 5-HT; Antagonists, 5 HT; 5-HT Antagonists; 5 HT Antagonists; Antagonists, 5-Hydroxytryptamine; Antagonists, 5 Hydroxytryptamine; Antiserotonergic Agents; Agents, Antiserotonergic; Serotonin Blockaders; Blockaders, Serotonin;

Related Mesh Headings: Serotonin Uptake Inhibitors;

Allowable Qualifiers: administration & dosage; adverse effects; analysis; blood; cerebrospinal fluid; chemical synthesis; classification; diagnostic use; economics; history; immunology; isolation & purification; metabolism; pharmacokinetics; pharmacology; poisoning; radiation effects; standards; supply & distribution; therapeutic use; toxicity; urine; chemistry; contraindications;

Tree Number: D27.505.519.625.850.850; D27.505.696.577.850.850;

Online Note: search SEROTONIN /antagonists & inhibitors 1968-77 & SEROTONIN 1966-67

History Note: 78,64-67

Technical Notes: GEN or unspecified; prefer specifics; differentiate from SEROTONIN UPTAKE INHIBITORS: read MeSH definition; do not confuse with SEROTONIN AGONISTS; DF: SEROTONIN ANTAG