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Serotonin Uptake Inhibitors - Therapeutic use
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Definition of 'Serotonin Uptake Inhibitors'

Compounds that specifically inhibit the reuptake of serotonin in the brain. This increases the serotonin concentration in the synaptic cleft which then activates serotonin receptors to a greater extent. These agents have been used in treatment of depression, panic disorder, obsessive-compulsive behavior, and alcoholism, as analgesics, and to treat obesity and bulimia. Many of the ADRENERGIC UPTAKE INHIBITORS also inhibit serotonin uptake; they are not included here.

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Thursday, March 18, 2010

[Narcolepsy and other hypersomnias]

6 Oct 2009 BACKGROUND: Narcolepsy is currently categorized into three groups; narcolepsy with and without emotionally triggered loss of muscle tone (cataplexy), and narcolepsy secondary to other medical conditions. Many patients with hypersomnia are diagnosed ... Read more...


Treatment of neuropathic pain: an overview of recent guidelines.

29 Sep 2009 A number of different treatments for neuropathic pain have been studied, but the literature is sizable, rapidly evolving, and lacks important information about practical aspects of patient management. Under the auspices of the International ... Read more...


Pharmacotherapy for depressed pregnant women: overcoming obstacles to gathering essential data.

29 Sep 2009 Approximately 3% of pregnant women take antidepressant medications. Information on the impact of antidepressants on short- and long-term maternal and offspring outcomes is highly desirable but neglected. The position that the dearth of treatment ... Read more...

 

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Technical information about 'Serotonin Uptake Inhibitors'

Definition: Compounds that specifically inhibit the reuptake of serotonin in the brain. This increases the serotonin concentration in the synaptic cleft which then activates serotonin receptors to a greater extent. These agents have been used in treatment of depression, panic disorder, obsessive-compulsive behavior, and alcoholism, as analgesics, and to treat obesity and bulimia. Many of the ADRENERGIC UPTAKE INHIBITORS also inhibit serotonin uptake; they are not included here.

Registry Number: 0

Descriptor UI: D017367

Alternative terms: Serotonin Uptake Inhibitors; Uptake Inhibitors, 5-HT; Uptake Inhibitors, 5 HT; 5-HT Uptake Inhibitors; 5 HT Uptake Inhibitors; Inhibitors, 5-Hydroxytryptamine Uptake; Inhibitors, 5 Hydroxytryptamine Uptake; Uptake Inhibitors, 5-Hydroxytryptamine; Uptake Inhibitors, 5 Hydroxytryptamine; Inhibitors, Serotonin Reuptake; Reuptake Inhibitors, Serotonin; Serotonin Reuptake Inhibitors; Inhibitors, Serotonin Uptake; Uptake Inhibitors, Serotonin; Inhibitors, 5-HT Uptake; Inhibitors, 5 HT Uptake; 5-Hydroxytryptamine Uptake Inhibitors; 5 Hydroxytryptamine Uptake Inhibitors;

Related Mesh Headings: Antidepressive Agents, Second-Generation; Adrenergic Uptake Inhibitors;

Allowable Qualifiers: administration & dosage; adverse effects; analysis; antagonists & inhibitors; blood; cerebrospinal fluid; chemical synthesis; classification; diagnostic use; economics; history; immunology; isolation & purification; metabolism; pharmacokinetics; pharmacology; poisoning; radiation effects; standards; supply & distribution; therapeutic use; toxicity; urine; chemistry; contraindications; agonists;

Tree Number: D27.505.519.625.600.850; D27.505.519.625.850.900; D27.505.696.577.600.850; D27.505.696.577.850.900;

History Note: 93

Technical Notes: GEN or unspecified; prefer specifics; do not confuse with SEROTONIN ANTAGONISTS; DF: SEROTONIN UPTAKE INHIB

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